Search Results - "Okumuş, Burak"
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Mitigation of host cell mutations and regime shift during microbial fermentation: a perspective from flux memory
Published in Current opinion in biotechnology (01-12-2020)“…Microbial engineering forces flux redistribution to accommodate higher production rates, straining the cellular supply chain and leading to growth deficiency…”
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2
A serious dermatological side effect due to vortioxetine: a case report
Published in Düşünen adam (Bakırköy Ruh ve Sinir Hastalıkları Hastanesi) (01-03-2020)“…Major depressive disorder is the second-largest healthcare problem worldwide in terms of illness-induced disability, and second-generation antidepressants are…”
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3
Understanding the effects of lysergic acid diethylamide and the importance of its prevention
Published in Health sciences review (Oxford, England) (01-09-2023)“…This review is on lysergic acid diethylamide (LSD), which has a halogenic effect and is addictive. Up to now, LSD has been used for pleasure-inducing or…”
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4
The Occurrence of Funeral Mania After Bereavement: A Case Report
Published in Medeniyet medical journal (2021)“…Stressful or traumatic life events can lead to emergence of mood episodes. Events such as migration, relocation, job loss, bankruptcy, economic loss, divorce,…”
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Segregation of molecules at cell division reveals native protein localization
Published in Nature methods (01-05-2012)“…The authors compare segregation of a protein into two daughter cells for the wild-type protein and a fluorescently tagged version, by assessing protein…”
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6
Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation
Published in Science (American Association for the Advancement of Science) (04-03-2016)“…Cells rely on the precise action of proteins that detect and repair DNA damage. However, gene expression noise causes fluctuations in protein abundances that…”
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7
Fueling protein-DNA interactions inside porous nanocontainers
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2007)“…Vesicle encapsulation offers a biologically relevant environment for many soluble proteins and nucleic acids and an optimal immobilization medium for…”
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8
Orientation dependence in fluorescent energy transfer between Cy3 and Cy5 terminally attached to double-stranded nucleic acids
Published in Proceedings of the National Academy of Sciences - PNAS (12-08-2008)“…We have found that the efficiency of fluorescence resonance energy transfer between Cy3 and Cy5 terminally attached to the 5' ends of a DNA duplex is…”
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Tracking bacterial lineages in complex and dynamic environments with applications for growth control and persistence
Published in Nature microbiology (01-06-2021)“…As bacteria transition from exponential to stationary phase, they change substantially in size, morphology, growth and expression profiles. These responses…”
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10
Quantification of very low-abundant proteins in bacteria using the HaloTag and epi-fluorescence microscopy
Published in Scientific reports (27-05-2019)“…Cell biology is increasingly dependent on quantitative methods resulting in the need for microscopic labelling technologies that are highly sensitive and…”
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11
Multiple Intermediates in SNARE-Induced Membrane Fusion
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2006)“…Membrane fusion in eukaryotic cells is thought to be mediated by a highly conserved family of proteins called SNAREs (soluble N-ethyl maleimide…”
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12
Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells
Published in Nature communications (18-05-2016)“…Many key regulatory proteins in bacteria are present in too low numbers to be detected with conventional methods, which poses a particular challenge for…”
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13
Editorial: Next-generation quantitative and synthetic biology: High-sensitivity, high-accuracy, and digital approaches
Published in Frontiers in bioengineering and biotechnology (06-02-2023)Get full text
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14
Extreme Conformational Diversity in Human Telomeric DNA
Published in Proceedings of the National Academy of Sciences - PNAS (27-12-2005)“…DNA with tandem repeats of guanines folds into G-quadruplexes made of a stack of G-quartets. In vitro, G-quadruplex formation inhibits telomere extension, and…”
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15
Single-Molecule Conformational Analysis of G-Quadruplex Formation in the Promoter DNA Duplex of the Proto-Oncogene C-Kit
Published in Journal of the American Chemical Society (20-06-2007)“…Herein we report on the single-molecule analysis of a conserved DNA quadruplex element found in the transcriptional activation site of the promoter of the…”
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16
Correction: Corrigendum: Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells
Published in Nature communications (24-06-2016)“…Nature Communications 7: Article number: 11641 (2016); Published: 18 May 2016; Updated: 24 June 2016. The original version of this Article contained an error…”
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17
Melankolik Depresyon tedavisinde venlafaksin ve agomelatinin birlikte kullanımı: Bir olgu sunumu
Published in Ege tłp bilimleri dergisi (03-08-2019)“…Major Depresif Bozukluk (MDB); yaşam boyu yaygın olarak görülmektedir(1). Klinik depresyonun bu geniş heterojenliği, depresif alt tipleri tanımlamaya yönelik…”
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18
Isolating live cells after high-throughput, long-term, time-lapse microscopy
Published in Nature methods (01-01-2020)“…Single-cell genetic screens can be incredibly powerful, but current high-throughput platforms do not track dynamic processes, and even for non-dynamic…”
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Fluidic and microfluidic tools for quantitative systems biology
Published in Current opinion in biotechnology (01-02-2014)“…Graphical abstract…”
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20
Combination of venlafaxine and agomelatine in the treatment of melancholic depression: a case report
Published in Klinik psikofarmakoloji bülteni (01-01-2019)Get full text
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