Search Results - "Okuhara, Yuji"
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Structural determination, distribution, and physiological actions of ghrelin in the guinea pig
Published in Peptides (New York, N.Y. : 1980) (01-01-2018)“…•Guinea pig ghrelin is 28 amino acids peptide mainly produced in the stomach.•N-terminal structure of guinea-pig ghrelin is unique even in mammals.•Guinea pig…”
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2
Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist
Published in Nature communications (19-07-2024)“…Sphingosine 1-phosphate receptor 1 (S1PR1), a G protein-coupled receptor, is required for lymphocyte trafficking, and is a promising therapeutic target in…”
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Spontaneous adenocarcinoma with giant cell formation in the accessory sex glands in a male Sprague-Dawley rat
Published in Journal of Toxicologic Pathology (01-10-2021)“…In this study, we report the features of an adenocarcinoma with giant cell formation spontaneously occurring in the accessory sex glands of a male 10-month-old…”
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4
Spontaneous cutaneous soft tissue sarcoma with differentiation into fibroblasts in a Sprague-Dawley rat
Published in Journal of Toxicologic Pathology (2016)“…A small mass with an ulcer was found in the skin of the dorsal cervix of a 7-month-old male Sprague-Dawley rat. Histologically, the central region of the tumor…”
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5
A comparative study of ERG responses on rabbits treated with sodium iodate using two different light stimulators; Ganzfeld dome and contact lens electrode with built-in white LED
Published in Animal Eye Research (2015)“…Electroretinography (ERG) is a useful method for the quantitative evaluation of retinal function. In the fields of clinical veterinary medicine and drug safety…”
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Spontaneous adenocarcinoma with giant cell formation in the accessory sex glands in a male Sprague-Dawley rat
Published in Journal of Toxicologic Pathology (2021)“…[Abstract] : In this study, we report the features of an adenocarcinoma with giant cell formation spontaneously occurring in the accessory sex glands of a male…”
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7
Spontaneous cutaneous soft tissue sarcoma with differentiation into fibroblasts in a Sprague-Dawley rat
Published in Journal of Toxicologic Pathology (2016)“…Abstract: A small mass with an ulcer was found in the skin of the dorsal cervix of a 7-month-old male Sprague-Dawley rat. Histologically, the central region of…”
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8
Impairment of lower jaw growth in developing zebrafish exposed to 2,3,7,8-tetrachlorodibenzo- p-dioxin and reduced hedgehog expression
Published in Aquatic toxicology (15-06-2006)“…2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) has been shown to cause a multitude of detrimental effects to developing zebrafish ( Danio rerio). Previously, we…”
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Collaborative work on evaluation of ovarian toxicity 2) Two- or four-week repeated dose studies and fertility study of mifepristone in female rats
Published in Journal of toxicological sciences (2009)“…In order to assess ovarian pathological changes and their relationship to changes in female fertility parameters, mifepristone, a progesterone receptor…”
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10
Spontaneous Subcutaneous Sarcoma in a 50-week-old Male Wistar Hannover GALAS Rat
Published in Journal of Toxicologic Pathology (2011)“…A subcutaneous mass was noted in the abdomen of a 50-week-old male Wistar Hannover GALAS rat. Histologically, the tumor was composed of vimentin-positive small…”
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11
BN.MES-Cybames Congenic Rats Manifest Focal Necrosis with Eosinophilic Infiltration in the Liver without Blood Eosinophilia
Published in Experimental Animals (2010)“…The Matsumoto Eosinophilia Shinshu (MES) rat strain develops hereditary blood eosinophilia and eosinophil-related inflammatory lesions in organs due to the…”
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12
Spontaneous Subcutaneous Sarcoma in a 50-week-old Male Wistar Hannover GALAS Rat
Published in Journal of Toxicologic Pathology (2011)“…Abstract:A subcutaneous mass was noted in the abdomen of a 50-week-old male Wistar Hannover GALAS rat. Histologically, the tumor was composed of…”
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13
Lack of Modifying Effect of Arctiin on ENU-Induced Uterine Carcinogenesis in ICR Mice
Published in Journal of Toxicologic Pathology (2007)“…The present study was performed to investigate the modifying effects of arctiin, a plant lignan isolated from Arctium lappa (burdock) seeds, on uterine…”
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Sodium Iodateを投与したウサギにおける網膜電図検査記録の比較;Ganzfeld dome型光刺激装置及び白色LED内蔵コンタクトレンズ型電極
Published in 比較眼科研究 (2015)“…網膜電図検査(ERG)は網膜機能を定量的に評価できる有用な評価系である。近年、獣医臨床及び医薬品の安全性評価においては、International Society for Clinical Electrophysiology of…”
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Identification of pheasant ghrelin and motilin and their actions on contractility of the isolated gastrointestinal tract
Published in General and comparative endocrinology (01-01-2020)“…•Motilin and ghrelin are identified in the pheasant gastrointestinal (GI) tract.•Chicken motilin contracts the pheasant GI tract in a region-dependent…”
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16
Skeletal muscle cells derived from mouse skin cultures
Published in Biochemical and biophysical research communications (23-07-2020)“…We have established a novel, simple, and highly reproducible method to generate skeletal muscle cells from mouse skin. Small pieces of skin from the back of…”
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Spontaneous adenocarcinoma with giant cell formation in the accessory sex glands in a male Sprague-Dawley rat
Published in Journal of Toxicologic Pathology (2021)“…In this study, we report the features of an adenocarcinoma with giant cell formation spontaneously occurring in the accessory sex glands of a male 10-month-old…”
Get full text
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2,3,7,8-Tetrachlorodibenzo-p-dioxin toxicity in the zebrafish embryo: Altered regional blood flow and impaired lower jaw development
Published in Toxicological sciences (01-02-2002)“…The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on regional red blood cell (RBC) perfusion rate, as an index of blood flow, and lower jaw…”
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BN.MES-Cyba(mes) congenic rats manifest focal necrosis with eosinophilic infiltration in the liver without blood eosinophilia
Published in Experimental animals (01-07-2010)“…The Matsumoto Eosinophilia Shinshu (MES) rat strain develops hereditary blood eosinophilia and eosinophil-related inflammatory lesions in organs due to the…”
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