Search Results - "Oliveira, Anderson R. M. de"

Challenges of probe cocktail approach for human drug-drug interaction assays by Carrão, Daniel B, de Oliveira, Anderson RM, Magalhães, Igor RS

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ASYMMETRIC SULFOXIDATION OF ALBENDAZOLE TO RICOBENDAZOLE BY FUNGI: EFFECT OF pH by Barth, Thiago, Hilário, Viviane C., Rocha, Bruno A., Furtado, Niege A. J. C., Pupo, Mônica T., Oliveira, Anderson R. M. de

“…Albendazole (ABZ) is an anthelmintic drug used for the treatment of infectious diseases in veterinary and human medicine. This drug is a prochiral drug that…”
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Myclobutanil enantioselective risk assessment in humans through in vitro CYP450 reactions: Metabolism and inhibition studies by Fonseca, Franciele S., Carrão, Daniel B., de Albuquerque, Nayara C.P., Nardini, Viviani, Dias, Luís G., da Silva, Rodrigo M., Lopes, Norberto P., de Oliveira, Anderson R.M.

“…Myclobutanil is a chiral triazole fungicide that is employed worldwide. Although enantiomers have the same physical-chemical properties, they may differ in…”
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Interaction of a Triruthenium ortho-Metallated Phenazine with Cytochrome P450 Enzymes by do Nascimento, Luis Guilherme, Barbetta, Maike, Chaves, Otávio, de Oliveira, Anderson, Nikolaou, Sofia

“…The triruthenium ortho-metallated phenazine [Ru3O(CH3COO)5(py)2(dppzCl)]PF6 (1, py = pyridine; dppz-Cl = 7-chlorodipyrido[3,2-a:2’,3’-c]phenazine) is a…”
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Leishmanicidal Effects of Piperlongumine (Piplartine) and Its Putative Metabolites by Moreira, Fernanda de Lima, Riul, Thalita Bachelli, Moreira, Marcela de Lima, Pilon, Alan Cesar, Dias-Baruffi, Marcelo, Araújo, Márcio S S, Lopes, Norberto Peporine, de Oliveira, Anderson R M

“…Piperlongumine is an amide alkaloid found in Piperaceae species that shows a broad spectrum of biological properties, including antitumor and antiparasitic…”
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Metabolic profile and safety of piperlongumine by de Lima Moreira, Fernanda, Habenschus, Maísa D., Barth, Thiago, Marques, Lucas M. M., Pilon, Alan Cesar, da Silva Bolzani, Vanderlan, Vessecchi, Ricardo, Lopes, Norberto P., de Oliveira, Anderson R. M.

“…Piperlongumine (PPL), a natural plant product, has been extensively studied in cancer treatment going up on clinical trials. Since the first report related to…”
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In Vitro Inhibition of Human CYP450s 1A2, 2C9, 3A4/5, 2D6 and 2E1 by Grandisin by Habenschus, Maísa Daniela, Moreira, Fernanda de Lima, Lopes, Norberto Peporine, de Oliveira, Anderson R M

“…Grandisin, a lignan isolated from many species of plants, such as , is a potential drug candidate due to its biological properties, highlighted by its…”
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Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis by Muradás, Thaís C, Abbadi, Bruno L, Villela, Anne D, Macchi, Fernanda S, Bergo, Pedro F, de Freitas, Talita F, Sperotto, Nathalia D M, Timmers, Luis F S M, Norberto de Souza, Osmar, Picada, Jaqueline N, Fachini, Jean, da Silva, Juliana Bondan, de Albuquerque, Nayara C P, Habenschus, Maísa D, Carrão, Daniel B, Rocha, Bruno A, Barbosa Junior, Fernando, de Oliveira, Anderson R M, Mascarello, Alessandra, Neuenfeldf, Patrícia, Nunes, Ricardo J, Morbidoni, Héctor R, Campos, Maria M, Basso, Luiz A, Rodrigues-Junior, Valnês S

“…New effective compounds for tuberculosis treatment are needed. This study evaluated the effects of a series of quinoxaline-derived chalcones against…”
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Method validation and nanoparticle characterization assays for an innovative amphothericin B formulation to reach increased stability and safety in infectious diseases by Tadini, Maraine Catarina, de Freitas Pinheiro, Ana Maria, Carrão, Daniel Blascke, Aguillera Forte, Ana Luiza Scarano, Nikolaou, Sofia, de Oliveira, Anderson R.M., Berretta, Andresa Aparecida, Marquele-Oliveira, Franciane

“…[Display omitted] •NLC-AmB characterizations employing DLS, AFM, FT-IR and DSC/TGA demonstrated the nanosized scale of the DDS and evidenced the mechanical…”
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Pharmacokinetic properties, in vitro metabolism and plasma protein binding of govaniadine an alkaloid isolated from Corydalis govaniana Wall by Marques, Lucas M.M., Callejon, Daniel R., Pinto, Larissa G., de Campos, Michel L., de Oliveira, Anderson R.M., Vessecchi, Ricardo, Adhikari, Achyut, Shrestha, Ram L.S., Peccinini, Rosangela G., Lopes, Norberto P.

“…[Display omitted] •Govaniadine in vitro metabolism by liver microsomes investigated by the first time.•The in vitro metabolism yielded three…”
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In vitro metabolism studies of natural products are crucial in the early development of medicines by Moreira, Fernanda L., Marques, Lucas M. M., Lopes, Norberto P., de Oliveira, Anderson R. M.

“…Finding new drugs is imperative especially in the case of diseases such as serious infections and cancer, for which a gap in drug development exists…”
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In vitro metabolism of monensin A: microbial and human liver microsomes models by Rocha, Bruno A., Assis, Marilda D., Peti, Ana P. F., Moraes, Luiz A. B., Moreira, Fernanda L., Lopes, Norberto P., Pospíšil, Stanislav, Gates, Paul J., de Oliveira, Anderson R. M.

“…Abstract 1. Monensin A, an important antibiotic ionophore that is primarily employed to treat coccidiosis, selectively complexes and transports sodium cations…”
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Enantioselective fungal biotransformation of risperidone in liquid culture medium by capillary electrophoresis and hollow fiber liquid-phase microextraction by de Jesus, Liana I., Albuquerque, Nayara C. P., Borges, Keyller B., Simões, Rodrigo A., Calixto, Leandro A., Furtado, Niege A. J. C., de Gaitani, Cristiane M., Pupo, Mônica T., de Oliveira, Anderson R. M.

“…Knowing that microbial transformations of compounds play vital roles in the preparation of new derivatives with biological activities, risperidone and its…”
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Biomimetic oxidation studies of monensin A catalyzed by metalloporphyrins: Identification of hydroxyl derivative product by electrospray tandem mass spectrometry by Sousa-Junior, José N., Rocha, Bruno A., Assis, Marilda D., Peti, Ana P.F., Moraes, Luiz A.B., Iamamoto, Yassuko, Gates, Paul J., de Oliveira, Anderson R.M., Lopes, Norberto P.

“…Monensin A is an important commercially available natural product isolated from Streptomyces cinnamonensins that shows antibiotic and anti-parasitic…”
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Biomimetic Metabolism of Kaurenoic Acid Validated by Microsomal Reactions by Fernandes, Eduardo Felipe Alves, de Oliveira, Anderson R.M., Barros, Valeria Priscila, Guaratini, Thais, Lopes, Norberto Peporine

“…The cytochrome P450 is a remarkable family of enzymes with widespread occurrence in animals and plants. In humans, they catalyze phase I metabolism reactions,…”
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