Search Results - "Olalla Saad, Sara Terezinha"

Inflammatory Dendritic Cells Contribute to Regulate the Immune Response in Sickle Cell Disease by Sesti-Costa, Renata, Borges, Marina Dorigatti, Lanaro, Carolina, de Albuquerque, Dulcinéia Martins, Saad, Sara Terezinha Olalla, Costa, Fernando Ferreira

“…Sickle cell disease (SCD), one of the most common hemoglobinopathies worldwide, is characterized by a chronic inflammatory component, with systemic release of…”
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Low SARS‐CoV‐2 seroprevalence in a cohort of Brazilian sickle cell disease patients: Possible effects of emphasis on social isolation for a population initially considered to be at very high risk by Trafane, Luiza Francisco, da Costa, Vitor Antonio, da Silva Santos Duarte, Adriana, Zangirolami, Audrey Basso, Proenca‐Modena, José Luiz, Melo Campos, Paula, Souza Medina, Samuel, Saad, Sara Terezinha Olalla, Addas‐Carvalho, Marcelo, Benites, Bruno Deltreggia

“…Despite being initially considered at higher risk for severe COVID‐19, sickle cell disease (SCD) patients have mostly presented clinical severity similar to…”
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ARHGAP21 modulates FAK activity and impairs glioblastoma cell migration by Bigarella, Carolina Louzão, Borges, Luciene, Costa, Fernando Ferreira, Saad, Sara Terezinha Olalla

“…Glioblastoma multiforme is highly aggressive and is the most common glial tumor type. Although there have been advances in treatment, the average survival…”
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Erythropoiesis‐driven regulation of hepcidin in human red cell disorders is better reflected through concentrations of soluble transferrin receptor rather than growth differentiation factor 15 by Fertrin, Kleber Yotsumoto, Lanaro, Carolina, Franco‐Penteado, Carla Fernanda, Albuquerque, Dulcinéia Martins, Mello, Mariana Rezende Bandeira, Pallis, Flávia Rubia, Bezerra, Marcos André Cavalcanti, Hatzlhofer, Betania Lucena Domingues, Olbina, Gordana, Olalla Saad, Sara Terezinha, Silva Araújo, Aderson, Westerman, Mark, Costa, Fernando Ferreira

“…Growth differentiation factor 15 (GDF‐15) is a bone marrow‐derived cytokine whose ability to suppress iron regulator hepcidin in vitro and increased…”
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Genotype Frequencies at Codon 129 of the Prion Protein Gene in Brazil: Implications in Susceptibility to Variant Creutzfeldt-Jakob Disease Compared to European and Asian Populations by de Paula, Erich Vinicius, Addas-Carvalho, Marcelo, Costa, Devanira Souza Paixao, Saad, Sara Terezinha Olalla, Gilli, Simone Cristina Olenscki

“…A polymorphism at codon 129 of the prion protein gene has been shown to confer genetic susceptibility to prion diseases, and to influence the epidemic course…”
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Acute myocardial infarction in sickle cell disease: a possible complication of hydroxyurea treatment by Fattori, André, de Souza, Robenílson Almeida, Saad, Sara Terezinha Olalla, Costa, Fernando Ferreira

“…We describe a 28-year-old man treated with hydroxyurea for sickle cell anemia, who was admitted to the University Hospital with an acute myocardial infarction…”
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Selection of plasma donors for the production of anti-SARS-CoV-2 immunoglobulin-based therapies: Strategies for quantitative antibody measurements by Benites, Bruno Deltreggia, Costa-Lima, Carolina, Pinto, Fernanda Batista Rosa, da Costa, Vitor Antonio, Duarte, Adriana da Silva Santos, Zangirolami, Audrey Basso, Amaro, Emerson Clayton, Granja, Fabiana, Proenca-Modena, José Luiz, Saad, Sara Terezinha Olalla, Addas-Carvalho, Marcelo

“…Even after two years of the pandemic, a completely effective treatment against SARS-CoV-2 has not yet been established. Considering this fact and the emergence…”
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Expression of Sara2 human gene in erythroid progenitors by Jardim, Denis Leonardo Fontes, da Cunha, Anderson Ferreira, Duarte, Adriana da Silva Santos, dos Santos, Camila Oresco, Saad, Sara Terezinha Olalla, Costa, Fernando Ferreira

“…A human homologue of Sar1, named Sara2, was shown to be preferentially expressed during erythropoiesis in a culture stimulated by EPO. Previous studies, in…”
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Somatic mutations of calreticulin in a Brazilian cohort of patients with myeloproliferative neoplasms by Machado-Neto, João Agostinho, de Melo Campos, Paula, de Albuquerque, Dulcinéia Martins, Costa, Fernando Ferreira, Lorand-Metze, Irene, Olalla Saad, Sara Terezinha, Traina, Fabiola

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Hydroxycarbamide reduces eosinophil adhesion and degranulation in sickle cell anaemia patients by Pallis, Flavia Rubia, Conran, Nicola, Fertrin, Kleber Yotsumoto, Olalla Saad, Sara Terezinha, Costa, Fernando Ferreira, Franco‐Penteado, Carla Fernanda

