Search Results - "Okuda, Heiwa"

Von Hippel–Lindau Disease: Molecular Pathological Basis, Clinical Criteria, Genetic Testing, Clinical Features of Tumors and Treatment by Shuin, Taro, Yamasaki, Ichiro, Tamura, Kenji, Okuda, Heiwa, Furihata, Mutsuo, Ashida, Shingo

“…von Hippel–Lindau (VHL) disease is an autosomal dominant disorder that is associated with various tumors and cysts in the central nervous system (CNS) and…”
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The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C by Okuda, Heiwa, Saitoh, Kojiro, Hirai, Syu-ichi, Iwai, Kazuhiro, Takaki, Yasuyuki, Baba, Masaya, Minato, Nagahiro, Ohno, Shigeo, Shuin, Taro

“…The von Hippel-Lindau tumor-suppressor protein (pVHL) forms a protein complex (VCB-Cul2) with elongin C, elongin B, Cul-2, and Rbx1, which functions as a…”
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Promoter Hypermethylation of the Bone Morphogenetic Protein-6 Gene in Malignant Lymphoma by DAIBATA, Masanori, NEMOTO, Yuiko, TAGUCHI, Hirokuni, BANDOBASHI, Kentaro, KOTANI, Norihiro, KURODA, Masayuki, TSUCHIYA, Mutsumi, OKUDA, Heiwa, TAKAKUWA, Tetsuya, IMAI, Shosuke, SHUIN, Taro

“…Purpose: Bone morphogenetic proteins (BMP), belonging to the transforming growth factor-β superfamily, are important regulators of cell growth,…”
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Downregulation of Cap43 gene by von Hippel‐Lindau tumor suppressor protein in human renal cancer cells by Masuda, Katsuaki, Ono, Mayumi, Okamoto, Masahiro, Morikawa, Wataru, Otsubo, Michihiro, Migita, Toshiro, Tsuneyoshi, Masazumi, Okuda, Heiwa, Shuin, Taro, Naito, Seiji, Kuwano, Michihiko

“…We previously identified 9 genes (i.e., thymosin β4, secreted protein acidic and rich in cysteine, Cap43, ceruloplasmin, serum amyloid A, heat shock protein…”
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Detection of Circulating Cancer Cells with von Hippel-Lindau Gene Mutation in Peripheral Blood of Patients with Renal Cell Carcinoma by ASHIDA, Shingo, OKUDA, Heiwa, CHIKAZAWA, Masakazu, TANIMURA, Masanobu, SUGITA, Osamu, YAMAMOTO, Yukio, NAKAMURA, Syoichiro, MORIYAMA, Masatoshi, SHUIN, Taro

“…Mutations of the von Hippel-Lindau (VHL) tumor suppressor gene have been detected in up to 60% of sporadic clear cell renal carcinomas (RCCs). Even patients…”
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Cloning, sequencing, and overexpression in Escherichia coli of a phenylserine dehydratase gene from Ralstonia [Pseudomonas] pickettii PS22 by Okuda, H. (Kochi Univ. (Japan)), Nagata, S, Misono, H

“…The structural gene coding for phenylserine dehydratase from Ralstonia pickettii PS22 was cloned into Escherichia coli cells, and the nucleotide sequence was…”
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A Novel Phenylserine Dehydratase from Pseudomonas pickettii PS22: Purification, Characterization, and Sequence of Its Phosphopyridoxyl Peptide by Okuda, Heiwa, Nagata, Shinji, Misono, Haru

“…A novel phenylserine dehydratase [EC 4.2.1.-], which catalyzes the deamination of L-threo-3-phenylserine to yield phenylpyruvate and ammonia, was purified to…”
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Occurrence of an Inducible Phenylserine Dehydratase in Pseudomonas pickettii PS22 Isolated from Soil by Misono, Haruo, Okuda, Heiwa, Shin, Koichiro, Nagata, Shinji, Nagasaki, Susumu

“…We found an inducible phenylserine dehydratase [EC 4.2.1.-] in a soil bacterium identified as Pseudomonas pickettii PS22. The enzyme catalyzes the deamination…”
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Ternary complex formation of pVHL, elongin B and elongin C visualized in living cells by a fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy technique by Kinoshita, Koshi, Goryo, Kenji, Takada, Mamiko, Tomokuni, Yosuke, Aso, Teijiro, Okuda, Heiwa, Shuin, Taro, Fukumura, Hiroshi, Sogawa, Kazuhiro

“…The tumor suppressor von Hippel-Lindau (VHL) gene product forms a complex with elongin B and elongin C, and acts as a recognition subunit of a ubiquitin E3…”
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The von Hippel–Lindau tumour-suppressor protein interaction with protein kinase Cδ by Iturrioz, Xavier, Durgan, Joanne, Calleja, Véronique, Larijani, Banafshé, Okuda, Heiwa, Whelan, Richard, Parker, Peter J.

