Search Results - "Okuyama, Mai"

Elevated Soluble PD-L1 in Pregnant Women's Serum Suppresses the Immune Reaction by Okuyama, Mai, Mezawa, Hidetoshi, Kawai, Toshinao, Urashima, Mitsuyoshi

“…Programmed death-ligand 1 (PD-L1) is expressed not only on some cancer cells, but also on the outer surface of placental syncytiotrophoblasts, which is assumed…”
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Vitamin D Supplementation Regulates Postoperative Serum Levels of PD-L1 in Patients with Digestive Tract Cancer and Improves Survivals in the Highest Quintile of PD-L1: A Post Hoc Analysis of the AMATERASU Randomized Controlled Trial by Morita, Makoto, Okuyama, Mai, Akutsu, Taisuke, Ohdaira, Hironori, Suzuki, Yutaka, Urashima, Mitsuyoshi

“…Because vitamin D responsive elements have been found to be located in the PD-L1 gene, vitamin D supplementation was hypothesized to regulate serum PD-L1…”
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Tomatidine Reduces Palmitate‐Induced Lipid Accumulation by Activating AMPK via Vitamin D Receptor‐Mediated Signaling in Human HepG2 Hepatocytes by Kusu, Hikari, Yoshida, Hiroki, Kudo, Michiko, Okuyama, Mai, Harada, Naoki, Tsuji‐Naito, Kentaro, Akagawa, Mitsugu

“…Scope Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide, defined by hepatic over‐accumulation of lipids…”
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Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid by Harada, Naoki, Arahori, Yumi, Okuyama, Mai, Luis, Paula B., Joseph, Akil I., Kitakaze, Tomoya, Goshima, Naoki, Schneider, Claus, Inui, Hiroshi, Yamaji, Ryoichi

“…Curcumin is a yellow pigment in turmeric (Curcuma longa) with various physiological effects in the body. To elucidate the molecular mechanisms by which…”
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Fatal SARS-CoV-2 Infection among Children, Japan, January-September 2022 by Mitsushima, Shingo, Yahata, Yuichiro, Tsuchihashi, Yuuki, Ikenoue, Chiaki, Fukusumi, Munehisa, Otake, Shogo, Shimada, Tomoe, Yamagishi, Takuya, Kamiya, Hajime, Kobayashi, Yusuke, Kurosu, Hitomi, Okuyama, Mai, Morino, Saeko, Shibamura, Miho, Takanashi, Sayaka, Kamigaki, Taro, Otani, Kanako, Nakashita, Manami, Ito, Hanae, Miyazaki, Ayako, Koshiko, Masaya, Harakuni, Masanao, Onuma, Megumi, Chiba, Hiroko, Masutani, Maki, Sudani, Natsu, Satsuki, Yuka, Takara, Taketoshi, Oka, Akira, Katsuta, Tomohiro, Shimizu, Naoki, Saitoh, Akihiko, Sakamoto, Tetsuya, Suzuki, Motoi, Sunagawa, Tomimasa

“…To determine the characteristics of pediatric patients 0–19 years of age who died after onset of SARS-CoV-2 infection in Japan during January 1–September 30,…”
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Target-selective photo-degradation of AFP-L3 and selective photo-cytotoxicity against HuH-7 hepatocarcinoma cells using an anthraquinone-PhoSL hybrid by Okuyama, Mai, Ueno, Haruna, Kobayashi, Yuka, Kawagishi, Hirokazu, Takahashi, Daisuke, Toshima, Kazunobu

“…A purposefully-designed anthraquinone-Pholiota squarrosa lectin (PhoSL) hybrid effectively degraded α-fetoprotein-L3 (AFP-L3) associated with liver cancer…”
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Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin by Harada, Naoki, Okuyama, Mai, Teraoka, Yoshiaki, Arahori, Yumi, Shinmori, Yoh, Horiuchi, Hiroko, Luis, Paula B., Joseph, Akil I., Kitakaze, Tomoya, Matsumura, Shigenobu, Hira, Tohru, Yamamoto, Norio, Iuni, Takashi, Goshima, Naoki, Schneider, Claus, Inui, Hiroshi, Yamaji, Ryoichi

“…The identification of molecular targets of bioactive food components is important to understand the mechanistic aspect of their physiological functions. Here,…”
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Adverse Event Following Immunization Monitoring System in Japan by Okuyama, Mai, Kamiya, Hajime, Kamidani, Satoshi, Saitoh, Akihiko

“…Although immunization is essential for maintaining public health, adverse events following immunization (AEFI) occur at a certain rate. Therefore, it is…”
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2‐Phenylquinoline–Sugar Hybrids as Photoswitchable α‐Glucosidase Inhibitors by Kitamura, Takashi, Okuyama, Mai, Takahashi, Daisuke, Toshima, Kazunobu

