Search Results - "Olech, Kamila"
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Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
Published in Scientific reports (06-06-2023)“…Proteases encoded by SARS-CoV-2 constitute a promising target for new therapies against COVID-19. SARS-CoV-2 main protease (M pro , 3CL pro ) and papain-like…”
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Optimized Ebselen-Based Inhibitors of Bacterial Ureases with Nontypical Mode of Action
Published in Journal of medicinal chemistry (09-02-2023)“…Screening of 25 analogs of Ebselen, diversified at the N-aromatic residue, led to the identification of the most potent inhibitors of Sporosarcina pasteurii…”
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Discovery of 5-{2-[5-Chloro-2-(5-ethoxyquinoline-8-sulfonamido)phenyl]ethynyl}-4-methoxypyridine-2-carboxylic Acid, a Highly Selective in Vivo Useable Chemical Probe to Dissect MCT4 Biology
Published in Journal of medicinal chemistry (26-08-2021)“…Due to increased lactate production during glucose metabolism, tumor cells heavily rely on efficient lactate transport to avoid intracellular lactate…”
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4
The Synthesis and Characterization of -3,4-Ethylenedioxythiophene Derivatives with Electroactive Features
Published in Electrochimica acta (20-09-2014)“…We report the synthesis of conjugated oligomers based on electron withdrawing 3,4-ethylenedioxythiophene (EDOT) in the case of which band gaps are tuned by the…”
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5
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PL pro and M pro proteases, and nsp14 guanine N7-methyltransferase
Published in Scientific reports (06-06-2023)“…Proteases encoded by SARS-CoV-2 constitute a promising target for new therapies against COVID-19. SARS-CoV-2 main protease (M , 3CL ) and papain-like protease…”
Get full text
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Synthesis and Electrochromic Properties of Conducting Polymers Based on Highly Planar 2,7-Disubstituted Xanthene Derivatives
Published in ChemPlusChem (Weinheim, Germany) (01-04-2015)“…On the basis of preliminary DFT calculations, p‐type semiconducting polymers based on 2,7‐substituted xanthene building blocks that show a high degree of…”
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Detecting platform for phenolic compoundsacharacteristic of enzymatic electrode
Published in Optical materials (01-08-2012)“…We report here on simple and universal method for the highly efficient, electrolytic immobilization of tyrosinase (from Agaricus bisporus), for amperometric…”
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Detecting platform for phenolic compounds–characteristic of enzymatic electrode
Published in Optical materials (01-08-2012)“…► We model an enzymatic electrode built as hybrid protein-copolymer on Pt electrode. ► We modify the Pt electrodes with conducting copolymer before enzyme…”
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Comparative Study of Alternating Low-band-Gap Benzothiadiazole Co-oligomers
Published in Journal of fluorescence (01-07-2011)“…The benzothiadiazole – arylene alternating conjugated oligomers have been designed and synthesized via Suzuki coupling reaction. The structures and properties…”
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