Search Results - "Olga Tarasova"

Current Perspectives in Antiviral Research by Tarasova, Olga A

“…Studies on virus–host interactions are of high significance for a number of reasons [...]…”
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Machine Learning in Discovery of New Antivirals and Optimization of Viral Infections Therapy by Tarasova, Olga, Poroikov, Vladimir

“…Nowadays, computational approaches play an important role in the design of new drug-like compounds and optimization of pharmacotherapeutic treatment of…”
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Changes in Endothelial Nitric Oxide Production in Systemic Vessels during Early Ontogenesis-A Key Mechanism for the Perinatal Adaptation of the Circulatory System by Gaynullina, Dina K, Schubert, Rudolf, Tarasova, Olga S

“…Nitric oxide (NO) produced in the wall of blood vessels is necessary for the regulation of vascular tone to ensure an adequate blood supply of organs and…”
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Molecular Docking Studies of HIV-1 Resistance to Reverse Transcriptase Inhibitors: Mini-Review by Tarasova, Olga, Poroikov, Vladimir, Veselovsky, Alexander

“…Currently, millions of people are living with human immunodeficiency virus type 1 (HIV-1), which causes acquired immunodeficiency syndrome. However, the spread…”
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Transcriptome-based analysis of human peripheral blood reveals regulators of immune response in different viral infections by Ivanov, Sergey M., Tarasova, Olga A., Poroikov, Vladimir V.

“…Introduction There are difficulties in creating direct antiviral drugs for all viruses, including new, suddenly arising infections, such as COVID-19…”
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Myography of isolated blood vessels: Considerations for experimental design and combination with supplementary techniques by Schubert, Rudolf, Gaynullina, Dina, Shvetsova, Anastasia, Tarasova, Olga S

“…The study of the mechanisms of regulation of vascular tone is an urgent task of modern science, since diseases of the cardiovascular system remain the main…”
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A Computational Approach for the Prediction of HIV Resistance Based on Amino Acid and Nucleotide Descriptors by Tarasova, Olga, Biziukova, Nadezhda, Filimonov, Dmitry, Poroikov, Vladimir

“…The high variability of the human immunodeficiency virus (HIV) is an important cause of HIV resistance to reverse transcriptase and protease inhibitors. There…”
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Viral Factors in Modulation of Host Immune Response: A Route to Novel Antiviral Agents and New Therapeutic Approaches by Tarasova, Olga, Petrou, Anthi, Ivanov, Sergey M, Geronikaki, Athina, Poroikov, Vladimir

“…Viruses utilize host cells at all stages of their life cycle, from the transcription of genes and translation of viral proteins to the release of viral copies…”
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The Effects of Acidosis on eNOS in the Systemic Vasculature: A Focus on Early Postnatal Ontogenesis by Gaynullina, Dina K, Tarasova, Olga S, Shvetsova, Anastasia A, Borzykh, Anna A, Schubert, Rudolf

“…The activity of many vasomotor signaling pathways strongly depends on extracellular/intracellular pH. Nitric oxide (NO) is one of the most important…”
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Network-Based Analysis of OMICs Data to Understand the HIV–Host Interaction by Ivanov, Sergey, Lagunin, Alexey, Filimonov, Dmitry, Tarasova, Olga

“…The interaction of human immunodeficiency virus with human cells is responsible for all stages of the viral life cycle, from the infection of CD4+ cells to…”
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Is It Possible to Predict a Forest Insect Outbreak? Backtesting Using Remote Sensing Data by Anton Kovalev, Olga Tarasova, Vladislav Soukhovolsky, Yulia Ivanova

“…In this study, methods are proposed for analyzing the susceptibility of forest stands to attacks by forest insects on the basis of Earth remote sensing data…”
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Bone marrow- and subcutaneous adipose tissue-derived mesenchymal stem cells: Differences and similarities by Dmitrieva, Renata I., Minullina, Izida R., Bilibina, Anna A., Tarasova, Olga V., Anisimov, Sergey V., Zaritskey, Andrey Y.

“…Bone marrow (BM) and subcutaneous adipose tissue (Ad) are both considered being prospective sources of MSC for therapeutic applications. However, functional…”
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CLC-Pred 2.0: A Freely Available Web Application for In Silico Prediction of Human Cell Line Cytotoxicity and Molecular Mechanisms of Action for Druglike Compounds by Lagunin, Alexey A, Rudik, Anastasia V, Pogodin, Pavel V, Savosina, Polina I, Tarasova, Olga A, Dmitriev, Alexander V, Ivanov, Sergey M, Biziukova, Nadezhda Y, Druzhilovskiy, Dmitry S, Filimonov, Dmitry A, Poroikov, Vladimir V

“…In vitro cell-line cytotoxicity is widely used in the experimental studies of potential antineoplastic agents and evaluation of safety in drug discovery. In…”
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Forest Insect Outbreak Dynamics: Fractal Properties, Viscous Fingers, and Holographic Principle by Vladislav Soukhovolsky, Anton Kovalev, Olga Tarasova, Yulia Ivanova

“…During the growth of a forest insect outbreak epicenter, there are processes that involve the formation and expansion of the primary epicenter of forest…”
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Remodeling of Arterial Tone Regulation in Postnatal Development: Focus on Smooth Muscle Cell Potassium Channels by Shvetsova, Anastasia A., Gaynullina, Dina K., Tarasova, Olga S., Schubert, Rudolf

“…Maturation of the cardiovascular system is associated with crucial structural and functional remodeling. Thickening of the arterial wall, maturation of the…”
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Negative feedback regulation of vasocontraction by potassium channels in 10‐ to 15‐day‐old rats: Dominating role of Kv7 channels by Shvetsova, Anastasia A., Gaynullina, Dina K., Tarasova, Olga S., Schubert, Rudolf

“…Aim Potassium channels are key regulators of smooth muscle membrane potential and arterial tone. However, the roles of potassium channels in vascular tone…”
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Pannexin 1 facilitates arterial relaxation via an endothelium-derived hyperpolarization mechanism by Gaynullina, Dina, Shestopalov, Valery I., Panchin, Yury, Tarasova, Olga S.

“…•We studied endothelium-dependent relaxations in control (WT) and Panx1−/− (KO) mice.•The EDH-like component of endothelium-dependent relaxation is impaired in…”
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Data and Text Mining Help Identify Key Proteins Involved in the Molecular Mechanisms Shared by SARS-CoV-2 and HIV-1 by Tarasova, Olga, Ivanov, Sergey, Filimonov, Dmitry A, Poroikov, Vladimir

“…Viruses can be spread from one person to another; therefore, they may cause disorders in many people, sometimes leading to epidemics and even pandemics. New,…”
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Exploring Scoring Function Space: Developing Computational Models for Drug Discovery by Bitencourt-Ferreira, Gabriela, Villarreal, Marcos A, Quiroga, Rodrigo, Biziukova, Nadezhda, Poroikov, Vladimir, Tarasova, Olga, de Azevedo Junior, Walter F

“…The idea of scoring function space established a systems-level approach to address the development of models to predict the affinity of drug molecules by those…”
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Reactive oxygen species augment contractile responses of saphenous artery in 10-15-day-old but not adult rats: Substantial role of NADPH oxidases by Shvetsova, Anastasia A., Khlystova, Margarita A., Makukha, Yulia A., Shateeva, Valentina S., Borzykh, Anna A., Gaynullina, Dina K., Tarasova, Olga S.

“…Reactive oxygen species (ROS) produced by NADPH oxidases (NOX, a key source of ROS in vascular cells) are involved in the regulation of vascular tone, but this…”
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