Search Results - "Oliveira, Alaíde Braga"
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Plant-derived antimalarial agents: new leads and efficient phytomedicines. Part II. Non-alkaloidal natural products
Published in Molecules (13-08-2009)“…Malaria is still the most destructive and dangerous parasitic infection in many tropical and subtropical countries. The burden of this disease is getting…”
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In Vitro and in Vivo Antimalarial Activity, Cytotoxicity and Phytochemical HRMS2 Profile of Plants from the Western Pará State, Brazilian Amazonia
Published in Chemistry & biodiversity (01-01-2024)“…Ethnopharmacology and botanical taxonomy are valid criteria used to selecting plants for antimalarial bioprospection purposes. Based on these two criteria,…”
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Quinolinotriazole antiplasmodials via click chemistry: synthesis and in vitro studies of 7-Chloroquinoline-based compounds
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2021)“…Malaria is nowadays one of the most serious health concerns in a global scale and, although there is an evident increase in research studies in this area,…”
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Antiviral activity and chemical characterization of Cissus erosa (Vitaceae) ethanol extracts
Published in Rodriguésia (01-07-2020)“…Abstract Cissus erosa (Vitaceae), popularly known in Brazil as Cipó-fogo, is a medicinal plant used in the treatment of warts and external ulcers. The present…”
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Anatomy, Ultrastructure and Chemical Composition of Food Bodies of Hovenia dulcis (Rhamnaceae)
Published in Annals of botany (01-06-2008)“…BACKGROUND AND AIMS: Food bodies (FBs) are structures that promote mutualism between plants and ants, which help protect them against herbivores. The present…”
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Antiplasmodial activity and cytotoxicity, isolation of active alkaloids, and dereplication of Xylopia sericea leaves ethanol extract by UPLC‐DAD‐ESI‐MS/MS
Published in Journal of pharmacy and pharmacology (01-02-2019)“…Objectives To assess the antiplasmodial activity of the ethanol extract of Xylopia sericea leaves, Annonaceae, often associated with antimalarial use and to…”
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Occurrence, biological activities and synthesis of kaurane diterpenes and their glycosides
Published in Molecules (13-03-2007)“…This paper presents a review on kaurane diterpenes and their glycoside derivatives, covering aspects of their occurrence, biological activities and the…”
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In vitro antiplasmodial activity, targeted LC–MS metabolite profiling, and identification of major natural products in the bioactive extracts of Palicourea and Psychotria species from the Amazonia and Atlantic Forest biomes, Brazil
Published in Metabolomics (01-09-2021)“…Introduction A great variety of bioactive natural products has been reported for different Palicourea and Psychotria species (Rubiaceae). However, few of them…”
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Identification of phenolic compounds and biologically related activities from Ocotea odorifera aqueous extract leaves
Published in Food chemistry (01-09-2017)“…•Antioxidant, antibacterial and antimutagenic activity of Ocotea odorifera leaves.•Rapid identification of bioactive flavonoids and tannins via…”
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High-Resolution Mass Spectrometry Identification and Characterization of Flavonoids from Fridericia chica Leaves Extract with Anti-Arbovirus Activity
Published in Molecules (Basel, Switzerland) (16-09-2022)“…Plant extracts are complex mixtures that are difficult to characterize, and mass spectrometry is one of the main techniques currently used in dereplication…”
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Phytochemistry and antiplasmodial activity of Xylopia sericea leaves
Published in Natural product research (16-12-2020)“…Aiming to investigate the antiplasmodial activity and the phytochemical composition of Xylopia sericea leaves, the essential oil and dichloromethane extract…”
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A Comprehensive View on (−)‐7‐Oxo‐ent‐kaur‐16‐en‐19‐oic Acid, the Major Constituent of Xylopia sericea Leaves Extract: Complete NMR Assignments, X‐Ray Crystallographic Structure, in Vitro Antimalarial Activity and Cytotoxicity
Published in Chemistry & biodiversity (01-07-2019)“…Bioguided fractionation of Xylopia sericea antiplasmodial dichloromethane leaves extract led to the isolation of (−)‐7‐oxo‐ent‐kaur‐16‐en‐19‐oic acid…”
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13
Chemistry and Antiviral Activity of Arrabidaea pulchra (Bignoniaceae)
Published in Molecules (Basel, Switzerland) (16-08-2013)“…The aim of the present work was to carry out a bioguided isolation of antiviral chemical constituents from an ethanol extract of leaves from Arrabidaea pulchra…”
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Structure-based drug design studies of the interactions of ent-kaurane diterpenes derived from Wedelia paludosa with the Plasmodium falciparum sarco/endoplasmic reticulum Ca2+-ATPase PfATP6
Published in Memórias do Instituto Oswaldo Cruz (01-04-2015)“…Malaria is responsible for more deaths around the world than any other parasitic disease. Due to the emergence of strains that are resistant to the current…”
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Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits
Published in Journal of tropical medicine (01-01-2017)“…A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial…”
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Bioprospection for antiplasmodial activity, and identification of bioactive metabolites of native plants species from the Mata Atlântica biome, Brazil
Published in Natural product research (19-05-2021)“…A total of 33 extracts of eleven different plants species from Mata Atlântica biome, Brazil, and different fractions of the bioactive extracts were evaluated…”
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Aspidosperma species as sources of anti-malarials: uleine is the major anti-malarial indole alkaloid from Aspidosperma parvifolium (Apocynaceae)
Published in Malaria journal (10-12-2015)“…Several species of the genus Aspidosperma (Apocynaceae) are used for the treatment of human malaria in Brazil and other meso- and South American countries…”
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Antiviral Activity of Fridericia formosa (Bureau) L. G. Lohmann (Bignoniaceae) Extracts and Constituents
Published in Journal of tropical medicine (01-01-2017)“…A phytochemical study of Fridericia formosa (Bignoniaceae) ethanol extracts of leaves, stems, and fruits was guided by in vitro assays against vaccinia virus…”
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Mangifera indica leaves extract and mangiferin modulate CB1 and PPARγ receptors and others markers associated with obesity
Published in Journal of functional foods (01-05-2019)“…[Display omitted] •Phytochemical characterization of ethanolic extract of the leaves from Mangifera indica.•Analyzes with extract of M. indica and its isolated…”
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Antifungal constituents of Clytostoma ramentaceum and Mansoa hirsuta
Published in Phytotherapy research (01-06-2004)“…Ethanol extracts of Clytostoma ramentaceum Bur. & K. Schum and Mansoa hirsuta DC. (Bignoniaceae) inhibited the growth of standardized cultures of Aspergillus…”
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