Is dental caries experience increased in HIV-infected children and adolescents? A meta-analysis

To undertake a systematic review to assess if HIV-infected children and adolescents have an increased dental caries experience. A search of MEDLINE, BIREME, EMBASE, GOOGLE SCHOLAR, SIGLE (Grey Literature) and reference lists of included studies was carried out. To be eligible the studies had to pres...

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Bibliographic Details
Published in:	Acta odontologica Scandinavica Vol. 73; no. 7; p. 481
Main Authors:	Oliveira, Cristiana Aroeira Guimarães Rosa, Tannure, Patricia Nivoloni, de Souza, Ivete Pomarico Ribeiro, Maia, Lucianne Cople, Portela, Maristela Barbosa, Castro, Gloria Fernanda B de A
Format:	Journal Article
Language:	English
Published:	England 01-01-2015
Subjects:	Adolescent Child Child, Preschool Dental Caries - epidemiology Disease Progression DMF Index HIV Infections - epidemiology Humans Infant Infant, Newborn Tooth, Deciduous - pathology dental caries HIV infections child
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Summary:	To undertake a systematic review to assess if HIV-infected children and adolescents have an increased dental caries experience. A search of MEDLINE, BIREME, EMBASE, GOOGLE SCHOLAR, SIGLE (Grey Literature) and reference lists of included studies was carried out. To be eligible the studies had to present HIV-infected and non-infected children/adolescents between 0-18 years old. To assess the methodological quality, the studies were categorized in scores from 'A' to 'C'. To perform a meta-analysis a random effect model was used with 95% confidence intervals and two distinct sub-group analyses were carried out in terms of caries progression: data for cavitated and non-cavitated lesions (sub-group 1) and data only for cavitated lesions (sub-group 2). Five studies fulfilled the selection criteria. Four studies (two ranked A and two B in the quality assessment) revealed higher caries scores in primary teeth in the HIV-infected patients with mean dmft/dmfs scores of 3.8-4.1/7.8-11.0 compared to the control group 1.5-2.4/3.4-5.1. No differences in caries index were found for permanent dentition. The meta-analysis excluded caries data of permanent teeth and showed a significant association between caries experience in primary dentition and HIV infection considering cavitated and non-cavitated lesions (OR = 2.33, 95% CI = 1.48-3.68) or only cavitated lesions (OR = 2.98, 95% CI = 1.59-5.59). Evidence exists that suggests HIV-infected children/adolescents have an increased caries experience in primary dentition.
ISSN:	1502-3850
DOI:	10.3109/00016357.2014.958874