Search Results - "Oldebeken, Scott"

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity by Ramkhelawon, Bhama, Hennessy, Elizabeth J, Ménager, Mickaël, Ray, Tathagat Dutta, Sheedy, Frederick J, Hutchison, Susan, Wanschel, Amarylis, Oldebeken, Scott, Geoffrion, Michele, Spiro, Westley, Miller, George, McPherson, Ruth, Rayner, Katey J, Moore, Kathryn J

“…Obesity is marked by a state of low-grade inflammation, including the accumulation of macrophages in the adipose tissue, which results in insulin resistance…”
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Glutathione Peroxidase-1 Deficiency Augments Proinflammatory Cytokine-induced Redox Signaling and Human Endothelial Cell Activation by Lubos, Edith, Kelly, Neil J., Oldebeken, Scott R., Leopold, Jane A., Zhang, Ying-Yi, Loscalzo, Joseph, Handy, Diane E.

“…Glutathione peroxidase-1 (GPx-1) is a crucial antioxidant enzyme, the deficiency of which promotes atherogenesis. Accordingly, we examined the mechanisms by…”
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LDL Receptor Pathway Regulation by miR-224 and miR-520d by Salerno, Alessandro G., van Solingen, Coen, Scotti, Elena, Wanschel, Amarylis C. B. A., Afonso, Milessa S., Oldebeken, Scott R., Spiro, Westley, Tontonoz, Peter, Rayner, Katey J., Moore, Kathryn J.

“…MicroRNAs (miRNA) have emerged as important post-transcriptional regulators of metabolic pathways that contribute to cellular and systemic lipoprotein…”
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High-Throughput Screening Identifies MicroRNAs Regulating Human PCSK9 and Hepatic Low-Density Lipoprotein Receptor Expression by van Solingen, Coen, Oldebeken, Scott R., Salerno, Alessandro G., Wanschel, Amarylis C. B. A., Moore, Kathryn J.

“…Investigations into the regulatory mechanisms controlling cholesterol homeostasis have proven fruitful in identifying low-density lipoprotein (LDL)-lowering…”
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Tumor necrosis factor-α-mediated suppression of dual-specificity phosphatase 4: crosstalk between NFκB and MAPK regulates endothelial cell survival by Kao, Derrick D., Oldebeken, Scott R., Rai, Anjali, Lubos, Edith, Leopold, Jane A., Loscalzo, Joseph, Handy, Diane E.

“…We investigated the effects of tumor necrosis factor-α (TNF-α) exposure on mitogen-activated protein kinase signaling in human microvascular endothelial cells…”
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Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism by Ouimet, Mireille, Koster, Stefan, Sakowski, Erik, Ramkhelawon, Bhama, van Solingen, Coen, Oldebeken, Scott, Karunakaran, Denuja, Portal-Celhay, Cynthia, Sheedy, Frederick J, Ray, Tathagat Dutta, Cecchini, Katharine, Zamore, Philip D, Rayner, Katey J, Marcel, Yves L, Philips, Jennifer A, Moore, Kathryn J

“…Mycobacterium tuberculosis (Mtb) survives in macrophages by evading delivery to the lysosome and promoting the accumulation of lipid bodies, which serve as a…”
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Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: mechanism for macrophage retention and survival by Ramkhelawon, Bhama, Yang, Yuan, van Gils, Janine M, Hewing, Bernd, Rayner, Katey J, Parathath, Sajesh, Guo, Liang, Oldebeken, Scott, Feig, Jessica L, Fisher, Edward A, Moore, Kathryn J

“…Hypoxia is intimately linked to atherosclerosis and has become recognized as a primary impetus of inflammation. We recently demonstrated that the neuroimmune…”
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Abstract 63: Post-transcriptional Control of the LDLR Pathway by Cholesterol-responsive microRNAs by Salerno, Alessandro G, Rayner, Katey J, Wanschel, Amarylis C, Oldebeken, Scott R, Scotti, Elena, Tontonoz, Peter, Moore, Kathryn J

“…Abstract only Despite the success of statins to reduce levels of LDL-cholesterol (LDL-C), cardiovascular disease remains the leading cause of mortality in…”
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Tumor necrosis factor-[alpha]-mediated suppression of dual-specificity phosphatase 4: crosstalk between NF[kappa]B and MAPK regulates endothelial cell survival by Kao, Derrick D, Oldebeken, Scott R, Rai, Anjali, Lubos, Edith, Leopold, Jane A, Loscalzo, Joseph, Handy, Diane E

“…We investigated the effects of tumor necrosis factor-[alpha] (TNF-[alpha]) exposure on mitogen-activated protein kinase signaling in human microvascular…”
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Abstract 610: Netrin-1 Promotes Macrophage Accumulation and Insulin Resistance in Obesity by Ramkhelawon, Bhama, Hennessy, Elizabeth J, Menager, Mickael, Ray, Tathagat D, Sheedy, Frederick J, Babunovic, Susan, Miller, George, Oldebeken, Scott, Geoffrion, Michele, McPherson, Ruth, Rayner, Katey J, Moore, Kathryn J

“…Abstract only Obesity and its co-morbidities, type 2 diabetes and cardiovascular disease, continue to increase and are a major threat to global health. Studies…”
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Netrin-1 promotes adipose tissue macrophage accumulation and insulin resistance in obesity by Ramkhelawon, Bhama, Hennessy, Elizabeth J, Ménager, Mickaël, Ray, Tathagat Dutta, Sheedy, Frederick J, Hutchison, Susan, Wanschel, Amarylis, Oldebeken, Scott, Geoffrion, Michele, Spiro, Westley, Miller, George, McPherson, Ruth, Rayner, Katey J, Moore, Kathryn J

“…During obesity, macrophage accumulation in adipose tissue propagates the chronic inflammation and insulin resistance associated with type 2 diabetes. The…”
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A Gross Anatomical and Histopathological Investigation of Cause of Death in a Cadaver in an Undergraduate Anatomy Lab by Green, Erin Kelly, Jordan, Clayton W., Oldebeken, Scott R., Paudyal, Sharad C., Roehrs, Jennifer E., Potterfield, April

“…Abstract only An undergraduate gross anatomy dissection was performed at Westminster College as part of a human anatomy class, with one objective being to…”
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