Search Results - "Oliveira, Carla R.P."
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Circulating microRNA profile in humans and mice with congenital GH deficiency
Published in Aging cell (01-07-2021)“…Reduced inflammation, increased insulin sensitivity, and protection against cancer are shared between humans and mice with GH/IGF1 deficiency. Beyond hormone…”
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2
Enteroendocrine Connections in Congenital Isolated GH Deficiency Due to a GHRH Receptor Gene Mutation
Published in The journal of clinical endocrinology and metabolism (01-07-2019)“…Abstract Context GH and IGF-1 are crucial for attainment of normal body size and regulation of food intake, nutrient storage, and insulin sensitivity…”
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3
Abnormal vascular and neural retinal morphology in congenital lifetime isolated growth hormone deficiency
Published in Growth hormone & IGF research (01-10-2016)“…Abstract Objective Experimental models demonstrate an important role of GH in retinal development. However, the interactions between GH and the…”
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4
Ocular findings in adult subjects with an inactivating mutation in GH releasing hormone receptor gene
Published in Growth hormone & IGF research (01-06-2017)“…Abstract Objective Ocular function is fundamental for environmental adaptation and survival capacity. Growth factors are necessary for a mature eyeball, needed…”
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5
Voice Formants in Individuals With Congenital, Isolated, Lifetime Growth Hormone Deficiency
Published in Journal of voice (01-05-2016)“…Summary Objective To analyze the voice formants (F1, F2, F3, and F4 in Hz) of seven oral vowels, in Brazilian Portuguese, [a, ε, e, i, ɔ, o, and u] in adult…”
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6
Adipokine Profile and Urinary Albumin Excretion in Isolated Growth Hormone Deficiency
Published in The journal of clinical endocrinology and metabolism (01-02-2010)“…Background: GH deficiency (GHD) is often associated with cardiovascular risk factors, including abdominal fat accumulation, hypercholesterolemia, and increased…”
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7
Voice Quality in Short Stature With and Without GH Deficiency
Published in Journal of voice (01-09-2012)“…Summary Objective The aim of this study was to analyze the individual impact of short stature (SS) or untreated isolated growth hormone deficiency (IGHD) on…”
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8
Quality of life in congenital, untreated, lifetime isolated growth hormone deficiency
Published in Psychoneuroendocrinology (01-07-2009)“…Summary Impaired quality of life (QoL) is commonly described as being associated with growth hormone (GH) deficiency (GHD), and beneficial effects of GH…”
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9
Phenotypic variation among four family members with congenital hypothyroidism caused by two distinct thyroglobulin gene mutations
Published in Thyroid (New York, N.Y.) (01-07-2008)“…Thyroglobulin (Tg) is a large glycoprotein that is intimately involved in the biosynthesis of thyroxine and triiodothyronine. At least 38 mutations have been…”
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10
Older individuals heterozygous for a growth hormone-releasing hormone receptor gene mutation are shorter than normal subjects
Published in Journal of human genetics (01-06-2015)“…Growth hormone (GH)-releasing hormone (GHRH) is the most important stimulus for GH secretion by the pituitary gland. Subjects homozygous for GHRH receptor…”
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Papel emergente do eixo GH/IGF-I no controle cardiometabólico
Published in Arquivos brasileiros de cardiologia (01-11-2011)“…O hormônio de crescimento (GH), principal regulador do crescimento pós-natal, tem importantes ações metabólicas em diferentes tecidos, sinérgicas ou até…”
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12
Brain morphometry and estimation of aging brain in subjects with congenital untreated isolated GH deficiency
Published in Journal of endocrinological investigation (01-11-2024)“…Purpose Individuals with isolated GH deficiency (IGHD) due to a mutation in the GHRH receptor gene have a normal life expectancy and above 50 years of age,…”
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13
Skin assessment in congenital untreated isolated GH deficiency
Published in Endocrine (01-06-2024)“…Purpose The separation between the inside and outside through the skin was fundamental for the evolution of prevertebrates, which grow through extrapituitary…”
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Function and form of the shoulder in congenital and untreated growth hormone deficiency
Published in Endocrine (01-09-2023)“…Objectives The shoulder is the most mobile joint in the entire human body. During arm elevation, it requires the integrity of a set of muscles, bones, and…”
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15
Adult individuals with congenital, untreated, severe isolated growth hormone deficiency have satisfactory muscular function
Published in Endocrine (01-01-2019)“…Purpose While growth hormone (GH) and the insulin-like growth factor type I (IGF-I) are known to exert synergistic actions on muscle anabolism, the…”
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Reduced fibroblast growth factor 21 and β-Klotho secretion in untreated congenital isolated GH deficiency
Published in Endocrine (01-07-2021)“…Purposes Increasing evidence suggests that the FGF-Klotho endocrine system and the somatotropic system (pituitary and extra-pituitary GH) may have important…”
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Altered sleep patterns in patients with non-functional GHRH receptor
Published in European journal of endocrinology (01-07-2017)“…Objectives GH-releasing hormone (GHRH) exerts hypnotic actions increasing the non-rapid eye movement (NREM) sleep. Conversely, GH stimulates the REM sleep. GH…”
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Individuals with isolated congenital GH deficiency due to a GHRH receptor gene mutation appear to cope better with SARS-CoV-2 infection than controls
Published in Endocrine (01-05-2021)“…Purpose Several interactions exist between the GH/IGF axis and the immune system, including effects on innate immunity and humoral and cellular response…”
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Cerebral vasoreactivity, a surrogate marker of cerebrovascular disease, is not impaired in subjects with lifetime, untreated, congenital isolated GH deficiency
Published in Endocrine (01-11-2020)“…Objectives Cerebrovascular disease (CeVD) is a major cause of death and disability. The role of the GH/IGF-I axis on CeVD risk is controversial. Patients with…”
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Predictive factors for the diagnosis of permanent congenital hypothyroidism and its temporal changes in Sergipe, Brazil - A real-life retrospective study
Published in Archives of Endocrinology and Metabolism (2023)“…Congenital hypothyroidism (CH) can be permanent (PCH) or transient (TCH). While the importance of thyroxine in myelination of the brain is undisputed, the…”
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