Search Results - "Olea Azar, Claudio"
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5‐Nitrofuryl‐Containing Thiosemicarbazone Gold(I) Compounds: Synthesis, Stability Studies, and Anticancer Activity
Published in ChemPlusChem (Weinheim, Germany) (01-12-2023)“…This work describes the synthesis of four gold(I) [AuClL] compounds containing chloro and biologically active protonated thiosemicarbazones based on…”
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2
Safety and Pharmacokinetics of a Combined Antioxidant Therapy against Myocardial Reperfusion Injury: A Phase 1 Randomized Clinical Trial in Healthy Humans
Published in Clinical pharmacology in drug development (01-09-2024)“…Myocardial reperfusion injury (MRI) accounts for up to 50% of the final size in acute myocardial infarction and other conditions associated with…”
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3
Mechanism of Anti-Trypanosoma cruzi Action of Gold(I) Compounds: A Theoretical and Experimental Approach
Published in Inorganics (01-05-2024)“…In the search for a more effective chemotherapy for the treatment of Chagas’ disease, caused by Trypanosoma cruzi parasite, the use of gold compounds may be a…”
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4
Inclusion and functionalization of polymers with cyclodextrins: current applications and future prospects
Published in Molecules (09-09-2014)“…The numerous hydroxyl groups available in cyclodextrins are active sites that can form different types of linkages. They can be crosslinked with one another,…”
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Morin Flavonoid Adsorbed on Mesoporous Silica, a Novel Antioxidant Nanomaterial
Published in PloS one (03-11-2016)“…Morin (2´,3, 4´,5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to…”
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Polyphenolic Composition and Antioxidant Activity (ORAC, EPR and Cellular) of Different Extracts of Argylia radiata Vitroplants and Natural Roots
Published in Molecules (Basel, Switzerland) (18-01-2022)“…Plant biochemistry studies have increased in recent years due to their potential to improve human health. is an extremophile plant with an interesting…”
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Dependence of the Ripeness Stage on the Antioxidant and Antimicrobial Properties of Walnut (Juglans regia L.) Green Husk Extracts from Industrial By-Products
Published in Molecules (Basel, Switzerland) (13-05-2021)“…Walnut green husk (WGH) is a waste generated by the walnut (Juglans regia L.) harvest industry. It represents a natural source of polyphenols, compounds with…”
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8
Synthesis and Electrochemical and Biological Studies of Novel Coumarin–Chalcone Hybrid Compounds
Published in Journal of medicinal chemistry (08-08-2013)“…A series of novel hydroxy-coumarin–chalcone hybrid compounds 2a–i has been synthesized by employing a simple and efficient methodology. An electrochemical…”
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9
Antioxidant Capacity and NF-kB-Mediated Anti-Inflammatory Activity of Six Red Uruguayan Grape Pomaces
Published in Molecules (Basel, Switzerland) (05-05-2023)“…Grape pomaces have a wide and diverse antioxidant phenolics composition. Six Uruguayan red grape pomaces were evaluated in their phenolics composition,…”
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10
Monoamine transporter inhibitors and norepinephrine reduce dopamine‐dependent iron toxicity in cells derived from the substantia nigra
Published in Journal of neurochemistry (01-03-2005)“…The role of dopamine in iron uptake into catecholaminergic neurons, and dopamine oxidation to aminochrome and its one‐electron reduction in iron‐mediated…”
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11
Microalgae extracts: Potential anti-Trypanosoma cruzi agents?
Published in Biomedicine & pharmacotherapy (01-07-2020)“…[Display omitted] •Chlamydomonas reinhardtii presents anti-Trypanosoma cruzi activity.•Scenedesmus obliquus presents anti-Trypanosoma cruzi…”
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12
5‐Nitrofuryl‐Containing Thiosemicarbazone Gold(I) Compounds: Synthesis, Stability Studies, and Anticancer Activity
Published in ChemPlusChem (Weinheim, Germany) (01-12-2023)“…Invited for this month's cover are the collaborating groups of Esteban Rodríguez‐Arce from the University of Chile and María Contel from The City University of…”
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Front Cover: 5‐Nitrofuryl‐Containing Thiosemicarbazone Gold(I) Compounds: Synthesis, Stability Studies, and Anticancer Activity (ChemPlusChem 12/2023)
Published in ChemPlusChem (Weinheim, Germany) (01-12-2023)“…“Supergold” is a very powerful gender‐neutral warrior with superpowers who fights against cancer! The warrior's golden armor and sword represent the…”
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14
Evaluation of ORAC methodologies in determination of antioxidant capacity of binary combinations of quercetin and 3-(3,4,5-trihydroxybenzoyl) coumarin derivatives
Published in Arabian journal of chemistry (01-11-2022)“…[Display omitted] Antioxidant capacity is used to refer to ability of compounds to react with free radicals, it is also described as ability to inhibit…”
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15
Synthesis and antioxidant study of new polyphenolic hybrid-coumarins
Published in Arabian journal of chemistry (01-05-2018)“…The antioxidant capacity of hydroxylated coumarins and hydroxybenzoic acids has been widely described. However, there is little information on the antioxidant…”
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16
Assessment of the Activity of Nitroisoxazole Derivatives against Trypanosoma cruzi
Published in Molecules (Basel, Switzerland) (11-06-2024)“…The development of new compounds to treat Chagas disease is imperative due to the adverse effects of current drugs and their low efficacy in the chronic phase…”
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17
Study of coumarin-resveratrol hybrids as potent antioxidant compounds
Published in Molecules (Basel, Switzerland) (16-02-2015)“…In the present work we synthesized a selected series of hydroxylated 3-phenylcoumarins 5-8, with the aim of evaluating in detail their antioxidant properties…”
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Synthesis of Silver Nanoparticles Using Aqueous Leaf Extract of Mimosa albida (Mimosoideae): Characterization and Antioxidant Activity
Published in Materials (21-01-2020)“…The search for sensitive and rapid analytical techniques for the determination of natural antioxidants is an area in constant growth due, among other aspects,…”
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19
Multi-target heteroleptic palladium bisphosphonate complexes
Published in Journal of biological inorganic chemistry (01-05-2020)“…Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis and other bone illnesses. Some of them have also shown antiparasitic…”
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Trypanocidal effect of alcoholic extract of Castanedia santamartensis (Asteraceae) leaves is based on altered mitochondrial function
Published in Biomedicine & pharmacotherapy (01-04-2022)“…The deficit of effective treatments for Chagas disease has led to searching for new substances with therapeutic potential. Natural products possess a wide…”
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