Search Results - "Olek, Robert A"

The bright and the dark sides of L-carnitine supplementation: a systematic review by Sawicka, Angelika K, Renzi, Gianluca, Olek, Robert A

“…L-carnitine (LC) is used as a supplement by recreationally-active, competitive and highly trained athletes. This systematic review aims to evaluate the effect…”
Get full text

A Pilot Study on the Effects of l-Carnitine and Trimethylamine-N-Oxide on Platelet Mitochondrial DNA Methylation and CVD Biomarkers in Aged Women by Bordoni, Laura, Sawicka, Angelika K, Szarmach, Arkadiusz, Winklewski, Pawel J, Olek, Robert A, Gabbianelli, Rosita

“…l-carnitine supplementation has been used for cardiovascular health protection for a long time. Recently, trimethylamine-N-oxide (TMAO), which is an end…”
Get full text

Current knowledge about pyruvate supplementation: A brief review by Olek, Robert A., Kujach, Sylwester, Radak, Zsolt

“…Pyruvate is a three-carbon ketoacid that occurs naturally in cells. It is produced through enzymatic reactions in the glycolytic pathway and plays a crucial…”
Get full text

Effect of a 3-month L-carnitine supplementation and resistance training program on circulating markers and bone mineral density in postmenopausal women: a randomized controlled trial by Olek, Robert A, Samborowska, Emilia, Wisniewski, Piotr, Wojtkiewicz, Pawel, Wochna, Krystian, Zielinski, Jacek

“…Higher circulating levels of trimethylamine N-oxide (TMAO), which is a metabolite that can be produced by the gut microbiota from L-carnitine (LC), have been…”
Get full text

Changes on fecal microbiota in rats exposed to permethrin during postnatal development by Nasuti, Cinzia, Coman, Maria Magdalena, Olek, Robert A., Fiorini, Dennis, Verdenelli, Maria Cristina, Cecchini, Cinzia, Silvi, Stefania, Fedeli, Donatella, Gabbianelli, Rosita

“…Alteration of the gut microbiota through diet and environmental contaminants may disturb the mammalian digestive system, leading to various diseases. Because…”
Get full text

L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women by Samulak, Joanna J, Sawicka, Angelika K, Hartmane, Dace, Grinberga, Solveiga, Pugovics, Osvalds, Lysiak-Szydlowska, Wieslawa, Olek, Robert A

“…L-carnitine can be metabolized to trimethylamine N-oxide (TMAO), a molecule that promotes atherogenesis through its interaction with macrophages and lipid…”
Get more information

Plasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged Women by Samulak, Joanna J, Sawicka, Angelika K, Samborowska, Emilia, Olek, Robert A

“…L-carnitine supplementation elevates plasma trimethylamine-N-oxide (TMAO), which may participate in atherosclerosis development by affecting cholesterol…”
Get full text

l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function by Sawicka, Angelika K, Hartmane, Dace, Lipinska, Patrycja, Wojtowicz, Ewa, Lysiak-Szydlowska, Wieslawa, Olek, Robert A

“…Skeletal muscle wasting, associated with aging, may be regulated by the inflammatory cytokines as well as by insulin-like growth factor 1 (IGF-1). l-carnitine…”
Get full text

Adaptive Changes After 2 Weeks of 10-s Sprint Interval Training With Various Recovery Times by Olek, Robert A, Kujach, Sylwester, Ziemann, Ewa, Ziolkowski, Wieslaw, Waz, Piotr, Laskowski, Radoslaw

“…The aim of this study was to compare the effect of applying two different rest recovery times in a 10-s sprint interval training session on aerobic and…”
Get full text

Whole-body cryostimulation as an effective method of reducing low-grade inflammation in obese men by Ziemann, Ewa, Olek, Robert A, Grzywacz, Tomasz, Antosiewicz, Jędrzej, Kujach, Sylwester, Łuszczyk, Marcin, Smaruj, Mirosław, Sledziewska, Ewelina, Laskowski, Radosław

“…This study was aimed to evaluate anti-inflammatory effect of the whole body cryostimulation in obese men. Fourteen subjects (BMI >30 kg m(-2)), divided into…”
Get full text

Single pyruvate intake induces blood alkalization and modification of resting metabolism in humans by Olek, Robert A., Ph.D, Luszczyk, Marcin, Ph.D, Kujach, Sylwester, M.Sc, Ziemann, Ewa, Ph.D, Pieszko, Magdalena, Ph.D, Pischel, Ivo, Ph.D, Laskowski, Radoslaw, Ph.D

