Search Results - "Olivares, Eileen"

Ultrafast Au(III)-Mediated Arylation of Cysteine by Doud, Evan A., Tilden, James A. R., Treacy, Joseph W., Chao, Elaine Y., Montgomery, Hayden R., Kunkel, Grace E., Olivares, Eileen J., Adhami, Nima, Kerr, Tyler A., Chen, Yu, Rheingold, Arnold L., Loo, Joseph A., Frost, Christopher G., Houk, K. N., Maynard, Heather D., Spokoyny, Alexander M.

“…Through mechanistic work and rational design, we have developed the fastest organometallic abiotic Cys bioconjugation. As a result, the developed…”
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Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils by Abskharon, Romany, Pan, Hope, Sawaya, Michael R, Seidler, Paul M, Olivares, Eileen J, Chen, Yu, Murray, Kevin A, Zhang, Jeffrey, Lantz, Carter, Bentzel, Megan, Boyer, David R, Cascio, Duilio, Nguyen, Binh A, Hou, Ke, Cheng, Xinyi, Pardon, Els, Williams, Christopher K, Nana, Alissa L, Vinters, Harry V, Spina, Salvatore, Grinberg, Lea T, Seeley, William W, Steyaert, Jan, Glabe, Charles G, Ogorzalek Loo, Rachel R, Loo, Joseph A, Eisenberg, David S

“…Despite much effort, antibody therapies for Alzheimer's disease (AD) have shown limited efficacy. Challenges to the rational design of effective antibodies…”
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Amyloidogenicity of naturally occurring full‐length animal IAPP variants by Palato, Larry M., Pilcher, Shannon, Oakes, Alissa, Lamba, Arleen, Torres, Jaris, Ledesma Monjaraz, Litza I., Munoz, Crystabel, Njoo, Edward, Rinauro, Dillon J., Menefee, Kate Alexandra, Tun, Angela, Jauregui, Betssy L., Shapiro, Sarah, Nossiff, Olivia H., Olivares, Eileen, Chang, Kevin, Nguyen, Viviane, Nogaj, Luiza A., Moffet, David A.

“…The aggregation of the 37‐amino acid polypeptide human islet amyloid polypeptide (hIAPP), as either insoluble amyloid or as small oligomers, appears to play a…”
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