Search Results - "Oliveira, João E."
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Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice
Published in Endocrinology (Philadelphia) (01-01-2019)“…Previous studies have shown that bromocriptine mesylate (Bromo) lowers blood glucose levels in adults with type 2 diabetes mellitus; however, the mechanism of…”
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N-Glycoprofiling Analysis for Carbohydrate Composition and Site-Occupancy Determination in a Poly-Glycosylated Protein: Human Thyrotropin of Different Origins
Published in International journal of molecular sciences (03-02-2017)“…Human thyrotropin (hTSH) is a glycoprotein with three potential glycosylation sites: two in the α-subunit and one in the β-subunit. These sites are not always…”
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Periplasmic synthesis and purification of the human prolactin antagonist Δ1-11-G129R-hPRL
Published in AMB Express (27-04-2021)“…The human prolactin antagonist Δ 1-11 -G129R-hPRL is a 21.9 kDa recombinant protein with 188 amino acids that downregulates the proliferation of a variety of…”
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Synthesis of Human Bone Morphogenetic Protein-2 (hBMP-2) in E. coli Periplasmic Space: Its Characterization and Preclinical Testing
Published in Cells (Basel, Switzerland) (14-12-2021)“…Human BMP-2, a homodimeric protein that belongs to the TGF- β family, is a recognized osteoinductor due to its capacity of inducing bone regeneration and…”
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Expression, purification, and characterization of authentic mouse prolactin obtained in Escherichia coli periplasmic space
Published in Biotechnology and applied biochemistry (01-05-2012)“…Prolactin (PRL) is a pleiotropic hormone produced by lactotroph cells of the anterior pituitary gland and is mainly related to lactation control and…”
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Screening for active pulmonary tuberculosis: Development and applicability of artificial neural network models
Published in Tuberculosis (Edinburgh, Scotland) (01-07-2018)“…Tuberculosis (TB) remains a significant public health challenge, motivated by the diversity of healthcare epidemiological settings, as other factors…”
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The Pattern of GH Action in the Mouse Brain
Published in Endocrinology (Philadelphia) (27-05-2024)“…Abstract GH acts in numerous organs expressing the GH receptor (GHR), including the brain. However, the mechanisms behind the brain's permeability to GH and…”
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Delayed culture conversion due to cigarette smoking in active pulmonary tuberculosis patients
Published in Tuberculosis (Edinburgh, Scotland) (01-01-2014)“…Summary Although many studies have assessed factors affecting culture conversion during tuberculosis treatment, few have looked into the effect of tobacco…”
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Improved Bioprocess with CHO-hTSH Cells on Higher Microcarrier Concentration Provides Higher Overall Biomass and Productivity for rhTSH
Published in Applied biochemistry and biotechnology (01-06-2011)“…Since the recombinant thyroid-stimulating hormone (rhTSH) is secreted by stably transfected Chinese hamster ovary (CHO-hTSH) cells, a bioprocess consisting of…”
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A universalização da pré-escola no Brasil: uma análise de determinantes históricos
Published in Brazilian Journal of Political Economy (01-06-2024)“…RESUMO A taxa líquida de matrícula na pré-escola aumentou de 3,7% para 78,9% entre 1970 e 2018. Este artigo analisa o processo de universalização da pré-escola…”
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Instrumented Office Chair With Low-Cost Plastic Optical Fiber Sensors for Posture Control and Work Conditions Optimization
Published in IEEE access (2022)“…People spend more and more time sitting and this habit has been shown to cause spine pathologies. Thus, the scientific community and the industry have become…”
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Determination of recombinant Interferon-α2 in E. coli periplasmic extracts by reversed-phase high-performance liquid chromatography
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-01-2018)“…•A HPLC method for direct analysis of IFN-α2 in periplasmic extracts.•A HPLC method for an accurate quali- and quantitative analysis of IFN-α2.•A fast method…”
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Smart Office Chair for Working Conditions Optimization
Published in IEEE access (01-01-2023)“…There is a growing tendency for people to spend more and more hours of their day sitting. This position leads to an increase in the postural problems in the…”
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Interview: Rising from the ashes
Published in Anthropology today (01-02-2019)Get full text
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Milonine attenuates the lipopolysaccharide-induced acute lung injury in mice by modulating the Akt/NF-κB signaling pathways
Published in Anais da Academia Brasileira de Ciências (01-01-2022)“…Abstract Acute lung injury is an inflammation that triggers acute respiratory distress syndrome with perialveolar neutrophil infiltration, alveolar-capillary…”
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N-glycoprofiling analysis in a simple glycoprotein model: A comparison between recombinant and pituitary glycosylated human prolactin
Published in Journal of biotechnology (20-05-2015)“…•Cyclohexemide greatly increased glycosylation site occupancy in CHO-derived G-hPRL.•N-glycan structures were determined in native and CHO-derived G-hPRL and…”
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Expression of glycosylated human prolactin in HEK293 cells and related N-glycan composition analysis
Published in AMB Express (29-08-2019)“…Prolactin (PRL) is a hormone produced by the pituitary gland with innumerable functions, such as lactation, reproduction, osmotic and immune regulation. The…”
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Enhancement of Human Thyrotropin Synthesis by Sodium Butyrate Addition to Serum-Free CHO Cell Culture
Published in Applied biochemistry and biotechnology (01-12-2013)“…The influence of sodium butyrate (NaBu) on the synthesis of recombinant human thyrotropin (r-hTSH) by CHO cells was investigated for the first time. A…”
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A Covid-19 e a volta às aulas: ouvindo as evidências
Published in Ensaio (Rio de Janeiro, Brazil) (01-09-2020)“…Resumo Paralisadas pelo pânico decorrente da pandemia provocada pela Covid-19, o fechamento das escolas trará consequências para a aprendizagem dos alunos…”
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