Search Results - "Olaleye, S. B."

Attenuation of indomethacin- and HCl/ethanol-induced oxidative gastric mucosa damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seed by Olaleye, S.B, Farombi, E.O

“…Reactive oxygen species (ROS) have been implicated in the aetiology of HCl/ethanol‐ and indomethacin gastric mucosal damage. This study investigated the…”
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Cement dust inhalation induces hepato-renal dysfunction via tissue heavy metal bioaccumulation, histopathological and biochemical mechanisms by Owonikoko, M. W., Salami, A. T., Odukanmi, A. O., Emikpe, B. O., Olaleye, S. B.

“…Systemic degradations of various forms have been adduced to cement dust exposure and Inhalation is the most considerable route. We deployed inhalation method…”
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Effect of folic acid supplementation on oxidative gastric mucosa damage and acid secretory response in the rat by Ajeigbe, K O, Olaleye, S B, Oladejo, E O, Olayanju, A O

“…This study investigated the antioxidative and antisecretory properties of folic acid in the rats' stomach. Male Wistar rats were treated with 2 mg/kg diet of…”
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Hematopoietic toxicity in Wistar rats experimentally exposed to cement dust by Owonikoko, M. W., Salami, A. T., Odukanmi, A. O., Emikpe, B. O., Olaleye, S. B.

“…Cement dust (CD) is a known toxicant of both occupational and environmental impacts . Its heavy metallic and silica constituents occasion its systemic…”
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Standardized experimental model for cement dust exposure; tissue heavy metal bioaccumulation and pulmonary pathological changes in rats by Owonikoko, M.W., Emikpe, B.O., Olaleye, S.B.

“…[Display omitted] •Exposure model is a reliable method of studying pulmonary toxicity of aerosolized xenobiotics.•Deposition of particles beyond the conducting…”
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Onion (Allium cepa) extract prevents cadmium induced renal dysfunction by Ige, S F, Salawu, E O, Olaleye, S B, Adeeyo, O A, Badmus, J, Adeleke, A A

“…Cadmium (Cd), a heavy metal, is known for its adverse effects on the body. In this study, the lowering effect of Cd on renal clearance (RC) was investigated,…”
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Effect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity by Ajayi, A F, Akhigbe, R E, Adewumi, O M, Okeleji, L O, Mujaidu, K B, Olaleye, S B

“…Extracts from various morphological parts of Cryptolepis sanguinolenta are widely used traditionally in folklore medicine in many parts of the world for the…”
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Effect of magnesium pre-treatment on alloxan induced hyperglycemia in rats by Abayomi, A.I, Adewoye, E.O, Olaleye, S.B, Salami, A.T

“…Background: The role of vitamins and mineral supplementation in the prevention of diabetes mellitus is not well elucidated. Objective: The effect of prior…”
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Analgesic and anti-inflammatory properties of the leaf extracts of Anacardium occidentalis in the laboratory rodents by Onasanwo, S A, Fabiyi, T D, Oluwole, F S, Olaleye, S B

“…Anacardium occidentalis (family: Anacardiaceae) is a plant of the tropical climate widely used by folklore to treat pain and inflammation. This study was…”
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Effect of zinc treatment on intestinal motility in experimentally induced diarrhea in rats by Adeniyi, O S, Akomolafe, R O, Ojabo, C O, Eru, E U, Olaleye, S B

“…Zinc supplementation is a critical new intervention for treating diarrheal episodes in children. Recent studies suggest that administration of zinc along with…”
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Augmentation of gastric acid secretion by chloroquine and amodiaquine in the rat stomach by Ajeigbe, K O, Emikpe, B O, Olaleye, S B

“…Gastrointestinal mucosal integrity has been shown to be altered by chloroquine and amodiaquine, although the exact mechanism is not clear. Since Gastric Acid…”
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Catecholamines inhibit gastric epithelial [RGM-1] cell proliferation via β adrenoceptors by Olaleye, S B, Wu, K K K, Cho, C H

“…Catecholamines have been implicated in the modulation of normal cell growth, exerting inhibitory or excitatory control depending on the cell type. However,…”
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Anti-histaminic potential of fractions from Hedranthera barteri [(Hook F.) Pichon] root in laboratory rodents by Onasanwo, S A, Singh, G D, Olaleye, S B, Singh, S, Johri, R K

“…Hedranthera barteri, anti-inflammatory activity, anti-nociceptive activity, anti-histaminic activityL. (HB) is used in the treatment of painful conditions and…”
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Effects of amodiaquine hydrochloride and artemisinin on indomethacin-induced lipid peroxidation in rats by Ajeigbe, K O, Olaleye, S B, Nwobodo, E O

“…In this study, the effects of two antimalarials-amodiaquine hydrochloride and artemisinin were investigated in ulcerated albino rats of Wistar strain. Rats…”
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Effects of diets containing seeds of Garcinia kola (Heckel) on gastric acidity and experimental ulceration in rats by Ibironke, G. F., Olaleye, S. B., Balogun, O., Aremu, A.

“…The antiulcerogenic and gastric acid lowering effects of Garcinia kola (Heckel) seeds were investigated in male albino rats. The animals were fed for 2 weeks…”
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Analgesic activity of aqueous leaf extract of Phyllanthus amarus by Iranloye, B O, Owoyele, V B, Kelani, O R, Olaleye, S B

“…Various doses of the aqueous extract of Phyllanthus amarus (AEPA) were investigated for analgesic and anti-inflammatory activities using both thermal and…”
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Anti-inflammatory activities of a kolaviron-inhibition of nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha production in activated macrophage-like cell line by Olaleye, S B, Onasanwo, S A, Ige, A O, Wu, K K, Cho, C H

“…Kolaviron (KV), a biflavonoid fraction from the seeds of Garcinia kola has been shown to posess antiinflammatory properties in animal models of inflammation…”
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Inhibition of acute experimental colitis by a crude extract and diets containing seeds of Garcinia kola (heckel) by Olaleye, S B, Ige, S F, Onasanwo, S A, Cho, C H

“…The protective effect of Garcinia kola (GK) crude extract on acetic acid induced colitis in rats was investigated. Colitis, a form of inflammatory bowel…”
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Pretreatment effect of magnesium on alloxan induced hyperglycemia in rats by Ige, O A, Adewoye, E O, Olaleye, S B, Salami, A T

“…The role of vitamins and mineral supplementation in the management of Diabetes mellitus is not well elucidated. We therefore carried out a preliminary study to…”
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Seeds of Buchholzia coriacea in Diet Mitigate Ischemic Reperfusion-Induced Gastric Ulceration in Experimental Rats by Salami, A T, Odukanmi, O A, Faniyan, O F, Omayone, T P, Olaleye, S B

“…Buchholzia coriacea (B. coriacea) seeds, in folk medicine, have been documented to prevent gastric ulceration though the mechanism is not fully elucidated. To…”
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