Search Results - "Olaru, Florina"

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy by Luo, Wentian, Olaru, Florina, Miner, Jeffrey H, Beck, Jr, Laurence H, van der Vlag, Johan, Thurman, Joshua M, Borza, Dorin-Bogdan

“…Membranous nephropathy is an immune kidney disease caused by IgG antibodies that form glomerular subepithelial immune complexes. Proteinuria is mediated by…”
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Chemokine expression by human keratinocyte cell lines after activation of Toll-like receptors by Olaru, Florina, Jensen, Liselotte E.

“…Please cite this paper as: Chemokine expression by human keratinocyte cell lines after activation of Toll‐like receptors. Experimental Dermatology 2010; 19:…”
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Controlling the pro-inflammatory function of 6-sulfo LacNAc (slan) dendritic cells with dimethylfumarate by Oehrl, Stephanie, Olaru, Florina, Kunze, Anja, Maas, Michael, Pezer, Silvia, Schmitz, Marc, Schäkel, Knut

“…•DMF inhibits the CX3CR1 and C5a directed migratory capacity of slanDCs.•DMF inhibits the phenotypic maturation of slanDCs, as judged by a reduced CD80, CD86,…”
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Intracapillary immune complexes recruit and activate slan-expressing CD16+ monocytes in human lupus nephritis by Olaru, Florina, Döbel, Thomas, Lonsdorf, Anke S., Oehrl, Stephanie, Maas, Michael, Enk, Alexander H., Schmitz, Marc, Gröne, Elisabeth F., Gröne, Hermann-J., Schäkel, Knut

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Staphylococcus aureus Stimulates Neutrophil Targeting Chemokine Expression in Keratinocytes through an Autocrine IL-1α Signaling Loop by Olaru, Florina, Jensen, Liselotte E.

“…Staphylococcus aureus is a significant human pathogen that can colonize the skin. Neutrophils are well known to be involved in clearance of the bacterium. This…”
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Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease by Shen, Cong-Rong, Jia, Xiao-Yu, Luo, Wentian, Olaru, Florina, Cui, Zhao, Zhao, Ming-Hui, Borza, Dorin-Bogdan

“…Antiglomerular basement membrane (anti-GBM) disease is characterized by GN and often pulmonary hemorrhage, mediated by autoantibodies that typically recognize…”
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Staphylococcus aureus Stimulates Neutrophil Targeting Chemokine Expression in Keratinocytes through an Autocrine IL-1[alpha] Signaling Loop by Olaru, Florina, Jensen, Liselotte E

“…Staphylococcus aureus is a significant human pathogen that can colonize the skin. Neutrophils are well known to be involved in clearance of the bacterium. This…”
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Neonatal Fc receptor deficiency protects from tissue injury in experimental epidermolysis bullosa acquisita by Sesarman, Alina, Sitaru, Ana Gabriela, Olaru, Florina, Zillikens, Detlef, Sitaru, Cassian

“…Epidermolysis bullosa acquisita (EBA) is an autoimmune blistering disease caused by autoantibodies against type VII collagen. The neonatal Fc receptor (FcRn)…”
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Neonatal Fc Receptor Promotes Immune Complex-Mediated Glomerular Disease by OLARU, Florina, WENTIAN LUO, HANI SULEIMAN, ST. JOHN, Patricia L, GE, Linna, MEZO, Adam R, SHAW, Andrey S, ABRAHAMSON, Dale R, MINER, Jeffrey H, BORZA, Dorin-Bogdan

“…The neonatal Fc receptor (FcRn) is a major regulator of IgG and albumin homeostasis systemically and in the kidneys. We investigated the role of FcRn in the…”
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Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers by Olaru, Florina, Wang, Xu-Ping, Luo, Wentian, Ge, Linna, Miner, Jeffrey H, Kleinau, Sandra, Geiger, Xochiquetzal J, Wasiluk, Andrew, Heidet, Laurence, Kitching, A Richard, Borza, Dorin-Bogdan

“…Goodpasture disease is an autoimmune kidney disease mediated by autoantibodies against noncollagenous domain 1 (NC1) monomers of α3(IV) collagen that bind to…”
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Interleukin-1 regulates keratinocyte expression of T cell targeting chemokines through interleukin-1 receptor associated kinase-1 (IRAK1) dependent and independent pathways by Sanmiguel, Julio C., Olaru, Florina, Li, Jieliang, Mohr, Elisabeth, Jensen, Liselotte E.

