Search Results - "Oldershaw, A"

Cell sources for the regeneration of articular cartilage: the past, the horizon and the future by Oldershaw, Rachel A.

“…Summary Avascular, aneural articular cartilage has a low capacity for self‐repair and as a consequence is highly susceptible to degradative diseases such as…”
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The socio-emotional processing stream in Anorexia Nervosa by Oldershaw, A., Hambrook, D., Stahl, D., Tchanturia, K., Treasure, J., Schmidt, U.

“…Oldershaw, A., Hambrook, D., Stahl, D., Tchanturia, K., Treasure, J., Schmidt, U., 2010. The socio-emotional processing stream in Anorexia Nervosa. Neurosci…”
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Juvenile idiopathic arthritis: from aetiopathogenesis to therapeutic approaches by Zaripova, Lina N, Midgley, Angela, Christmas, Stephen E, Beresford, Michael W, Baildam, Eileen M, Oldershaw, Rachel A

“…Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatological disorder and is classified by subtype according to International League of…”
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Directed differentiation of human embryonic stem cells toward chondrocytes by Baxter, Melissa A, Bates, Nicola, Brison, Daniel R, Oldershaw, Rachel A, Grady, Lisa M, Hardingham, Timothy E, Kimber, Susan J, Soncin, Francesca, Lowe, Emma T

“…Degeneration of articular cartilage in the joints may be amenable to tissue engineering solutions. Oldershaw et al . present an efficient, chemically defined…”
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Mesenchymal Stem Cells in the Pathogenesis and Therapy of Autoimmune and Autoinflammatory Diseases by Zaripova, Lina N, Midgley, Angela, Christmas, Stephen E, Beresford, Michael W, Pain, Clare, Baildam, Eileen M, Oldershaw, Rachel A

“…Mesenchymal stem cells (MSCs) modulate immune responses and maintain self-tolerance. Their trophic activities and regenerative properties make them potential…”
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1H NMR Metabolite Monitoring during the Differentiation of Human Induced Pluripotent Stem Cells Provides New Insights into the Molecular Events That Regulate Embryonic Chondrogenesis by Coope, Ashley, Ghanameh, Zain, Kingston, Olivia, Sheridan, Carl M., Barrett-Jolley, Richard, Phelan, Marie M., Oldershaw, Rachel A.

“…The integration of cell metabolism with signalling pathways, transcription factor networks and epigenetic mediators is critical in coordinating molecular and…”
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Decision making and problem solving in adolescents who deliberately self-harm by Oldershaw, A, Grima, E, Jollant, F, Richards, C, Simic, M, Taylor, L, Schmidt, U

“…Healthy adolescents, and adults who engage in reward-driven, risky behaviours, demonstrate poor decision-making ability. Decision making in deliberate…”
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Cardiac Mesenchymal Stem Cell-like Cells Derived from a Young Patient with Bicuspid Aortic Valve Disease Have a Prematurely Aged Phenotype by Oldershaw, Rachel A, Richardson, Gavin, Carling, Phillippa, Owens, W Andrew, Lundy, David J, Meeson, Annette

“…There is significant interest in the role of stem cells in cardiac regeneration, and yet little is known about how cardiac disease progression affects native…”
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Cartilage, SOX9 and Notch signals in chondrogenesis by Hardingham, Timothy E., Oldershaw, Rachel A., Tew, Simon R.

“…Cartilage repair is an ongoing medical challenge. Tissue engineered solutions to this problem rely on the availability of appropriately differentiated cells in…”
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Notch signaling during chondrogenesis of human bone marrow stem cells by Oldershaw, Rachel A, Hardingham, Tim E

“…Abstract Notch signaling is an important mechanism involved in early development which helps to determine the differentiation and fate of cells destined to…”
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Replacement of the Trabecular Meshwork Cells-A Way Ahead in IOP Control? by Fan, Xiaochen, Bilir, Emine K, Kingston, Olivia A, Oldershaw, Rachel A, Kearns, Victoria R, Willoughby, Colin E, Sheridan, Carl M

“…Glaucoma is one of the leading causes of vision loss worldwide, characterised with irreversible optic nerve damage and progressive vision loss. Primary…”
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The diagnostic accuracy of clinical tests for anterior cruciate ligament tears are comparable but the Lachman test has been previously overestimated: a systematic review and meta-analysis by Sokal, Pawel A., Norris, Richard, Maddox, Thomas W., Oldershaw, Rachel A.

