Search Results - "Okoro, Nkwachukwu Oziamara"
-
1
Gene therapy in PIDs, hemoglobin, ocular, neurodegenerative, and hemophilia B disorders
Published in Open life sciences (03-05-2021)“…A new approach is adopted to treat primary immunodeficiency disorders, such as the severe combined immunodeficiency (SCID; e.g., adenosine deaminase SCID…”
Get full text
Journal Article -
2
MasitinibL shows promise as a drug-like analog of masitinib that elicits comparable SARS-Cov-2 3CLpro inhibition with low kinase preference
Published in Scientific reports (28-04-2023)“…SARS-CoV-2 infection has led to several million deaths worldwide and ravaged the economies of many countries. Hence, developing therapeutics against SARS-CoV-2…”
Get full text
Journal Article -
3
Bioactive Phytochemicals with Anti-Aging and Lifespan Extending Potentials in Caenorhabditis elegans
Published in Molecules (Basel, Switzerland) (02-12-2021)“…In the forms of either herbs or functional foods, plants and their products have attracted medicinal, culinary, and nutraceutical applications due to their…”
Get full text
Journal Article -
4
Polysaccharides Extracted from Dendrobium officinale Grown in Different Environments Elicit Varying Health Benefits in Caenorhabditis elegans
Published in Nutrients (06-06-2023)“…is one of the most widely used medicinal herbs, especially in Asia. In recent times, the polysaccharide content of has garnered attention due to the numerous…”
Get full text
Journal Article -
5
New advances in protein engineering for industrial applications: Key takeaways
Published in Open life sciences (17-06-2024)“…Recent advancements in protein/enzyme engineering have enabled the production of a diverse array of high-value compounds in microbial systems with the…”
Get full text
Journal Article -
6
FTO gene expression in diet-induced obesity is downregulated by Solanum fruit supplementation
Published in Open life sciences (15-06-2022)“…The Fat Mass and Obesity-associated (FTO) gene has been shown to play an important role in developing obesity, manifesting in traits such as increased body…”
Get full text
Journal Article -
7
Characterization of the SARS-CoV-2 coronavirus X4-like accessory protein
Published in Egyptian Journal of Medical Human Genetics (08-05-2021)“…Background The novel coronavirus SARS-CoV-2 is currently a global threat to health and economies. Therapeutics and vaccines are in rapid development; however,…”
Get full text
Journal Article -
8
Investigation of the MDM2-binding potential of de novo designed peptides using enhanced sampling simulations
Published in International journal of biological macromolecules (01-06-2024)“…The tumor suppressor p53 plays a crucial role in cellular responses to various stresses, regulating key processes such as apoptosis, senescence, and DNA…”
Get full text
Journal Article -
9
Polysaccharides Extracted from IDendrobium officinale/I Grown in Different Environments Elicit Varying Health Benefits in ICaenorhabditis elegans/I
Published in Nutrients (01-06-2023)“…Dendrobium officinale is one of the most widely used medicinal herbs, especially in Asia. In recent times, the polysaccharide content of D. officinale has…”
Get full text
Journal Article -
10
Ganoderma lucidum methyl ganoderate E extends lifespan and modulates aging-related indicators in Caenorhabditis elegans
Published in Food & function (22-01-2024)“…Methyl Ganoderate E (MGE) is a triterpenoid derived from (Reishi), an edible mushroom, commonly processed into food forms such as soups, drinks, culinary…”
Get more information
Journal Article