“…Summary Inflammation, leucocyte and red cell adhesion to the endothelium contribute to the pathogenesis of sickle cell anaemia. Neutrophils appear to be…”
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A Meta-Analysis of Gene Expression Studies Highlights the Role of Innate Immunity in the Pathogenesis of Sickle Cell Disease and Reveals Novel Potential Regulators at the Transcriptomic Level by Hounkpe, Bidossessi Wilfried, Fiusa, Maiara Marx Luz, Colella, Marina Pereira, da Costa, Loredana Nilkenes Gomes, Benatti, Rafaela Oliveira, Saad, Sara Terezinha Olalla, Costa, Fernando Ferreira, Santos, Magnun Nueldo, De Paula, Erich Vinicius

“…Sickle cell disease (SCD) is characterized by chronic inflammation and multisystem tissue damage. Despite the detailed characterization of the inflammatory…”
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Increased Inflammatory Markers and Their Correlations To Clinical Complications In Hemoglobin SC Disease by Colella, Marina Pereira, Vinicius de Paula, Erich, Conran, Nicola, Machado-Neto, Joao, Quaino, Susan K.P., Annichino-Bizzacchi, Joyce M., Costa, Fernando Ferreira, Olalla-Saad, Sara Terezinha, Traina, Fabiola

“…Hemoglobin SC (HbSC) disease is the second most prevalent hemoglobinopathy after sickle cell anemia (SCA – homozygous HbSS). Despite its high prevalence, most…”
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Hydroxyurea Therapy Reduces The Hypercoagulability State In a Sickle Cell Mouse Model by Colella, Marina Pereira, Almeida, Camila Bononi, Conran, Nicola, Pallis, Flavia Rubia, Franco-Penteado, Carla Fernanda, Annichino-Bizzacchi, Joyce Maria, Costa, Fernando Ferreira, Vinicius de Paula, Erich, Olalla-Saad, Sara Terezinha, Traina, Fabiola

“…Several lines of evidence show that sickle cell anemia (SCA) is characterized by a hypercoagulable state. SCA patients present an elevated rate of thrombotic…”
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IFN-β, IFN-γ, and TNF-α decrease erythrophagocytosis by human monocytes independent of SIRP-α or SHP-1 expression by de Almeida, Ana Carolina, Barbosa, Soraya Massaro, de Lourdes Rios Barjas-Castro, Maria, Olalla-Saad, Sara Terezinha, Condino-Neto, Antonio

“…Background: Many cases of autoimmune hemolytic anemia have been reported after viral infection. Phagocyte activation and accompanying erythrophagocytosis are…”
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Clinical, hematological, and molecular characterization of sickle cell anemia pediatric patients from two different cities in Brazil by Lyra, Isa Menezes, Gonçalves, Marilda Souza, Braga, Joseffina A Pellegrinei, Gesteira, Maria de Fátima, Carvalho, Maria Helena, Saad, Sara Terezinha Olalla, Figueiredo, Maria Stella, Costa, Fernando Ferreira

“…This study focused on clinical, hematological, and molecular aspects of sickle cell anemia pediatric patients from two different cites in Brazil. Seventy-one…”
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Discrepancies in p21ras, p53, and Mdm2 Protein Expression Predict Worse Prognosis in Acute Myeloid Leukemia by Schulz, Elizabeth, Lorand-Metze, Irene, Koch, Rainer, Costa, Solange Campelo, Costa, Fernando Ferreira, Saad, Sara Terezinha Olalla

“…Tumor progress is a multistep process in which clones of cells become abnormal by accumulating growth alterations until they are transformed and/or…”
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Transforming-Growth Factor Beta Pathway Components Is Down Regulated in Patients with Chronic Graft Versus Host Disease by Colella, Marcos Paulo, Morini, Beatriz Corey, Lopes, Matheus Rodrigues, Aranha, Francisco J.P, Vigorito, Afonso C, Saad, Sara Terezinha Olalla, Favaro, Patricia

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431 - Transforming-Growth Factor Beta Pathway Components Is Down Regulated in Patients with Chronic Graft Versus Host Disease by Colella, Marcos Paulo, Morini, Beatriz Corey, Lopes, Matheus Rodrigues, Aranha, Francisco J.P., Vigorito, Afonso C., Saad, Sara Terezinha Olalla, Favaro, Patricia

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Clinical, hematological, and molecular characterization of sickle cell anemia pediatric patients from two different cities in Brazil Caracterização clínica, hematológica e molecular de crianças portadoras da anemia falciforme em duas diferentes cidades do Brasil by Isa Menezes Lyra, Marilda Souza Gonçalves, Joseffina A. Pellegrinei Braga, Maria de Fátima Gesteira, Maria Helena Carvalho, Sara Terezinha Olalla Saad, Maria Stella Figueiredo, Fernando Ferreira Costa

“…This study focused on clinical, hematological, and molecular aspects of sickle cell anemia pediatric patients from two different cites in Brazil. Seventy-one…”
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Somatic mutations of calreticulin in a Brazilian cohort of patients with myeloproliferative neoplasms by Machado-Neto, João Agostinho, Campos, Paula de Melo, Albuquerque, Dulcinéia Martins de, Costa, Fernando Ferreira, Lorand-Metze, Irene, Saad, Sara Terezinha Olalla, Traina, Fabiola

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