Search Results - "Olaleye, Tayo"
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Assessing availability, prices, and market share of quality-assured malaria ACT and RDT in the private retail sector in Nigeria and Uganda
Published in Malaria journal (06-02-2024)“…An estimated 50% of suspected malaria cases in sub-Saharan Africa first seek care in the private sector, especially in private medicine retail outlets. Quality…”
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A fluorescence-based assay for N-myristoyltransferase activity
Published in Analytical biochemistry (01-02-2012)“…N-myristoylation is the irreversible attachment of a C 14 fatty acid, myristic acid, to the N-terminal glycine of a protein via formation of an amide bond…”
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3
Peptidomimetic inhibitors of N-myristoyltransferase from human malaria and leishmaniasis parasites
Published in Organic & biomolecular chemistry (07-11-2014)“…N-Myristoyltransferase (NMT) has been shown to be essential in Leishmania and subsequently validated as a drug target in Plasmodium. Herein, we discuss the use…”
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Incentivizing appropriate malaria case management in the private sector: a study protocol for two linked cluster randomized controlled trials to evaluate provider- and client-focused interventions in western Kenya and Lagos, Nigeria
Published in Implementation science : IS (20-01-2021)“…A large proportion of artemisinin-combination therapy (ACT) anti-malarial medicines is consumed by individuals that do not have malaria. The over-consumption…”
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Correction: Incentivizing appropriate malaria case management in the private sector: a study protocol for two linked cluster randomized controlled trials to evaluate provider- and client-focused interventions in western Kenya and Lagos, Nigeria
Published in Implementation science : IS (15-09-2022)Get full text
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Correction to: Incentivizing appropriate malaria case management in the private sector: a study protocol for two linked cluster randomized controlled trials to evaluate provider- and client-focused interventions in western Kenya and Lagos, Nigeria
Published in Implementation science : IS (16-03-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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A Fragment‐Based Competitive 19F LB‐NMR Platform For Hotspot‐Directed Ligand Profiling
Published in Angewandte Chemie International Edition (09-09-2024)“…Ligand binding hotspots are regions of protein surfaces that form particularly favourable interactions with small molecule pharmacophores. Targeting…”
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A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling
Published in Angewandte Chemie International Edition (09-09-2024)“…Ligand binding hotspots are regions of protein surfaces that form particularly favourable interactions with small molecule pharmacophores. Targeting…”
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A Fragment‐Based Competitive 19 F LB‐NMR Platform For Hotspot‐Directed Ligand Profiling
Published in Angewandte Chemie (09-09-2024)“…Abstract Ligand binding hotspots are regions of protein surfaces that form particularly favourable interactions with small molecule pharmacophores. Targeting…”
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10
Improved oxygen systems at hospitals in three Nigerian states: An implementation research study
Published in Pediatric pulmonology (01-06-2020)“…Introduction Hypoxemia is a life‐threatening condition and is commonly seen in children with severe pneumonia. A government‐led, NGO‐supported, multifaceted…”
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A Fragment‐Based Competitive 19F LB‐NMR Platform For Hotspot‐Directed Ligand Profiling
Published in Angewandte Chemie (09-09-2024)“…Ligand binding hotspots are regions of protein surfaces that form particularly favourable interactions with small molecule pharmacophores. Targeting…”
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Journal Article -
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A cluster-randomized trial of client and provider directed financial interventions to align incentives with appropriate case management in private medicine retailers: Results of the TESTsmART trial in Lagos, Nigeria
Published in PLOS global public health (02-07-2024)“…Malaria remains a major health priority in Nigeria. Among children with fever who seek care, less than a quarter gets tested for malaria, leading to…”
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Peptidomimetic approach to the inhibition of n-myristoyltransferase, a promising parasitic drug target
Published 01-01-2012“…N-myristoyltransferase (NMT), a ubiquitous enzyme, found in a number of organisms including fungi, parasites and humans, catalyses the irreversible transfer of…”
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Dissertation