Search Results - "Oliveira, José Miguel"
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Sustainable Valorization of Tomato By-Products to Obtain Bioactive Compounds: Their Potential in Inflammation and Cancer Management
Published in Molecules (Basel, Switzerland) (04-03-2022)“…Tomato producing and processing industries present undoubted potential for industrial discarded products valorization whether due to the overproduction of…”
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Therapeutic potential of hesperidin and its aglycone hesperetin: Cell cycle regulation and apoptosis induction in cancer models
Published in Phytomedicine (Stuttgart) (15-07-2020)“…The ability of cancer cells to divide without restriction and to escape programmed cell death is a feature of the proliferative state. Citrus flavanones are…”
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Antioxidant mechanisms to counteract TiO2-nanoparticles toxicity in wheat leaves and roots are organ dependent
Published in Journal of hazardous materials (15-12-2019)“…[Display omitted] •TiO2-NP is toxic above 5 mg L−1, being wheat shoots more sensitive than roots.•Leaves triggered thiol and AsA metabolism to counteract…”
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Responses of olive plants exposed to different irrigation treatments in combination with heat shock: physiological and molecular mechanisms during exposure and recovery
Published in Planta (01-05-2019)“…Olive is traditionally cultivated in dry farming or in high water demanding irrigated orchards. The impact of climate change on these orchards remains to…”
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β-Carotene and its physiological metabolites: Effects on oxidative status regulation and genotoxicity in in vitro models
Published in Food and chemical toxicology (01-07-2020)“…Carotenoids are ubiquitously distributed in nature, β-carotene being the most frequently found carotenoid in the human diet. In the human body, β-carotene is…”
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The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes
Published in Oxidative medicine and cellular longevity (01-01-2016)“…Lycopene has been reported as the antioxidant most quickly depleted in skin upon UV irradiation, and thus it might play a protective role. Our goal was to…”
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Proteomics of industrial fungi: trends and insights for biotechnology
Published in Applied microbiology and biotechnology (01-01-2011)“…Filamentous fungi are widely known for their industrial applications, namely, the production of food-processing enzymes and metabolites such as antibiotics and…”
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Sulforaphane Induces DNA Damage and Mitotic Abnormalities in Human Osteosarcoma MG-63 Cells: Correlation with Cell Cycle Arrest and Apoptosis
Published in Nutrition and cancer (01-02-2014)“…Osteosarcoma is a recalcitrant bone malignancy with poor responsiveness to treatments; therefore, new chemotherapeutic compounds are needed. Sulforaphane (SFN)…”
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Photosynthesis light-independent reactions are sensitive biomarkers to monitor lead phytotoxicity in a Pb-tolerant Pisum sativum cultivar
Published in Environmental science and pollution research international (01-01-2015)“…Lead (Pb) environmental contamination remains prevalent. Pisum sativum L. plants have been used in ecotoxicological studies, but some cultivars showed to…”
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Cadmium-induced genotoxicity in human osteoblast-like cells
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-12-2014)“…•Cd induced a dose dependent decrease in viability of osteoblast-like-cells MG-63.•Cd decreased the number of cells at G0/G1 and induced cell cycle delay at…”
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High-salinity activates photoprotective mechanisms in Quercus suber via accumulation of carbohydrates and involvement of non-enzymatic and enzymatic antioxidant pathways
Published in New forests (01-03-2022)“…Cork oak ( Quercus suber ), native to Mediterranean areas, is a plant of ecological and economical relevance, nevertheless, the effects of soil salinization on…”
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Insights into the impact of silver nanoparticles on human keratinocytes metabolism through NMR metabolomics
Published in Archives of biochemistry and biophysics (01-01-2016)“…Due to their antimicrobial properties, silver nanoparticles (AgNPs) are increasingly incorporated into consumer goods and medical products. Their potential…”
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Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models
Published in Archives of toxicology (01-03-2018)“…Osteosarcoma chemotherapy is often limited by chemoresistance, resulting in poor prognosis. Combined chemotherapy could, therefore, be used to prevent…”
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Cytotoxic effect of the serotonergic drug 1-(1-Naphthyl)piperazine against melanoma cells
Published in Toxicology in vitro (01-03-2018)“…1-(1-Naphthyl)piperazine (1-NPZ) is a serotonergic derivative of quipazine acting both as antagonist and agonist of different serotonin receptors, with…”
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Sulforaphane induces oxidative stress and death by p53-independent mechanism: implication of impaired glutathione recycling
Published in PloS one (25-03-2014)“…Sulforaphane (SFN) is a naturally-occurring isothiocyanate best known for its role as an indirect antioxidant. Notwithstanding, in different cancer cell lines,…”
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Biochemical and transcriptional analyses of cadmium-induced mitochondrial dysfunction and oxidative stress in human osteoblasts
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2018)“…Cadmium (Cd) accumulation is known to occur predominantly in kidney and liver; however, low-level long-term exposure to Cd may also result in bone damage. Few…”
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Dataset of chicken-embryo blood cells exposed to quercetin, methyl methanesulfonate, or cadmium chloride
Published in Data in brief (01-12-2023)“…Toxicological analysis of the effects of natural compounds is frequently mandated to assess their safety. In addition to more simple in vitro cellular systems,…”
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Inorganic Hg toxicity in plants: A comparison of different genotoxic parameters
Published in Plant physiology and biochemistry (01-04-2018)“…Inorganic Mercury (Hg) contamination persists an environmental problem, but its cyto- and genotoxicity in plants remains yet unquantified. To determine the…”
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Quercus suber Roots Activate Antioxidant and Membrane Protective Processes in Response to High Salinity
Published in Plants (Basel) (19-02-2022)“…Cork oak ( ) is a species native to Mediterranean areas and its adaptation to the increasingly prevalent abiotic stresses, such as soil salinization, remain…”
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Hesperetin-etoposide combinations induce cytotoxicity in U2OS cells: Implications on therapeutic developments for osteosarcoma
Published in DNA repair (01-02-2017)“…[Display omitted] •Hesperetin is cytotoxic to osteosarcoma U2OS cells and promotes cytostasis.•Hesperetin can show additive effects with etoposide to decrease…”
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