Search Results - "Olfert, I. Mark"
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Advances and challenges in skeletal muscle angiogenesis
Published in American journal of physiology. Heart and circulatory physiology (01-02-2016)“…The role of capillaries is to serve as the interface for delivery of oxygen and removal of metabolites to/from tissues. During the past decade there has been a…”
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An electron paramagnetic resonance time‐course study of oxidative stress in the plasma of electronic cigarette exposed rats
Published in Experimental physiology (01-09-2024)“…The long‐term consequences of electronic cigarette (Ecig) use in humans are not yet known, but it is known that Ecig aerosols contain many toxic compounds of…”
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Physiological Capillary Regression is not Dependent on Reducing VEGF Expression
Published in Microcirculation (New York, N.Y. 1994) (01-02-2016)“…Investigations into physiologically controlled capillary regression report the provocative finding that microvessel regression occurs in the face of persistent…”
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Aerobic exercise training reduces arterial stiffness in metabolic syndrome
Published in Journal of applied physiology (1985) (01-06-2014)“…The metabolic syndrome (MetS) is associated with a threefold increase risk of cardiovascular disease (CVD) mortality partly due to increased arterial…”
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Effect of chronic stress on running wheel activity in mice
Published in PloS one (19-09-2017)“…Acute and chronic stress have been reported to have differing effects on physical activity in rodents, but no study has examined a chronic stress protocol that…”
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Nicotine and Microvascular Responses in Skeletal Muscle from Acute Exposure to Cigarettes and Vaping
Published in International journal of molecular sciences (01-06-2023)“…Despite claims of safety or harm reduction for electronic cigarettes (E-cig) use (also known as vaping), emerging evidence indicates that E-cigs are not likely…”
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Temporal response of positive and negative regulators in response to acute and chronic exercise training in mice
Published in The Journal of physiology (15-10-2013)“…Key points • Angiogenic regulators respond to acute exercise with different temporal expression patterns (e.g. 2–4 h versus 12–24 h) creating a complex…”
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Muscle-specific VEGF deficiency greatly reduces exercise endurance in mice
Published in The Journal of physiology (15-04-2009)“…Vascular endothelial growth factor (VEGF) is required for vasculogenesis and angiogenesis during embryonic and early postnatal life. However the organ-specific…”
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Importance of Anti-angiogenic Factors in the Regulation of Skeletal Muscle Angiogenesis
Published in Microcirculation (New York, N.Y. 1994) (01-05-2011)“…Please cite this paper as: Olfert and Birot (2011). Importance of Anti‐angiogenic Factors in the Regulation of Skeletal Muscle Angiogenesis…”
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Functional deficiencies of subsarcolemmal mitochondria in the type 2 diabetic human heart
Published in American journal of physiology. Heart and circulatory physiology (01-07-2014)“…The mitochondrion has been implicated in the development of diabetic cardiomyopathy. Examination of cardiac mitochondria is complicated by the existence of…”
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Myocyte vascular endothelial growth factor is required for exercise-induced skeletal muscle angiogenesis
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-10-2010)“…We have previously shown, using a Cre-LoxP strategy, that vascular endothelial growth factor (VEGF) is required for the development and maintenance of skeletal…”
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Global deletion of thrombospondin-1 increases cardiac and skeletal muscle capillarity and exercise capacity in mice
Published in Experimental physiology (01-06-2009)“…Thrombospondin-1 (TSP-1) is a known inhibitor of angiogenesis; however, a skeletal muscle phenotype of TSP-1 null mice has not been investigated. The purposes…”
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Short-term exposure of female BALB/cJ mice to e-cigarette aerosol promotes neutrophil recruitment and enhances neutrophil-platelet aggregation in pulmonary microvasculature
Published in Journal of Toxicology and Environmental Health, Part A (18-04-2023)“…Despite the perception that e-cigarettes are safer than conventional cigarettes, numerous findings demonstrated that e-cigarette aerosol (EC) exposure induced…”
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Respiratory muscle training positively affects vasomotor response in young healthy women
Published in PloS one (25-09-2018)“…Vasomotor response is related to the capacity of the vessel to maintain vascular tone within a narrow range. Two main control mechanisms are involved: the…”
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Hypoxic Preconditioning Attenuates Reoxygenation-Induced Skeletal Muscle Dysfunction in Aged Pulmonary TNF-α Overexpressing Mice
Published in Frontiers in physiology (21-12-2018)“…Skeletal muscle subjected to hypoxia followed by reoxygenation is susceptible to injury and subsequent muscle function decline. This phenomenon can be observed…”
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Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
Published in Physiological reports (01-09-2021)“…Skeletal muscle anatomy and physiology are sexually dimorphic but molecular underpinnings and muscle‐specificity are not well‐established. Variances in…”
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Exercise training prevents the perivascular adipose tissue-induced aortic dysfunction with metabolic syndrome
Published in Redox biology (01-09-2019)“…The aim of the study was to determine the effects of exercise training on improving the thoracic perivascular adipose tissue (tPVAT) phenotype (inflammation,…”
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Effects of detraining on the temporal expression of positive and negative angioregulatory proteins in skeletal muscle of mice
Published in The Journal of physiology (01-08-2014)“…Key points Skeletal muscle capillary regression is associated with elevated thrombospondin‐1 and vascular endothelial growth factor protein expression with…”
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High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer
Published in Cancers (26-06-2015)“…Epidemiological studies provide strong evidence that obesity and the associated adipose tissue inflammation are risk factors for breast cancer; however, the…”
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