“…Abstract Objectives Three separate studies were performed with the aim to 1) determine the effect of a single sodium pyruvate intake on the blood acid-base…”
Get full text

Oral Administration of Sodium Nitrate to Metabolic Syndrome Patients Attenuates Mild Inflammatory and Oxidative Responses to Acute Exercise by Capó, Xavier, Ferrer, Miguel D., Olek, Robert A., Salaberry, Eduardo, Suau, Rafael, Marí, Bartolomé, Llompart, Isabel, Tur, Josep A., Sureda, Antoni, Pons, Antoni

“…The beneficial effects of exercise for the treatment and prevention of metabolic syndrome pathologies have been related to its anti-inflammatory and…”
Get full text

Single sodium pyruvate ingestion modifies blood acid-base status and post-exercise lactate concentration in humans by Olek, Robert A, Kujach, Sylwester, Wnuk, Damian, Laskowski, Radoslaw

“…This study examined the effect of a single sodium pyruvate ingestion on a blood acid-base status and exercise metabolism markers. Nine active, but…”
Get full text

Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients by Bordoni, Laura, Fedeli, Donatella, Piangerelli, Marco, Pelikant-Malecka, Iwona, Radulska, Adrianna, Samulak, Joanna J., Sawicka, Angelika K., Lewicki, Lukasz, Kalinowski, Leszek, Olek, Robert A., Gabbianelli, Rosita

“…Gender differences in the burden of cardiovascular disease (CVD) have been observed worldwide. In this study, plasmatic levels of trimethylamine (TMA) and…”
Get full text

Twenty-Four Weeks of L-Carnitine Combined with Leucine Supplementation Does Not Increase the Muscle Carnitine Content in Healthy Active Subjects by Samborowska, Emilia, Olek, Robert A

“…To increase the total carnitine (TC) content in muscles, L-carnitine (LC) should be co-ingested with carbohydrates to induce an insulin response. Leucine has…”
Get more information

Effect of ethyl pyruvate on skeletal muscle metabolism in rats fed on a high fat diet by Olek, Robert A, Ziolkowski, Wieslaw, Wierzba, Tomasz H, Kaczor, Jan J

“…Impaired mitochondrial capacity may be implicated in the pathology of chronic metabolic diseases. To elucidate the effect of ethyl pyruvate supplementation on…”
Get full text

Mitochondrial DNA copy number and trimethylamine levels in the blood: New insights on cardiovascular disease biomarkers by Bordoni, Laura, Petracci, Irene, Pelikant‐Malecka, Iwona, Radulska, Adriana, Piangerelli, Marco, Samulak, Joanna J., Lewicki, Lukasz, Kalinowski, Leszek, Gabbianelli, Rosita, Olek, Robert A.

“…Among cardiovascular disease (CVD) biomarkers, the mitochondrial DNA copy number (mtDNAcn) is a promising candidate. A growing attention has been also…”
Get full text

Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study by Bordoni, Laura, Samulak, Joanna J., Sawicka, Angelika K., Pelikant-Malecka, Iwona, Radulska, Adrianna, Lewicki, Lukasz, Kalinowski, Leszek, Gabbianelli, Rosita, Olek, Robert A.

“…The early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol…”
Get full text

Protective effect of ethyl pyruvate on msP rat leukocytes damaged by alcohol intake by Fedeli, Donatella, Falcioni, Giancarlo, Olek, Robert A., Massi, Maurizio, Cifani, Carlo, Polidori, Carlo, Gabbianelli, Rosita

“…Alcohol consumption for long periods negatively influences physiological functions of many cells, and leads to organ damage. Reactive oxygen and nitrogen…”
Get full text

L-Carnitine Combined with Leucine Supplementation Does Not Improve the Effectiveness of Progressive Resistance Training in Healthy Aged Women by Sawicka, A. K., Jaworska, J., Brzeska, B., Sabisz, A., Samborowska, E., Radkiewicz, M., Szurowska, E., Winklewski, P. J., Szarmach, A., Olek, Robert A.

“…Objectives To evaluate the effect of L-carnitine (LC) in combination with leucine supplementation on muscle strength and muscle hypertrophy in aged women…”
Get full text