“…Purpose‐designed 2‐phenylquinoline (PQ)‐sugar hybrids 1 and 2 were synthesized and evaluated for their photodegradation activities against an α‐glucosidase…”
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Vasovagal reactions after COVID-19 vaccination in Japan by Okuyama, Mai, Morino, Saeko, Tanaka, Kaori, Nakamura-Miwa, Haruna, Takanashi, Sayaka, Arai, Satoru, Ochiai, Masaki, Ishii, Koji, Suzuki, Motoi, Oka, Akira, Morio, Tomohiro, Tanaka-Taya, Keiko

“…Coronavirus disease 2019 (COVID-19) vaccine administration started in February 2021 in Japan. As of December 2021, approximately 75% of the population aged ≥12…”
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Effect of Vitamin D Supplementation on Survival of Digestive Tract Cancer Patients with Low Bioavailable 25-Hydroxyvitamin D levels: A Post Hoc Analysis of the AMATERASU Randomized Clinical Trial by Urashima, Mitsuyoshi, Okuyama, Mai, Akutsu, Taisuke, Ohdaira, Hironori, Kaji, Mutsumi, Suzuki, Yutaka

“…Vitamin D has been shown to suppress the growth of cancer cells. Cancer cells are believed to take up bioavailable 25-hydroxyvitamin D (25[OH]D) (i.e., not…”
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National seroepidemiological study of COVID‐19 after the initial rollout of vaccines: Before and at the peak of the Omicron‐dominant period in Japan by Arashiro, Takeshi, Arai, Satoru, Kinoshita, Ryo, Otani, Kanako, Miyamoto, Sho, Yoneoka, Daisuke, Kamigaki, Taro, Takahashi, Hiromizu, Hibino, Hiromi, Okuyama, Mai, Hayashi, Ai, Kikuchi, Fuka, Morino, Saeko, Takanashi, Sayaka, Wakita, Takaji, Tanaka‐Taya, Keiko, Suzuki, Tadaki, Suzuki, Motoi

“…Background Based on routine surveillance data, Japan has been affected much less by COVID‐19 compared with other countries. To validate this, we aimed to…”
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Fatal SARS-CoV-2 Infection Among Children, Japan, January–September 20221 by Mitsushima, Shingo, Yahata, Yuichiro, Tsuchihashi, Yuuki, Ikenoue, Chiaki, Fukusumi, Munehisa, Otake, Shogo, Shimada, Tomoe, Yamagishi, Takuya, Kamiya, Hajime, Kobayashi, Yusuke, Kurosu, Hitomi, Okuyama, Mai, Morino, Saeko, Shibamura, Miho, Takanashi, Sayaka, Kamigaki, Taro, Otani, Kanako, Nakashita, Manami, Ito, Hanae, Miyazaki, Ayako, Koshiko, Masaya, Harakuni, Masanao, Onuma, Megumi, Chiba, Hiroko, Masutani, Maki, Sudani, Natsu, Satsuki, Yuka, Takara, Taketoshi, Oka, Akira, Katsuta, Tomohiro, Shimizu, Naoki, Saitoh, Akihiko, Sakamoto, Tetsuya, Suzuki, Motoi, Sunagawa, Tomimasa

“…To determine the characteristics of pediatric patients 0-19 years of age who died after onset of SARS-CoV-2 infection in Japan during January 1-September 30,…”
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Effect of Avoiding Cow's Milk Formula at Birth on Prevention of Asthma or Recurrent Wheeze Among Young Children: Extended Follow-up From the ABC Randomized Clinical Trial by Tachimoto, Hiroshi, Imanari, Eiji, Mezawa, Hidetoshi, Okuyama, Mai, Urashima, Takashi, Hirano, Daishi, Gocho, Noriko, Urashima, Mitsuyoshi

“…Children with food allergies may develop asthma or recurrent wheeze. To evaluate whether asthma or recurrent wheeze among children were changed by avoiding…”
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Fatal SARS-CoV-2 Infection among Children, Japan, January-September 2022 1 by Mitsushima, Shingo, Yahata, Yuichiro, Tsuchihashi, Yuuki, Ikenoue, Chiaki, Fukusumi, Munehisa, Otake, Shogo, Shimada, Tomoe, Yamagishi, Takuya, Kamiya, Hajime, Kobayashi, Yusuke, Kurosu, Hitomi, Okuyama, Mai, Morino, Saeko, Shibamura, Miho, Takanashi, Sayaka, Kamigaki, Taro, Otani, Kanako, Nakashita, Manami, Ito, Hanae, Miyazaki, Ayako, Koshiko, Masaya, Harakuni, Masanao, Onuma, Megumi, Chiba, Hiroko, Masutani, Maki, Sudani, Natsu, Satsuki, Yuka, Takara, Taketoshi, Oka, Akira, Katsuta, Tomohiro, Shimizu, Naoki, Saitoh, Akihiko, Sakamoto, Tetsuya, Suzuki, Motoi, Sunagawa, Tomimasa

“…To determine the characteristics of pediatric patients 0-19 years of age who died after onset of SARS-CoV-2 infection in Japan during January 1-September 30,…”
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