“…The VHL (von Hippel–Lindau) tumour-suppressor protein forms a multi-protein complex [VCB (pVHL–elongin C–elongin B)–Cul-2 (Cullin-2)] with elongin C, elongin…”
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HIF-1α-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway by Wang, Feng, Sekine, Hiroki, Kikuchi, Yasuo, Takasaki, Chikahisa, Miura, Chisa, Heiwa, Okuda, Shuin, Taro, Fujii-Kuriyama, Yoshiaki, Sogawa, Kazuhiro

“…We have investigated inhibitory mechanisms of hypoxic activation of HIF-1α by nitric oxide (NO). Using a Hep3B cell-derived cell line, HRE7 cells, we found…”
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Emergency pancreatoduodenectomy for pancreatic metastasis from renal cell carcinoma in a patient with von hipple-lindau disease : A case report by MAEDA, Hiromichi, OKABAYASHI, Takehiro, SHUIN, Taro, KOBAYASHI, Michiya, ARAKI, Keijiro, KOHSAKI, Takuhiro, NISHIMORI, Isao, ONISHI, Saburo, ITO, Satoshi, OGAWA, Yasuhiro, OKUDA, Heiwa

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The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cd by Iturrioz, Xavier, Durgan, Joanne, Calleja, Veronique, Larijani, Banafshe, Okuda, Heiwa, Whelan, Richard, Parker, Peter J

“…The VHL (von Hippel-Lindau) tumour-suppressor protein forms a multi-protein complex [VCB (pVHL-elongin C-elongin B)-Cul-2 (Cullin-2)] with elongin C, elongin…”
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The Von Hippel-Lindau tumor-suppressor protein interaction with protein kinase C {delta} by Iturrioz, Xavier, Durgan, Joanne, Calleja, Véronique, Larijani, Banafshé, Okuda, Heiwa, Whelan, Richard H, Parker, Peter J

“…The Von Hippel-Lindau tumor-suppressor protein (pVHL) forms a multi-protein complex (VCB-Cul2) with elongin C, elongin B, Cul-2, and Rbx1, acting as a…”
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von Hippel-Lindau protein promotes the assembly of actin and vinculin and inhibits cell motility by KAMADA, Masayuki, SUZUKI, Keiji, KATO, Yasumasa, OKUDA, Heiwa, SHUIN, Taro

“…Mutation of the von Hippel-Lindau (VHL) gene is responsible for familial and sporadic renal cell carcinomas as well as for cancers in many other organs…”
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Direct Interaction of the β-Domain of VHL Tumor Suppressor Protein with the Regulatory Domain of Atypical PKC Isotypes by Okuda, Heiwa, Hirai, Syu-ichi, Takaki, Yasuyuki, Kamada, Masayuki, Baba, Masaya, Sakai, Naoki, Kishida, Takeshi, Kaneko, Shigeki, Yao, Masahiro, Ohno, Shigeo, Shuin, Taro

“…VHL tumor suppressor protein contains two domains, α and β. The α-domain is involved in the formation of a large protein complex suggested to be involved in…”
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Hypermethylation of the RASSF1A tumor suppressor gene in Japanese clear cell renal cell carcinoma by Tokinaga, Kenji, Okuda, Heiwa, Nomura, Asuka, Ashida, Shingo, Furihata, Mutsuo, Shuin, Taro

“…Hypermethylation associated inactivation of RASSF1A tumor suppressor gene at chromosome 3p21.3 has been observed in several human malignancies. Relatively high…”
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Emergency pancreatoduodenectomy for pancreatic metastasis from renal cell carcinoma in a patient with von Hippel-Lindau disease: a case report by Maeda, Hiromichi, Okabayashi, Takehiro, Kobayashi, Michiya, Araki, Keijiro, Kohsaki, Takuhiro, Nishimori, Isao, Onishi, Saburo, Ito, Satoshi, Ogawa, Yasuhiro, Okuda, Heiwa, Shuin, Taro

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Renal cell carcinoma- and pheochromocytoma-specific altered gene expression profiles in VHL mutant clones by Tsuchiya, Mutsumi I, Okuda, Heiwa, Takaki, Yasuyuki, Baba, Masaya, Hirai, Syu-Ichi, Ohno, Shigeo, Shuin, Taro

“…Von Hippel-Lindau (VHL) disease is associated with various missense germline mutations in the VHL tumor suppressor gene. Some are associated with type 1 VHL…”
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HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway by Wang, Feng, Sekine, Hiroki, Kikuchi, Yasuo, Takasaki, Chikahisa, Miura, Chisa, Heiwa, Okuda, Shuin, Taro, Fujii-Kuriyama, Yoshiaki, Sogawa, Kazuhiro

“…We have investigated inhibitory mechanisms of hypoxic activation of HIF-1alpha by nitric oxide (NO). Using a Hep3B cell-derived cell line, HRE7 cells, we found…”
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