“…Purpose The diagnostic accuracy of clinical tests for anterior cruciate ligament injury has been reported in previous systematic reviews. Numerous studies in…”
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Emotion recognition and emotional theory of mind in chronic fatigue syndrome by Oldershaw, A., Hambrook, D., Rimes, K.A., Tchanturia, K., Treasure, J., Richards, S., Schmidt, U., Chalder, T.

“…Background: Difficulties with social function have been reported in chronic fatigue syndrome (CFS), but underpinning factors are unknown. Emotion recognition,…”
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Inline dynamometry provides reliable measurements of quadriceps strength in healthy and ACL-reconstructed individuals and is a valid substitute for isometric electromechanical dynamometry following ACL reconstruction by Norris, Richard, Morrison, Scot, Price, Alan, Pulford, Sian, Meira, Erik, O'Neill, Seth, Williams, Huw, Maddox, Thomas W., Carter, Paul, Oldershaw, Rachel A.

“…Quadriceps strength testing is recommended to guide rehabilitation and mitigate the risk of second injury following anterior cruciate ligament (ACL)…”
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Derivation of Man-1 and Man-2 research grade human embryonic stem cell lines by Camarasa, Maria V, Kerr, Robbie W, Sneddon, Sharon F, Bates, Nicola, Shaw, Lisa, Oldershaw, Rachel A, Small, Fiona, Baxter, Melissa A, Mckay, Tristan R, Brison, Daniel R, Kimber, Susan J

“…We report here the derivation of two new human embryonic stem cell lines, Man-1 and Man-2, and their full characterization as novel pluripotent stem cell…”
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Notch Signaling Through Jagged‐1 Is Necessary to Initiate Chondrogenesis in Human Bone Marrow Stromal Cells but Must Be Switched off to Complete Chondrogenesis by Oldershaw, Rachel A., Tew, Simon R., Russell, Amanda M., Meade, Kate, Hawkins, Robert, McKay, Tristan R., Brennan, Keith R., Hardingham, Timothy E.

“…We investigated Notch signaling during chondrogenesis in human bone marrow stromal cells (hMSC) in three‐dimensional cell aggregate culture. Expression…”
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Biocompatibility and enhanced osteogenic differentiation of human mesenchymal stem cells in response to surface engineered poly(d,l-lactic-co-glycolic acid) microparticles by Rogers, Catherine M., Deehan, David J., Knuth, Callie A., Rose, Felicity R. A. J., Shakesheff, Kevin M., Oldershaw, Rachel A.

“…Tissue engineering strategies can be applied to enhancing osseous integration of soft tissue grafts during ligament reconstruction. Ligament rupture results in…”
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Emotional theory of mind and emotional awareness in recovered anorexia nervosa patients by Oldershaw, Anna, Hambrook, David, Tchanturia, Kate, Treasure, Janet, Schmidt, Ulrike

“…To examine whether an impaired ability to infer emotion in people with autism spectrum disorder (ASD) and difficulty with emotional theory of mind (eToM) are…”
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Luminal Ca2+ increases the affinity of inositol 1,4,5-trisphosphate for its receptor by OLDERSHAW, K. A, TAYLOR, C. W

“…Luminal Ca2+ has been proposed to regulate the sensitivity of intracellular Ca2+ stores to InsP3 and perhaps thereby to contribute to the mechanisms…”
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Low Oxygen Tension is Critical for the Culture of Human Mesenchymal Stem Cells with Strong Osteogenic Potential from Haemarthrosis Fluid by Knuth, Callie A., Clark, Marcia E., Meeson, Annette P., Khan, Sameer K., Dowen, Daniel J., Deehan, David J., Oldershaw, Rachel A.

“…Satisfactory osseous tissue integration of the soft tissue graft with bone is the mainstay of healing following surgical reconstruction of the anterior…”
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