Search Results - "Okoye, Festus B. C."

Phytochemical analysis, hepatoprotective and antioxidant activity of Alchornea cordifolia methanol leaf extract on carbon tetrachloride-induced hepatic damage in rats by Osadebe, Patience O, Okoye, Festus B C, Uzor, Philip F, Nnamani, Nneka R, Adiele, Ijeoma E, Obiano, Nkemakonam C

“…To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A. cordifolia) leaf extract. Various solvent fractions of the methanol…”
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Cytotoxic effect and antioxidant activity of pterocarpans from Millettia aboensis root by Ajaegbu, Eze E, Eboka, Chuks J, Okoye, Festus B C, Proksch, Peter

“…Chemical analysis of the methanol extract of the root bark of led to the isolation of homopterocarpin ( ), secundiflorol I ( ), and maackain ( ). The…”
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Editorial: Fungal Bioactive Metabolites of Pharmacological Relevance by Fasinu, Pius S., Okoye, Festus B. C., Abiodun, Oyindamola O., Kamdem, Ramsay S. T., Ogbole, Omonike O.

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Orthosporin, a major component of the fermentation product of Lasiodiplodia theobromae - an endophytic fungus of Musa paradisiaca as a potential antimicrobial agent by OKEZIE, Ugochukwu M., EZE, Peter M., OKOYE, Festus B. C., ESIMONE, Charles O.

“…Endophytic fungi remain an unexplored reservoir of chemical diversity, and have become the primary focus is several bio-prospecting programs. This study was…”
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A new antibacterial benzophenone glycoside from Psidium guajava (Linn.) leaves by Ukwueze, Stanley E., Osadebe, Patience O., Okoye, Festus B.C.

“…Bioactivity-guided fractionation of methanol extract from the leaves of Psidium guajava L. (Myrtaceae) yielded a new benzophenone glycoside, Guajaphenone A (2)…”
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Antibacterial, anti-inflammatory and peroxidase-mediated cyclooxygenase-1 inhibitory properties of Fusarium solani extract by Ngwoke, Kenneth, Tochukwu, Nwalusiuka, Ekwealor, Chinechem, Nwankwo, Valerie, Obi-Okafor, Uju, Izundu, Chisom, Okoye, Festus B. C., Esimone, Charles, Proksch, Peter, Situ, Chen

“…Context: Nigerian soil fungi population is unexplored. It is hypothesized that they harbour new bioactive chemicals. This hypothesis is based on the large…”
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Secondary metabolites of a marine-derived Penicillium ochrochloron by EZE, Peter M., GAO, Ying, LIU, Yang, Van GEELEN, Lasse, EJIKEUGWU, Chika P., ESIMONE, Charles O., OKOYE, Festus B. C., PROKSCH, Peter, KALSCHEUER, Rainer

“…Extremophilic fungi have received considerable attention recently as new promising sources of biologically active compounds with potential pharmaceutical…”
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Anti-inflammatory and membrane-stabilizing stigmastane steroids from Alchornea floribunda leaves by Okoye, Festus B C, Osadebe, Patience O, Proksch, Peter, Edrada-Ebel, Ru Angelie, Nworu, Chukwuemeka S, Esimone, Charles O

“…Alchornea floribunda (Euphorbiaceae) leaves are widely used in African ethnomedicine for the management of acute and chronic inflammatory disorders. In the…”
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Evaluation of the antimalarial and CD4+ T-cell modulatory effects of leaf methanol extract of Phyllanthus muellerianus (Kuntze) Exell (Phyllanthaceae) in Plasmodium berghei-infected mice by Ofokansi, Martha N., Nwoye, Eze C., Ugwah-Oguejiofor, Chinenye J., Okoye, Festus B.C., Akah, Peter A.

“…Phyllanthus muellerianus (Kunze) Exell, a member of the Phyllanthaceae family, is a medicinal plant widely distributed in Africa. Decoctions from the leaves…”
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Antimicrobial activities of secondary metabolites of endophytic fungi isolated from Catharanthus roseus by Akpotu, Mark O., Eze, Peter M., Abba, Chika C., Umeokoli, Blessing O., Nwachukwu, Charles U., Okoye, Festus B. C., Esimone, Charles O.

