Search Results - "Olee, T."

Functional analyses of patient-derived IgG monoclonal anticardiolipin antibodies using in vivo thrombosis and in vivo microcirculation models by Pierangeli, S S, Liu, X, Espinola, R, Olee, T, Zhu, M, Harris, N E, Chen, P P

“…Antiphospholipid antibodies (aPL) have been associated with thrombosis and pregnancy losses in patients diagnosed with antiphospholipid syndrome (APS) and…”
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A Monoclonal IgG Anticardiolipin Antibody from a Patient with the Antiphospholipid Syndrome is Thrombogenic in Mice by Olee, Tsaiwei, Pierangeli, Silvia S., Handley, Harold H., Le, Dzung T., Wei, Xin, Lai, Chung-Jeng, En, Julie, Novotny, William, Harris, E. Nigel, Woods, Virgil L., Chen, Pojen P.

“…Antiphospholipid antibodies, including anticardiolipin antibodies (ACA), are strongly associated with recurrent thrombosis in patients with the…”
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Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response by OLEE, T, LU, E. W, DE-FENG HUANG, SOTO-GIL, R. W, DEFTOS, M, KOZIN, F, CARSON, D. A, CHEN, P. P

“…Although much has been learned about the molecular basis of immunoglobulin M (IgM) rheumatoid factors (RFs) in healthy individuals and in patients with mixed…”
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Response of the axon and barrier endothelium to experimental allergic neuritis induced by autoreactive T cell lines by POWELL, H. C, MYERS, R. R, MIZISIN, A. P, OLEE, T, BROSTOFF, S. W

“…Experimental allergic neuritis was induced in Lewis rats by inoculation with autoreactive T cell lines sensitized to residue 57-81 of P2 myelin protein…”
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IL-18 Is Produced by Articular Chondrocytes and Induces Proinflammatory and Catabolic Responses by Olee, Tsaiwei, Hashimoto, Sanshiro, Quach, Jacqueline, Lotz, Martin

“…IL-18, a cytokine originally identified as IFN-gamma-inducing factor, is a member of the IL-1 family of proteins. Because IL-1alpha and IL-1beta are important…”
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Possible Deletion of a Developmentally Regulated Heavy-Chain Variable Region Gene in Autoimmune Diseases by Yang, Pei-Ming, Olsen, Nancy J., Siminovitch, Katherine A., Olee, Tsaiwei, Kozin, Franklin, Carson, Dennis A., Chen, Pojen P.

“…Several autoantibody-associated variable region (V) genes are preferentially expressed during early ontogenic development, suggesting strongly that they are of…”
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Genetic analysis of the variable region genes encoding a monospecific human natural anti‐DNA antibody by DALEY, M. D., MISENER, V., OLEE, T., CHEN, P. P., SIMINOVITCH, K. A.

“…SUMMARY Recent evidence suggests that natural autoantibodies may play an integral rote in the development of the normal immune repertoire. To explore the…”
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P127 TGFb3 MODULATES NOTCH-1 PROTEIN EXPRESSION LEVELS IN HUMAN ARTICULAR CHONDROCYTES AND MESENCHYMAL STEM CELLS by Grogan, S.P., Olee, T., Johnson, K.A., Terkeltaub, R.A., Lotz, M.K.

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Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein by Hörkkö, S, Olee, T, Mo, L, Branch, D W, Woods, Jr, V L, Palinski, W, Chen, P P, Witztum, J L

“…We recently suggested that many anticardiolipin antibodies bind only to oxidized cardiolipin (OxCL) and/or to OxCL-beta(2)-glycoprotein 1 (beta(2)GP1) adducts…”
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Vaccination against Experimental Allergic Encephalomyelitis with T Cell Receptor Peptides by Howell, Mark D., Winters, Steven T., Olee, Tsaiwei, Powell, Henry C., Carlo, Dennis J., Brostoff, Steven W.

“…Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system mediated by CD4$^{+}$ T cells reactive with myelin basic…”
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Bacterial lipopolysaccharide copurifies with plasmid DNA: implications for animal models and human gene therapy by Wicks, I P, Howell, M L, Hancock, T, Kohsaka, H, Olee, T, Carson, D A

“…During the course of gene therapy experiments in rodents, using intramuscular injections of plasmid DNA derived from Escherichia coli, we noted dose-related…”
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Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseases by OLEE, T, PEI-MING YANG, SIMINOVITCH, K. A, OLSEN, N. J, HILLSON, J, WU, J, KOZIN, F, CARSON, D. A, CHEN, P. P

“…Recently, combined serological and molecular studies of autoantibodies have revealed that these antibodies play an important role in the normal function of the…”
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The effects of aggregated human IgG and IgG-immune complexes on the agglutination of bacteria mediated by non-immunoglobulin salivary agglutinins by O'Lee, T W, Boackle, R J

“…Non-immunoglobulin salivary agglutinins (SBA) for bacteria which bind to Streptococcus milleri TJ7 were isolated from parotid saliva and their interactions…”
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Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors by Deftos, M, Olee, T, Carson, D A, Chen, P P

“…A major diagnostic marker in most rheumatoid arthritis (RA) patients is the rheumatoid factor (RF), an autoantibody that binds to the Fc region of IgG. To…”
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Population and family studies of three disease-related polymorphic genes in systemic lupus erythematosus by Huang, D F, Siminovitch, K A, Liu, X Y, Olee, T, Olsen, N J, Berry, C, Carson, D A, Chen, P P

“…The contribution to systemic lupus erythematosus (SLE) of three lupus-associated polymorphisms (involving the C4A2 complement component, Humhv3005 and the T…”
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Characterization of IgG monoclonal anti-cardiolipin/anti-beta2GP1 antibodies from two patients with antiphospholipid syndrome reveals three species of antibodies by Zhu, M, Olee, T, Le, D T, Roubey, R A, Hahn, B H, Woods, Jr, V L, Chen, P P

“…Antiphospholipid antibodies (aPL), including antibodies detected in anti-cardiolipin (aCL) enzyme-linked immunosorbent assays and in lupus anticoagulant (LA)…”
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Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not Vλ genes by DE-FENG HUANG, OLEE, T, MASUHO, Y, MATSUMOTO, Y.-I, CARSON, D. A, CHEN, P. P

“…Accumulated sequence analyses of the antibody repertoire have revealed that most autoantibodies and developmentally regulated antibodies share a small set of…”
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A T cell epitope for experimental allergic neuritis is an amphipathic alpha-helical structure by Olee, T, Weise, M, Powers, J, Brostoff, S

“…The bovine P2 protein is known to produce experimental allergic neuritis (EAN) in Lewis rats. The longest region of amphipathic alpha-helix within the bovine…”
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New minimum length requirement for a T cell epitope for experimental allergic neuritis by Olee, T, Powell, H C, Brostoff, S W

“…The bovine P2 protein induces experimental allergic neuritis (EAN) in Lewis rats. Using synthetic peptides representing regions of the P2 protein sequence and…”
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IgG rheumatoid factors isolated by the surface-displaying phage library technique by Yang, Y Y, Fischer, P, Leu, S J, Olee, T, Carson, D A, Chen, P P

“…Our analysis of IgG rheumatoid factors (RFs) from three patients with rheumatoid arthritis (RA) revealed that most contained significant numbers of skewed…”
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