Search Results - "Olejniczak, Sylwia"

The Interplay between Gut Microbiota and Cognitive Functioning in the Healthy Aging Population: A Systematic Review by Kossowska, Maria, Olejniczak, Sylwia, Karbowiak, Marcelina, Mosiej, Wioletta, Zielińska, Dorota, Brzezicka, Aneta

“…The gut microbiota in healthy older individuals typically show a decrease in beneficial bacteria like Bifidobacterium and Lactobacillus, alongside an increase…”
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Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma by Mazur, Marzena, Olczak, Jacek, Olejniczak, Sylwia, Koralewski, Robert, Czestkowski, Wojciech, Jedrzejczak, Anna, Golab, Jakub, Dzwonek, Karolina, Dymek, Barbara, Sklepkiewicz, Piotr L, Zagozdzon, Agnieszka, Noonan, Tom, Mahboubi, Keyvan, Conway, Bruce, Sheeler, Ryan, Beckett, Paul, Hungerford, William M, Podjarny, Alberto, Mitschler, Andre, Cousido-Siah, Alexandra, Fadel, Firas, Golebiowski, Adam

“…This article highlights our work toward the identification of a potent, selective, and efficacious acidic mammalian chitinase (AMCase) inhibitor. Rational…”
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Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase by Mazur, Marzena, Bartoszewicz, Agnieszka, Dymek, Barbara, Salamon, Magdalena, Andryianau, Gleb, Kowalski, Michał, Olejniczak, Sylwia, Matyszewski, Krzysztof, Pluta, Elżbieta, Borek, Bartłomiej, Stefaniak, Filip, Zagozdzon, Agnieszka, Mazurkiewicz, Marcin, Koralewski, Robert, Czestkowski, Wojciech, Piotrowicz, Michał, Niedziejko, Piotr, Gruza, Mariusz M., Dzwonek, Karolina, Golebiowski, Adam, Golab, Jakub, Olczak, Jacek

“…[Display omitted] This article describes our work towards the identification of a potent and selective inhibitor of mouse chitotriosidase (mCHIT1). A series of…”
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Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis by Koralewski, Robert, Dymek, Barbara, Mazur, Marzena, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Czestkowski, Wojciech, Matyszewski, Krzysztof, Andryianau, Gleb, Niedziejko, Piotr, Kowalski, Michal, Gruza, Mariusz, Borek, Bartłomiej, Jedrzejczak, Karol, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Kania, Magdalena, Rejczak, Tomasz, Piasecka, Sylwia, Mlacki, Michal, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Agnieszka, Bartlomiejczak, Aneta, Mozga, Witold, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Nowotny, Marcin, Olczak, Jacek, Golebiowski, Adam

“…Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic…”
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Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1 by Czestkowski, Wojciech, Krzemiński, Łukasz, Piotrowicz, Michał C., Mazur, Marzena, Pluta, Elżbieta, Andryianau, Gleb, Koralewski, Robert, Matyszewski, Krzysztof, Olejniczak, Sylwia, Kowalski, Michał, Lisiecka, Katarzyna, Kozieł, Rafał, Piwowar, Katarzyna, Papiernik, Diana, Nowotny, Marcin, Napiórkowska-Gromadzka, Agnieszka, Nowak, Elżbieta, Niedziałek, Dorota, Wieczorek, Grzegorz, Siwińska, Anna, Rejczak, Tomasz, Jędrzejczak, Karol, Mulewski, Krzysztof, Olczak, Jacek, Zasłona, Zbigniew, Gołębiowski, Adam, Drzewicka, Katarzyna, Bartoszewicz, Agnieszka

“…Chitinase-3-like-1 (CHI3L1), also known as YKL-40, is a glycoprotein linked to inflammation, fibrosis, and cancer. This study explored CHI3L1’s interactions…”
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Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases by Mazur, Marzena, Dymek, Barbara, Koralewski, Robert, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Jędrzejczak, Karol, Zagozdzon, Agnieszka, Czestkowski, Wojciech, Matyszewski, Krzysztof, Borek, Bartłomiej, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Mozga, Witold, Stefaniak, Filip, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Golebiowski, Adam, Olczak, Jacek

“…Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals capable of cleaving the glycosidic…”
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A New Inhibitor of Tubulin Polymerization Kills Multiple Cancer Cell Types and Reveals p21-Mediated Mechanism Determining Cell Death after Mitotic Catastrophe by Zdioruk, Mykola, Want, Andrew, Mietelska-Porowska, Anna, Laskowska-Kaszub, Katarzyna, Wojsiat, Joanna, Klejman, Agata, Użarowska, Ewelina, Koza, Paulina, Olejniczak, Sylwia, Pikul, Stanislaw, Konopka, Witold, Golab, Jakub, Wojda, Urszula

“…Induction of mitotic catastrophe through the disruption of microtubules is an established target in cancer therapy. However, the molecular mechanisms…”
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Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase by Andryianau, Gleb, Kowalski, Michal, Piotrowicz, Michal C., Rajkiewicz, Adam A., Dymek, Barbara, Sklepkiewicz, Piotr L., Pluta, Elzbieta, Stefaniak, Filip, Czestkowski, Wojciech, Olejniczak, Sylwia, Mazur, Marzena, Niedziejko, Piotr, Koralewski, Robert, Matyszewski, Krzysztof, Gruza, Mariusz, Zagozdzon, Agnieszka, Salamon, Magdalena, Rymaszewska, Aleksandra, Welzer, Mikolaj, Dzwonek, Karolina, Golab, Jakub, Olczak, Jacek, Bartoszewicz, Agnieszka, Golebiowski, Adam

“…Human acidic mammalian chitinase (hAMCase) is one of two true chitinases in humans, the function of which remains elusive. In addition to the defense against…”
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