Search Results - "Oldach, Maureen"
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Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C
Published in Scientific reports (26-06-2023)“…We sought to establish a large animal model of inherited hypertrophic cardiomyopathy (HCM) with sufficient disease severity and early penetrance for…”
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Taurine deficiency and dilated cardiomyopathy in golden retrievers fed commercial diets
Published in PloS one (13-12-2018)“…Golden retrievers are over-represented in cases of taurine-deficient dilated cardiomyopathy and recently a surge in cases has prompted further investigation…”
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Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy
Published in Scientific reports (02-01-2023)“…Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiac disease in humans and cats and lacks efficacious pharmacologic interventions in the…”
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A genetic polymorphism in P2RY1 impacts response to clopidogrel in cats with hypertrophic cardiomyopathy
Published in Scientific reports (15-06-2021)“…Clopidogrel is converted to its active metabolite by cytochrome P450 isoenzymes and irreversibly inhibits platelet activation by antagonizing the…”
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Echocardiographic evaluation of velocity ratio, velocity time integral ratio, and pulmonary valve area in dogs with pulmonary valve stenosis
Published in Journal of veterinary internal medicine (01-09-2018)“…Background Velocity ratio, velocity time integral (VTI) ratio, and pulmonary valve area indexed to body surface area (iPVA) are methods of assessment of…”
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Pharmacokinetics of a single dose of Aficamten (CK‐274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model
Published in Journal of veterinary pharmacology and therapeutics (01-01-2023)“…Hypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats and lacks efficacious preclinical pharmacologic intervention, prompting…”
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Acute pharmacodynamic effects of pimobendan in client-owned cats with subclinical hypertrophic cardiomyopathy
Published in BMC veterinary research (23-02-2021)“…Prior studies have suggested that pimobendan is associated with several positive effects in cats, including improved survival in cats with congestive heart…”
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Aberrant migration and surgical removal of a heartworm (Dirofilaria immitis) from the femoral artery of a cat
Published in Journal of veterinary internal medicine (01-03-2018)“…A cat was evaluated for an acute‐onset of right pelvic limb paresis. Thoracic radiographs revealed normal cardiac size and tortuous pulmonary arteries…”
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Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias
Published in Journal of veterinary internal medicine (01-07-2018)“…Background Sotalol is a commonly used antiarrhythmic drug that may alter ventricular function. Objective To determine the effect of sotalol on…”
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Cardiac Effects of a Single Dose of Pimobendan in Cats With Hypertrophic Cardiomyopathy; A Randomized, Placebo-Controlled, Crossover Study
Published in Frontiers in veterinary science (04-02-2019)“…Pimobendan has been shown to impart a significant survival benefit in cardiomyopathic cats who receive it as part of heart failure therapy. However, use of…”
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High-pressure balloon valvuloplasty for severe pulmonary valve stenosis: a prospective observational pilot study in 25 dogs
Published in Journal of veterinary cardiology (01-04-2018)“…We aimed to evaluate safety and efficacy of high-pressure balloon valvuloplasty (HPBVP) for treatment of canine severe pulmonary valve stenosis (PS). A…”
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Correction: Taurine deficiency and dilated cardiomyopathy in golden retrievers fed commercial diets
Published in PloS one (2018)“…[This corrects the article DOI: 10.1371/journal.pone.0209112.]…”
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Synergistic inhibitory effects of clopidogrel and rivaroxaban on platelet function and platelet‐dependent thrombin generation in cats
Published in Journal of veterinary internal medicine (01-07-2023)“…Background Dual antithrombotic treatment (DAT) with clopidogrel and rivaroxaban sometimes is prescribed to cats with hypertrophic cardiomyopathy at risk of…”
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Abstract 14254: Pharmacodynamic Effects of a Single Dose of CK-3773274 in Cats With Hypertrophic Cardiomyopathy
Published in Circulation (New York, N.Y.) (17-11-2020)“…IntroductionHypertrophic cardiomyopathy (HCM) is characterized by left ventricular (LV) hypertrophy in the absence of known causes. HCM can be due to genetic…”
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Closure of a patent ductus arteriosus in a 2-week-old llama cria using an Amplatz canine duct occluder
Published in Canadian veterinary journal (01-07-2022)“…A two-week-old female llama cria was brought to the UC Davis Large Animal Hospital for evaluation of a cardiac murmur and suspected syncopal episodes. A grade…”
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A genetic polymorphism in P2RY 1 impacts response to clopidogrel in cats with hypertrophic cardiomyopathy
Published in Scientific reports (01-06-2021)“…Abstract Clopidogrel is converted to its active metabolite by cytochrome P450 isoenzymes and irreversibly inhibits platelet activation by antagonizing the…”
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