“…IL-1 is a potent pro-inflammatory cytokine that activates intracellular signaling cascades some of which may involve IL-1 receptor associated kinase-1 (IRAK1)…”
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Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome by Zhang, Jun-Jun, Malekpour, Mahdi, Luo, Wentian, Ge, Linna, Olaru, Florina, Wang, Xu-Ping, Bah, Maimouna, Sado, Yoshikazu, Heidet, Laurence, Kleinau, Sandra, Fogo, Agnes B, Borza, Dorin-Bogdan

“…Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and a significant cause of end-stage renal disease, yet current therapies are…”
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Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome by Zhang, Jun-Jun, Malekpour, Mahdi, Luo, Wentian, Ge, Linna, Olaru, Florina, Wang, Xu-Ping, Bah, Maimouna, Sado, Yoshikazu, Heidet, Laurence, Kleinau, Sandra, Fogo, Agnes B, Borza, Dorin-Bogdan

“…Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and a significant cause of end-stage renal disease, yet current therapies are…”
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Intracapillary immune complexes recruit and activate slan-expressing CD16+ monocytes in human lupus nephritis by Olaru, Florina, Döbel, Thomas, Lonsdorf, Anke S, Oehrl, Stephanie, Maas, Michael, Enk, Alexander H, Schmitz, Marc, Gröne, Elisabeth F, Gröne, Hermann-J, Schäkel, Knut

“…Lupus nephritis is a major cause of morbidity in patients with systemic lupus erythematosus. Among the different types of lupus nephritis, intracapillary…”
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Quaternary Epitopes of α345(IV) Collagen Initiate Alport Post-Transplant Anti-GBM Nephritis by OLARU, Florina, LUO, Wentian, WANG, Xu-Ping, LINNA GE, HERTZ, Jens Michael, KASHTAN, Clifford E, SADO, Yoshikazu, SEGAL, Yoav, HUDSON, Billy G, BORZA, Dorin-Bogdan

“…Alport post-transplant nephritis (APTN) is an aggressive form of anti-glomerular basement membrane disease that targets the allograft in transplanted patients…”
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Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-GBM autoantibodies specific for α345NC1 hexamers by Olaru, Florina, Wang, Xu-Ping, Luo, Wentian, Ge, Linna, Miner, Jeffrey H, Kleinau, Sandra, Geiger, Xochiquetzal J., Wasiluk, Andrew, Heidet, Laurence, Kitching, A. Richard, Borza, Dorin-Bogdan

“…Goodpasture disease is an autoimmune kidney disease mediated by autoAbs against NC1 monomers of α3(IV) collagen that bind to the glomerular basement membrane…”
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Proteolysis Breaks Tolerance toward Intact alpha 345(IV) Collagen, Eliciting Novel Anti-Glomerular Basement Membrane Autoantibodies Specific for alpha 345NC1 Hexamers by Olaru, Florina, Wang, Xu-Ping, Luo, Wentian, Ge, Linna, Miner, Jeffrey H, Kleinau, Sandra, Geiger, Xochiquetzal J, Wasiluk, Andrew, Heidet, Laurence, Kitching, ARichard, Borza, Dorin-Bogdan

“…Goodpasture disease is an autoimmune kidney disease mediated by autoantibodies against noncollagenous domain 1 (NC1) monomers of alpha 3(IV) collagen that bind…”
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Staphylococcus aureus stimulates neutrophil targeting chemokine expression in keratinocytes through an autocrine IL-1alpha signaling loop by Olaru, Florina, Jensen, Liselotte E

“…Staphylococcus aureus is a significant human pathogen that can colonize the skin. Neutrophils are well known to be involved in clearance of the bacterium. This…”
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Generation and characterization of monoclonal antibodies against the intracellular domain of hemidesmosomal type XVII collagen by Olaru, Florina, Mihai, Sidonia, Petrescu, Ioan, Zillikens, Detlef, Sitaru, Cassian

“…Type XVII collagen, also referred to as bullous pemphigoid antigen 2 (BPAG2) or bullous pemphigoid antigen 180 (BP180), is a transmembrane protein of the…”
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