Search Results - "Oldfield, Mark F."

Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry by Grace, Philip B, Taylor, James I, Botting, Nigel P, Fryatt, Tara, Oldfield, Mark F, Bingham, Sheila A

“…Phytoestrogens (isoflavones and lignans) are of increasing interest due to their potential to prevent certain types of complex diseases. However,…”
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Synthesis of [4- 13C]-Isoflavonoid Phytoestrogens by Whalley, Jacqueline L, Oldfield, Mark F, Botting, Nigel P

“…Efficient syntheses are described for 13C-labelled derivatives of the isoflavonoid phytoestrogens, genistein, biochanin A, daidzein and formononetin, for use…”
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A convergent stereocontrolled synthesis of [3-14C]solanesol by Roe, Stephen J., Oldfield, Mark F., Geach, Neil, Baxter, Andrew

“…In this communication, we report the synthesis of ~5 mCi of [3‐14C]solanesol (1) prepared from ethyl [3‐14C]acetoacetate and (all‐E)‐octaprenyl bromide (2) in…”
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Measurement of intact sulfate and glucuronide phytoestrogen conjugates in human urine using isotope dilution liquid chromatography-tandem mass spectrometry with [formula omitted]isoflavone internal standards by Clarke, Don B, Lloyd, Antony S, Botting, Nigel P, Oldfield, Mark F, Needs, Paul W, Wiseman, Helen

“…A method has been developed for the analysis of phytoestrogens and their conjugates in human urine using liquid chromatography electrospray ionization tandem…”
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Quantification of isoflavones and lignans in serum using isotope dilution liquid chromatography/tandem mass spectrometry by Grace, Philip B., Taylor, James I., Botting, Nigel P., Fryatt, Tara, Oldfield, Mark F., Al-Maharik, Nawaf, Bingham, Sheila A.

“…Phytoestrogens (isoflavones and lignans) are receiving increasing attention due to a potential protective effect against a number of complex diseases. However,…”
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Synthesis of [3,4,8- 13C 3]daidzein by Oldfield, Mark F, Chen, Lirong, Botting, Nigel P

“…The biological effects of the soy isoflavones have attracted considerable interest in recent years leading to numerous studies on dietary intake and…”
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The synthesis of [3,4,1′-13C3]genistein by Oldfield, Mark F., Chen, Lirong, Botting, Nigel P.

“…A facile synthesis is described for [3,4,1′‐13C3]genistein for use as an internal standard in isoflavone analysis by mass spectrometric methods. Ethyl…”
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An international quality assurance scheme for the quantitation of daidzein and genistein in food, urine and plasma by Key, Pauline E., Finglas, Paul M., Coldham, Nick, Botting, Nigel, Oldfield, Mark F., Wood, Roger

“…This quality assurance (proficiency testing) scheme was commissioned to enable the Food Standards Agency (FSA) to determine the quality of analytical results…”
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Abstracts of the 21st International Isotope Society (UK group) symposium: synthesis and applications of labelled compounds 2012 by Årstad, Erik, Badar, Adam, Baxter, Andrew, Bower, John F., Cable, Karl M., Carroll, Michael A., Chan, Melanie Y. T., Charlton, Michael, Christlieb, Martin, Cornelissen, Bart, Cox, Liam R., Davis, Ben, Dilworth, Jonathan R., El-Emir, Ethaar, Ellames, George J., Galante, Eva, Geach, Neil, Gee, Antony D., Gouverneur, Véronique, Gregson, Thomas J., Hendry, David, Hueting, Rebekka, Hussien, Kamila, Ilyas, Tenzeela, Jenkins, Daniel D., Kersemans, Veerle, Knagg, Eric, Koepp, Matthias, Kohler, Andrew D., Krauser, Joel A., Launay, Guillaume G., Lockley, William J. S., Lythgoe, Mark F., Manthorpe, Daniel P., McEwen, Andrew, Muschel, Ruth J., Oldfield, Mark F., Passchier, Jan, Pedley, R. Barbara, Rajkumar, Vineeth, Reed, Christopher D., Robson, Mathew, Roe, Stephen J., Ryan, Jim J., Sander, Kerstin, Shipley, Nick, Smart, Sean C., Smith, Neil, Spurr, Daniel W., Taylor, Keith R., Tredwell, Matthew, Whitehead, David M., Woolley, Geoffrey, Yan, Ran

“…Meeting Summary The 21st annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College,…”
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Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women by SETCHELL, Kenneth D. R, FAUGHNAN, Marian S, CASSIDY, Aedin, AVADES, Tony, ZIMMER-NECHEMIAS, Linda, BROWN, Nadine M, WOLFE, Brian E, BRASHEAR, Wayne T, DESAI, Panjak, OLDFIELD, Mark F, BOTTING, Nigel P

“…Despite significant interest in the risks and benefits of phytoestrogens to human health, few data exist on their pharmacokinetics in humans. We investigated…”
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Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women123 by Setchell, Kenneth DR, Faughnan, Marian S, Avades, Tony, Zimmer-Nechemias, Linda, Brown, Nadine M, Wolfe, Brian E, Brashear, Wayne T, Desai, Panjak, Oldfield, Mark F, Botting, Nigel P, Cassidy, Aedin

“…Despite significant interest in the risks and benefits of phytoestrogens to human health, few data exist on their pharmacokinetics in humans. We investigated…”
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Synthesis of [1-13C] and [1-15N] labelled DL-homophenylalanine via a key Neber rearrangement by Oldfield, Mark F., Botting, Nigel P.

“…A synthetic route involving a key Neber rearrangement is described for the preparation of both [1‐13C] and [1‐15N] DL‐homophenylalanine…”
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Biochemical characterisation of an aldoxime-forming flavoprotein involved in 2-phenylethylglucosinolate biosynthesis in Brassica species by Oldfield, Mark F., Bennett, Richard N., Kiddle, Guy, Wallsgrove, Roger M., Botting, Nigel P.

“…L-Homophenylalanine (L-HPhe) is the precursor of 2-phenylethylglucosinolate, a secondary metabolite present in some Brassica and related species. A key step in…”
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