“…Introduction: Recently, several endophytes have been shown to possess the potentials to synthesize novel bioactive compounds that have found use for drug…”
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Flavonoid glycosides from Olax mannii: Structure elucidation and effect on the nuclear factor kappa B pathway by Okoye, Festus B.C., Sawadogo, Wamtinga Richard, Sendker, Jandirk, Aly, Amal H., Quandt, Bettina, Wray, Victor, Hensel, Andreas, Esimone, Charles O., Debbab, Abdessamad, Diederich, Marc, Proksch, Peter

“…Olax mannii Oliv. (Olacaceae) is among the many medicinal plants used in Nigeria for the ethnomedicinal management of both cancer and inflammation. Such plants…”
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R-Hexitronic acid, a new tetronic acid derivative isolated from a soil fungus FG9RK by Ngwoke, Kenneth G., El-Kashef, Dina H., Daletos, Georgios, Ancheeva, Elena, Liu, Zhen, Okoye, Festus B. C., Esimone, Charles O., Proksch, Peter

“…A new tetronic acid derivative (1) together with terrestric acid (2), a known metabolite of Penicillium species, was isolated from the soil fungus, FG9RK…”
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Substituted l-tryptophan-l-phenyllactic acid conjugates produced by an endophytic fungus Aspergillus aculeatus using an OSMAC approach by Wang, Hao, Eze, Peter M, Höfert, Simon-Patrick, Janiak, Christoph, Hartmann, Rudolf, Okoye, Festus B C, Esimone, Charles O, Orfali, Raha S, Dai, Haofu, Liu, Zhen, Proksch, Peter

“…The endophytic fungus isolated from leaves of the papaya plant was fermented on solid rice medium, yielding a new l-tryptophan-l-phenyllactic acid conjugate…”
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Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis by Okoye, Theophine C., Akah, Peter A., Omeje, Edwin O., Okoye, Festus B.C., Nworu, Chukwuemeka S.

“…The herbal preparations of Annona senegalensis Pers. (Annonaceae) root bark are used in Nigerian ethnomedicine for the treatment of epilepsy and febrile…”
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Screening of endophytic fungal metabolites from Cola nitida leaves for antimicrobial activities against clinical isolates of Pseudomonas aeruginosa by Nwobodo, David C., Ihekwereme, Chibueze P., Okoye, Festus B. C.

“…Endophytic fungi of selected Nigerian plants are important sources of bioactive products with enormous potentials for the discovery of new drug molecules for…”
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A new benzophenone glycoside from the leaves of Mitracarpus villosus by Ngwoke, Kenneth G., Orame, Njideka, Liu, Shuai, Okoye, Festus B. C., Daletos, Georgios, Proksch, Peter

“…A new benzophenone glycoside, mitraphenone A (1), together with three known compounds (2-4) were isolated from the leaves of the traditionally used medicinal…”
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Modulation of intracellular expression of IFNγ and IL-2 in culture of splenic T lymphocytes by some flavonoid glycosides of Alchornea floribunda by Okoye, Festus B. C., Odimegwu, Damian Chukwu, Nworu, Chukwuemeka Sylvester, Agbo, Matthias Onyebuchi, Esimone, Charles Okechukwu, Osadebe, Patience Ogoamaka, Proksch, Peter

“…Context Alchornea floribunda Müll. Arg. (Euphorbiaceae) leaves are widely used in ethnomedicine for the management of rheumatism, arthritis and toothache…”
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Screening of metabolites from endophytic fungi of some Nigerian medicinal plants for antimicrobial activities by Eze, Peter M., Nnanna, Joy C., Okezie, Ugochukwu, Buzugbe, Happiness S., Abba, Chika C., Chukwunwejim, Chidimma R., Okoye, Festus B. C., Esimone, Charles O.

“…Endophytic fungi associated with Nigerian plants have recently generated significant interest in drug discovery programmes due to their immense potential to…”
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Immunomodulatory and immunorestorative activities of β-D-glucan-rich extract and polysaccharide fraction of mushroom, Pleurutus tuberregium by Nworu, Chukwuemeka S, Ihim, Stella A, Okoye, Festus B C, Esimone, Charles O, Adikwu, Michael U, Akah, Peter A

“…Some edible mushrooms are reputed to possess useful medicinal properties which are related to their ability to modulate the protective responses of the immune…”
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Toxic, but beneficial compounds from endophytic fungi of Carica papaya by Eze, Peter M., Abonyi, Dominic O., Abba, Chika C., Proksch, Peter, Okoye, Festus B. C., Esimone, Charles O.

“…Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating…”
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