Search Results - "Olde Damink, S. W. M."
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1
Bile acids drive the newborn’s gut microbiota maturation
Published in Nature communications (23-07-2020)“…Following birth, the neonatal intestine is exposed to maternal and environmental bacteria that successively form a dense and highly dynamic intestinal…”
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2
Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome
Published in PloS one (18-03-2016)“…Pancreatic cancer has a 5-year survival rate of less than 4%. Despite advances in diagnostic technology, pancreatic cancer continues to be diagnosed at a late…”
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3
Study protocol on the role of intestinal microbiota in colorectal cancer treatment: a pathway to personalized medicine 2.0
Published in International journal of colorectal disease (01-07-2017)“…Purpose Investigate in patients with metastatic and/or irresectable colorectal cancer treated with systemic treatment with capecitabine or TAS-102 whether:…”
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4
Patient‐derived organoid models help define personalized management of gastrointestinal cancer
Published in British journal of surgery (01-01-2018)“…Background The prognosis of patients with different gastrointestinal cancers varies widely. Despite advances in treatment strategies, such as extensive…”
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Systematic review of the influence of chemotherapy‐associated liver injury on outcome after partial hepatectomy for colorectal liver metastases
Published in British journal of surgery (01-07-2017)“…Background The impact of chemotherapy‐associated liver injury (CALI) on postoperative outcome in patients undergoing partial hepatectomy for colorectal liver…”
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Effects of Postoperative Morbidity on Long-Term Outcome Following Surgery for Colorectal Liver Metastases
Published in World journal of surgery (01-02-2015)“…Background The impact of postoperative complications on long-term outcomes after surgery for colorectal liver metastases (CRLM) remains controversial. During…”
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Review article: surgical, neo‐adjuvant and adjuvant management strategies in biliary tract cancer
Published in Alimentary pharmacology & therapeutics (01-11-2011)“…Aliment Pharmacol Ther 2011; 34: 1063–1078 Summary Background The majority of patients with cholangiocarcinoma present with advanced, irresectable tumours…”
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Feasibility of randomized controlled trials in liver surgery using surgery-related mortality or morbidity as endpoint
Published in British journal of surgery (01-09-2009)“…Background: There is a shortage of randomized controlled trials (RCTs) on which to base guidelines in liver surgery. The feasibility of conducting an…”
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9
Role of ammonia and inflammation in minimal hepatic encephalopathy
Published in Metabolic brain disease (01-03-2007)“…Minimal hepatic encephalopathy (MHE) is common in cirrhosis but its pathophysiologic basis remains undefined. We evaluated whether the presence of MHE was…”
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Review article: pancreatic renin–angiotensin systems in health and disease
Published in Alimentary pharmacology & therapeutics (01-10-2011)“…Aliment Pharmacol Ther 2011; 34: 840–852 Summary Background In addition to the circulating (endocrine) renin–angiotensin system (RAS), local renin–angiotensin…”
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11
Development of a composite endpoint for randomized controlled trials in liver surgery
Published in British journal of surgery (01-08-2011)“…Background: The feasibility of randomized controlled trials (RCTs) in liver surgery using a single‐component clinical endpoint is low as such endpoints require…”
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12
Overnight glucose infusion suppresses renal ammoniagenesis and reduces hyperammonaemia induced by a simulated bleed in cirrhotic patients
Published in Alimentary pharmacology & therapeutics (01-04-2012)“…Summary Background A simulated upper gastrointestinal (UGI) bleed in cirrhotic patients has been shown to induce hyperammonaemia. The kidney was the site of…”
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13
Alternatives to antibiotics for prevention of surgical infection
Published in British journal of surgery (01-01-2017)“…Background Surgical‐site infection (SSI) is still the second most common healthcare‐associated infection, after respiratory tract infection. SSIs are…”
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14
Is sarcopenia a risk factor for reduced diaphragm function following hepatic resection? A study protocol for a prospective observational study
Published in BMJ open (16-11-2021)“…IntroductionSarcopenia is associated with reduced pulmonary function in healthy adults, as well as with increased risk of pneumonia following abdominal…”
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Ammonia and hepatic encephalopathy : The more things change, the more they remain the same
Published in Metabolic brain disease (01-09-2005)“…Ammonia is thought to be central in the pathogenesis of hepatic encephalopathy and has been of importance to generations dating back to the early Egyptians…”
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16
Glutathione S-transferase M1-null genotype as risk factor for SOS in oxaliplatin-treated patients with metastatic colorectal cancer
Published in British journal of cancer (19-02-2013)“…Background: Oxaliplatin is used as a neo-adjuvant therapy in hepatic colorectal carcinoma metastasis. This treatment has significant side effects, as…”
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17
Acute endotoxemia following transjugular intrahepatic stent-shunt insertion is associated with systemic and cerebral vasodilatation with increased whole body nitric oxide production in critically ill cirrhotic patients
Published in Journal of hepatology (01-02-2011)“…Background & Aims Transjugular intrahepatic stent-shunt (TIPSS) insertion, in patients with uncontrolled gastro-intestinal bleeding, often results in worsening…”
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Review article: hyperammonaemic and catabolic consequences of upper gastrointestinal bleeding in cirrhosis
Published in Alimentary pharmacology & therapeutics (15-04-2009)“…Summary Background Upper gastrointestinal (UGI) bleeding in patients with cirrhosis of the liver induces hyperammonaemia and leads to a catabolic cascade that…”
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Health-related quality of life in patients treated for enterocutaneous fistula
Published in British journal of surgery (01-10-2008)“…Background: Patients with enterocutaneous fistulas undergo long intensive treatment. The aim of this study was to investigate the long‐term health‐related…”
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The influence of sarcopenia on survival and surgical complications in ovarian cancer patients undergoing primary debulking surgery
Published in European journal of surgical oncology (01-04-2017)“…Abstract Background Sarcopenia, severe skeletal muscle loss, has been identified as a prognostic factor in various malignancies. This study aims to investigate…”
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