Search Results - "Oldroyd, Keith"
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Randomized Trial of Preventive Angioplasty in Myocardial Infarction
Published in The New England journal of medicine (19-09-2013)“…Patients with acute STEMI were randomly assigned to undergo infarct-vessel-only PCI or preventive PCI (PCI to noninfarct arteries with stenoses). The rate of…”
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Stratified Medical Therapy Using Invasive Coronary Function Testing in Angina: The CorMicA Trial
Published in Journal of the American College of Cardiology (11-12-2018)“…Patients with angina symptoms and/or signs of ischemia but no obstructive coronary artery disease (INOCA) pose a diagnostic and therapeutic challenge. The…”
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Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial
Published in The Lancet (British edition) (07-11-2015)“…Summary Background In the Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) study, fractional flow reserve (FFR)-guided percutaneous…”
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1-Year Outcomes of Angina Management Guided by Invasive Coronary Function Testing (CorMicA)
Published in JACC. Cardiovascular interventions (13-01-2020)“…The aim of this study was to test the hypothesis that invasive coronary function testing at time of angiography could help stratify management of angina…”
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Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments
Published in European heart journal (01-12-2015)“…Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the…”
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Prognostic Value and Risk Continuum of Noninvasive Fractional Flow Reserve Derived from Coronary CT Angiography
Published in Radiology (01-08-2019)“…Background Coronary CT angiography with noninvasive fractional flow reserve (FFR) predicts lesion-specific ischemia when compared with invasive FFR. The longer…”
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Meta-Analysis of Death and Myocardial Infarction in the DEFINE-FLAIR and iFR-SWEDEHEART Trials
Published in Circulation (New York, N.Y.) (12-12-2017)Get full text
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Complete Immediate Revascularization of the Patient With ST-Segment-Elevation Myocardial Infarction Is the New Standard of Care
Published in Circulation (New York, N.Y.) (25-04-2017)Get full text
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Diastolic pressure ratio: new approach and validation vs. the instantaneous wave-free ratio
Published in European heart journal (14-08-2019)“…Abstract Aims The instantaneous wave-free ratio (iFR) and whole-cycle Pd/Pa investigate coronary physiology during non-hyperaemic conditions. To test for…”
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Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR)
Published in European heart journal (01-12-2021)“…A fractional flow reserve (FFR) value ≥0.90 after percutaneous coronary intervention (PCI) is associated with a reduced risk of adverse cardiovascular events…”
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Comparison of Different Diastolic Resting Indexes to iFR: Are They All Equal?
Published in Journal of the American College of Cardiology (26-12-2017)“…Pressure measurement for the duration of the wave-free period (WFP) is considered essential for resting-state physiological assessment of coronary stenosis…”
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Performance of drug-coated balloons in coronary and below-the-knee arteries: Anatomical, physiological and pathological considerations
Published in Vascular pharmacology (01-06-2024)“…Below-the-knee (infrapopliteal) atherosclerotic disease, which presents as chronic limb-threatening ischemia (CLTI) in nearly 50% of patients, represents a…”
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Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction
Published in European heart journal (07-09-2020)“…Endothelin-1 (ET-1) is a potent vasoconstrictor peptide linked to vascular diseases through a common intronic gene enhancer [(rs9349379-G allele), chromosome 6…”
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Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation FAMOUS-NSTEMI randomized trial
Published in European heart journal (07-01-2015)“…We assessed the management and outcomes of non-ST segment elevation myocardial infarction (NSTEMI) patients randomly assigned to fractional flow reserve…”
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Prognostic Value of the Index of Microcirculatory Resistance Measured After Primary Percutaneous Coronary Intervention
Published in Circulation (New York, N.Y.) (18-06-2013)“…BACKGROUND—Most methods for assessing microvascular function are not readily available in the cardiac catheterization laboratory. The aim of this study is to…”
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Systemic microvascular dysfunction in microvascular and vasospastic angina
Published in European heart journal (07-12-2018)“…Coronary microvascular dysfunction and/or vasospasm are potential causes of ischaemia in patients with no obstructive coronary artery disease (INOCA). We…”
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Myocardial and Systemic Inflammation in Acute Stress-Induced (Takotsubo) Cardiomyopathy
Published in Circulation (New York, N.Y.) (26-03-2019)“…BACKGROUND:Acute stress-induced (takotsubo) cardiomyopathy can result in a heart failure phenotype with a prognosis comparable with that of myocardial…”
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Validation of a novel non-hyperaemic index of coronary artery stenosis severity: the Resting Full-cycle Ratio (VALIDATE RFR) study
Published in EuroIntervention (01-09-2018)“…Randomised controlled trials have reported instantaneous wave-free ratio (iFR) to be non-inferior to fractional flow reserve (FFR) for major adverse…”
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VERIFY (VERification of Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis Severity in EverydaY Practice)
Published in Journal of the American College of Cardiology (02-04-2013)“…Objectives This study sought to compare fractional flow reserve (FFR) with the instantaneous wave-free ratio (iFR) in patients with coronary artery disease and…”
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