Search Results - "Oldenburg, RA"

PATIENTS WITH GENOTYPE-POSITIVE HYPERTROPHIC CARDIOMYOPATHY ARE AT INCREASED RISK OF HEART FAILURE RELATED DEATH by van Velzen, H.G, Vriesendorp, P.A, Oldenburg, R.A, van Slegtenhorst, M.A, Schinkel, A.F.L, Michels, M

“…End diastolic LV diameter (HR 1.1, p=0.001) and pathogenic mutation (HR 2.9, p=0.006) were independent risk factors for all-cause mortality…”
Get full text

Performance of BRCA1/2 mutation prediction models in male breast cancer patients by Moghadasi, S., Grundeken, V., Janssen, L.A.M., Dijkstra, N.H., Rodríguez‐Girondo, M., van Zelst‐Stams, W.A.G., Oosterwijk, J.C., Ausems, M.G.E.M., Oldenburg, R.A., Adank, M.A., Blom, E.W., Ruijs, M.W.G., van Os, T.A.M., van Deurzen, C.H.M., Martens, J.W.M., Schroder, C.P., Wijnen, J.T., Vreeswijk, M.P.G., van Asperen, C.J.

“…To establish whether existing mutation prediction models can identify which male breast cancer (MBC) patients should be offered BRCA1 and BRCA2 diagnostic DNA…”
Get full text

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations by VAN BEERS, Erik H, VAN WELSEM, Tibor, NEDERLOF, Petra M, WESSELS, Lodewyk F. A, YUNLEI LI, OLDENBURG, Rogier A, DEVILEE, Peter, CORNEHSSE, Cees J, VERHOEF, Senno, HOGERVORST, Frans B. L, VAN'T VEER, Laura J

“…BRCA1 or BRCA2 germline mutations cause approximately 30% of breast cancers within high-risk families. This represents 5% of total breast cancer incidence…”
Get full text

The CHEK21100delC variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families by OLDENBURG, Rogier A, KROEZE-JANSEMA, Karin, MEIJERS-HEIJBOER, Hanne, DE BOCK, Truuske H, CORNELISSE, Cees J, DEVILEE, Peter, KRAAN, Jaennelle, MORREAU, Hans, KLIJN, Jan G. M, HOOGERBRUGGE, Nicoline, LIGTENBERG, Marjolein J. L, VAN ASPEREN, Christi J, VASEN, Hans F. A, MEIJERS, Carel

“…The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been reported to be associated with familial breast cancer in…”
Get full text

A genome-wide association scan on estrogen receptor-negative breast cancer by Li, Jingmei, Humphreys, Keith, Darabi, Hatef, Rosin, Gustaf, Hannelius, Ulf, Heikkinen, Tuomas, Aittomäki, Kristiina, Blomqvist, Carl, Pharoah, Paul Dp, Dunning, Alison M, Ahmed, Shahana, Hooning, Maartje J, Hollestelle, Antoinette, Oldenburg, Rogier A, Alfredsson, Lars, Palotie, Aarno, Peltonen-Palotie, Leena, Irwanto, Astrid, Low, Hui Qi, Teoh, Garrett Hk, Thalamuthu, Anbupalam, Kere, Juha, D'Amato, Mauro, Easton, Douglas F, Nevanlinna, Heli, Liu, Jianjun, Czene, Kamila, Hall, Per

“…Breast cancer is a heterogeneous disease and may be characterized on the basis of whether estrogen receptors (ER) are expressed in the tumour cells. ER status…”
Get full text

Characterization of Familial Non-BRCA1/2 Breast Tumors by Loss of Heterozygosity and Immunophenotyping by OLDENBURG, Rogier A, KROEZE-JANSEMA, Karin, MORREAU, Hans, CORNELISSE, Cees J, DEVILEE, Peter, MEIJERS-HEIJBOER, Hanne, VAN ASPEREN, Cristi J, HOOGERBRUGGE, Nicoline, VAN LEEUWEN, Inge, VASEN, Hans F. A, CLETON-JANSEN, Anne-Marie, KRAAN, Jaennelle, HOUWING-DUISTERMAAT, Jeanine J

“…Purpose: Since the identification of BRCA1 and BRCA2 , there has been no major breast cancer susceptibility gene discovered by linkage analysis in breast…”
Get full text

Are ATM mutations 7271T→G and IVS10-6T→G really high-risk breast cancer-susceptibility alleles? by SZABO, Csilla I, SCHUTTE, Mieke, FLOORE, Arno N, KRAAN, Jaennelle, KLIJN, Jan G. M, VAN DEN OUWELAND, Ans M. W, WAGNER, Teresa M. U, DEVILEE, Peter, SIMARD, Jacques, VAN'T VEER, Laura J, GOLDGAR, David E, MEIJERS-HEIJBOER, Hanne, BROEKS, Annegien, HOUWING-DUISTERMAAT, Jeanine J, THORSTENSON, Yvonne R, DUROCHER, Francine, OLDENBURG, Rogier A, WASIELEWSKI, Marijke, ODEFREY, Fabrice, THOMPSON, Deborah

“…Two mutations of the ATM gene were recently suggested to confer breast cancer risks similar to mutations of BRCA1 or BRCA2. Here, we set out to confirm these…”
Get full text

Genome-wide scanning for linkage in 56 Dutch breast cancer families selected for a minimal probability of being due to BRCA1 or BRCA2 by Oldenburg, RA, Kroeze-Jansema, K, Houwing, JJ, Kraan, J, Klijn, JG, Hoogerbrugge, N, Ligtenberg, MJ, van Asperen, CJ, Vasen, HF, Meijers-Heijboer, H, Cornelisse, CJ, Devilee, P

Get full text

Extending the p16-Leiden tumour spectrum by respiratory tract tumours by Oldenburg, R A, de Vos tot Nederveen Cappel, W H, van Puijenbroek, M, van den Ouweland, A, Bakker, E, Griffioen, G, Devilee, P, Cornelisse, C J, Meijers-Heijboer, H, Vasen, H F A, Morreau, H

Get full text