Search Results - "Oliveira, Brás H."
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Preparation of betulinic acid derivatives by chemical and biotransformation methods and determination of cytotoxicity against selected cancer cell lines
Published in European journal of medicinal chemistry (01-10-2013)“…Several novel 2,4-dinitrophenylhydrazone betulinic acid derivatives have been prepared by chemical and biotransformation methods using fungi and carrot cells…”
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2
Biotransformation of betulinic and betulonic acids by fungi
Published in Phytochemistry (Oxford) (01-03-2007)“…The biotransformation of betulinic (R = OH) and betulonic acid (R = O) by Arthrobotrys sp., Colletotrichum sp., Chaetophoma sp. and Dematium sp. oxidized the…”
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3
HPLC/DAD determination of rosmarinic acid in Salvia officinalis: sample preparation optimization by factorial design
Published in Journal of the Brazilian Chemical Society (01-01-2013)“…Sage (Salvia officinalis) contains high amounts of the biologically active rosmarinic acid (RA) and other polyphenolic compounds. RA is easily oxidized, and…”
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4
Enzymatic modification of stevioside by cell-free extract of Gibberella fujikuroi
Published in Journal of biotechnology (01-08-2007)“…Stevioside is a natural sweetener obtained from the leaves of Stevia rebaudiana. It is a glycoside of steviol and other glycosides of the same aglycone are…”
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5
rac-2-[(2-Chloro-phen-yl)(4-chloro-phen-yl)meth-yl]-1,3-dioxolane
Published in Acta crystallographica. Section E, Structure reports online (01-07-2012)“…The title compound, C(16)H(14)Cl(2)O(2), is a chiral mitotane derivative that contains a dioxolane ring and crystallizes from methanol as a racemic mixture. It…”
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6
Eupafolin: Effect on mitochondrial energetic metabolism
Published in Bioorganic & medicinal chemistry (15-01-2008)“…In this study the effects of eupafolin (6-methoxy 5,7,3′,4′-tetrahydroxyflavone), a flavone extracted from dry leaves of Eupatorium litoralle, on mitochondrial…”
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7
Gibberellic acid production by solid-state fermentation in coffee husk
Published in Applied biochemistry and biotechnology (01-07-2002)“…Five strains of Gibberella fujikuroi and one of Fusarium moniliforme were screened for the production of gibberellic acid (GA3) in coffee husk, and based on…”
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8
Determination of the triterpenoid, betulinic acid, in Doliocarpus schottianus by HPLC
Published in Phytochemical analysis (01-03-2002)“…The isolation, detection and quantification of betulinic acid in Doliocarpus schottianus are described. The isolation from the plant extract was made by column…”
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9
Activity of isosteviol lactone on mitochondrial metabolism
Published in Toxicology letters (05-06-2003)“…Isosteviol lactone (LAC), a lactone derivative of the diterpenic acid isosteviol (ISO) was evaluated for its effect on the oxidative metabolism of mitochondria…”
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10
Amino acid and monoamine alterations in the cerebral cortex and hippocampus of mice submitted to ricinine-induced seizures
Published in Pharmacology, biochemistry and behavior (01-07-2002)“…The alkaloid ricinine isolated from the plant Ricinus communis, when administered to mice at high doses, induces clonic seizures accompanied by…”
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11
Therapy of adrenocortical cancer: present and future
Published in American journal of cancer research (01-01-2011)“…Adrenocortical carcinoma is a rare endocrine malignancy with an estimated worldwide incidence of 0.5 - 2 per million/year. This neoplasm is characterized by a…”
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12
HPLC analysis of flavonoids in Eupatorium littorale
Published in Journal of the Brazilian Chemical Society (01-01-2001)“…The isolation and identification of eupafolin and hispidulin in the dried leaves of Eupatorium littorale (Asteraceae) are described. A method for the detection…”
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13
Mitotane associated with cisplatin, etoposide, and doxorubicin in advanced childhood adrenocortical carcinoma: mitotane monitoring and tumor regression
Published in Journal of pediatric hematology/oncology (01-08-2006)“…To define a mitotane dose for pediatric patients with adrenocortical cancer (ACC) that maintains therapeutic plasma levels (TL) between 14 and 20 microg/mL and…”
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Biotransformation of the diperpenoid, isosteviol, by Aspergillus niger, Penicillium chrysogenum and Rhizopus arrhizus
Published in Phytochemistry (Oxford) (01-07-1999)“…The biotransformation of isosteviol ( ent-16-ketobeyeran-19-oic acid) by three fungi is described. Aspergillus niger produced the 7β-OH derivative,…”
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Preparation of Derivatives of Betulinic Acid, Steviol and Isosteviol and Evaluation of Antitrypanosomal and Antimalarial Activities
Published in Journal of the Brazilian Chemical Society (01-06-2016)“…Derivatives of steviol, isosteviol and betulinic acid were prepared and tested in vitro against Plasmodium falciparum W2 (chloroquine-resistant) and…”
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16
Biotransformation of steviol derivatives by Aspergillus niger and Fusarium moniliforme
Published in Journal of the Brazilian Chemical Society (01-04-2005)Get full text
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Determination of the diterpenoid, kaurenoic acid, in Annona glabra by HPLC
Published in Phytochemical analysis (01-11-2002)“…The isolation of ent‐kaur‐16‐en‐19‐oic acid (1) from the leaves and bark of Annona glabra and its determination by reversed‐phase HPLC with a photodiode array…”
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18
Influence of rosmarinic acid and Salvia officinalis extracts on melanogenesis of B16F10 cells
Published in Revista brasileira de farmacognosia (01-03-2013)“…Melanin is a photoprotective skin pigment, and pathologies characterized by hypo or hyperpigmentation are common. New compounds that regulate melanogenesis…”
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Pharmacological Evaluation of Ricinine, a Central Nervous System Stimulant Isolated from Ricinus communis
Published in Pharmacology, biochemistry and behavior (01-07-1999)“…The extract of the pericarp of castor bean ( Ricinus communis) showed some typical central nervous system stimulant effects when administered to mice. The…”
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20
Effects of natural flavones on membrane properties and citotoxicity of HeLa cells
Published in Revista brasileira de farmacognosia (01-07-2010)“…The aim of this study was to determine whether eupafolin and hispidulin, flavones extracted from Eupatorium littorale Cabrera, Asteraceae, have the ability to…”
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