Search Results - "Oldeschulte, James"

Genetic engineering a large animal model of human hypophosphatasia in sheep by Williams, Diarra K., Pinzón, Carlos, Huggins, Shannon, Pryor, Jane H., Falck, Alyssa, Herman, Forrest, Oldeschulte, James, Chavez, Michael B., Foster, Brian L., White, Sarah H., Westhusin, Mark E., Suva, Larry J., Long, Charles R., Gaddy, Dana

“…The availability of tools to accurately replicate the clinical phenotype of rare human diseases is a key step toward improved understanding of disease…”
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Modeling Hypophosphatasia in Ovies aries (sheep) using CRISPR/Cas9: Development of large animal models that phenocopy rare human bone diseases by Williams, Diarra, Pinzon, Carlos, Oldeschulte, James, Huggins, Shannon, Gaddy, Dana, Suva, Larry

“…Hypophosphatasia is a rare inherited disorder that affects the development of bones and teeth caused by mutations in the tissue‐nonspecific alkaline…”
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Genetically Engineering a Sheep Model of Hypophosphatasia by Williams, Diarra Kevin, Pinzon, Carlos A., Huggins, Shannon, Pryor, Jane H., Georges, Hanah M., Hermann, Forrest, Oldeschulte, James, Westhusin, Mark E., Long, Charles R., Gaddy, Dana, Suva, Larry J.

“…Hypophosphatasia (HPP) is a rare inherited disorder that affects the development of bones and teeth. The disease is caused by mutations in the…”
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Abstracts from the First Scientific Meeting of the Soft Bones Foundation by Graham, R, Russell, G, Whyte, Michael P, Coburn, Stephen, Ericson, Karen, Mahuren, Dennis, Townsend, Douglas, Millán, José Luis, Suva, Larry, Williams, Diarra K, Pinzón, Carlos, Huggins, Shannon, Pryor, Jane H, Falck, Alyssa, Herman, Forrest, Oldeschulte, James, Foster, Brian L, Westhusin, Mark E, Long, Charles R, Gaddy, Dana, Krakow, Deborah, Wenkert, Deborah, Mumm, Steven, Crine, Philippe, Simmons, Jill, Bishop, Nick, Saraff, Vrinda, Ozono, Keiichi, Kitaoka, Taichi, Kubota, Takuo, Gottesman, Gary S, Griffin, Donna, Morrison, Erica, Wallenberg, Jennifer, Bijanki, Vinieth N., Zhang, Fan, Seefried, Lothar, Tebben, Peter, Singer, Frederick R, Kishnani, Priya S, Camacho, Pauline M, Rallo, Mark S, Wright, Tim, Foster, Brian, Chavez, MB, Kramer, K, Kolli, TN, Tan, MH, Narisawa, S, Gaddy, D, Suva, LJ, Whyte, MP, Millan, JL, Rosen, Clifford, Orriss, Isabel R, Mortensen, Luke J

“…Michael Whyte, MD, described the discovery in 1923 of alkaline phosphatase (ALP), the first report in 1948 of HPP, and the many important lessons from…”
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