Search Results - "Okonkwo, Linda"

Daratumumab plus lenalidomide and dexamethasone in relapsed/refractory multiple myeloma: extended follow-up of POLLUX, a randomized, open-label, phase 3 study by Bahlis, Nizar J., Dimopoulos, Meletios A., White, Darrell J., Benboubker, Lotfi, Cook, Gordon, Leiba, Merav, Ho, P. Joy, Kim, Kihyun, Takezako, Naoki, Moreau, Philippe, Kaufman, Jonathan L., Krevvata, Maria, Chiu, Christopher, Qin, Xiang, Okonkwo, Linda, Trivedi, Sonali, Ukropec, Jon, Qi, Ming, San-Miguel, Jesus

“…In POLLUX, daratumumab (D) plus lenalidomide/dexamethasone (Rd) reduced the risk of disease progression or death by 63% and increased the overall response rate…”
Get full text

Electromagnetic Navigational Bronchoscopy for the Diagnosis of Pulmonary Amyloidosis by Desai, Anish, MBBS, Aristide, Guy, MD, Desai, Amishi, MBBS, Okonkwo, Linda, MBBS, Mathew, Joseph, MBBS, Balachandran Nair, Girish, MD

Get full text

Intravascular large cell lymphoma of NK/T-cell type, EBV positive by Okonkwo, Linda, Jaffe, Elaine S.

Get full text

Treatment patterns, economic burden, and overall survival in US Medicare Advantage beneficiaries newly diagnosed with acute myeloid leukemia (AML) in 2015-2020 by Huntington, Scott F., Ingham, Michael P., Okonkwo, Linda, Singh, Ajaybir, Wang, Ruibin, Ammann, Eric M.

“…The present study assessed changes in patient management, economic burden, and overall survival (OS) in a contemporary cohort of 2775 US Medicare Advantage…”
Get full text

7 Month Old With Congenital Nephrotic Syndrome Due To Novel 5 Base Pair Deletion in the WT1 Gene by Okonkwo, Linda, Saha, Aniket, Pawar, Shashi, Donovan, Virginia

Get full text

Evaluation of Sustained Minimal Residual Disease (MRD) Negativity in Relapsed/Refractory Multiple Myeloma (RRMM) Patients (Pts) Treated with Daratumumab in Combination with Lenalidomide Plus Dexamethasone (D-Rd) or Bortezomib Plus Dexamethasone (D-Vd): Analysis of Pollux and Castor by Avet-Loiseau, Hervé, San-Miguel, Jesus F, Casneuf, Tineke, Iida, Shinsuke, Lonial, Sagar, Usmani, Saad Z., Spencer, Andrew, Moreau, Philippe, Plesner, Torben, Weisel, Katja, Ukropec, Jon, Okonkwo, Linda, Trivedi, Sonali, Velas, Christopher Joseph, Qin, Xiang, Qi, Ming, Chiu, Christopher, Bahlis, Nizar

“…▪ Introduction: Daratumumab (DARA) is a human IgGκ mAb targeting CD38 with both direct on-tumor and immunomodulatory mechanisms of action, and has been…”
Get full text

Three-Year Follow up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Relapsed or Refractory Multiple Myeloma (RRMM) by Bahlis, Nizar, Dimopoulos, Meletios A, White, Darrell J, Benboubker, Lotfi, Cook, Gordon, Leiba, Merav, Ho, P. Joy, Kim, Kihyun, Takezako, Naoki, Moreau, Philippe, Krevvata, Maria, Chiu, Christopher, Qin, Xiang, Okonkwo, Linda, Trivedi, Sonali, Qi, Ming, San-Miguel, Jesus F

“…▪ Introduction: Daratumumab is a human, CD38-targeted, IgGκ monoclonal antibody with both direct on-tumor and immunomodulatory mechanisms of action. In the…”
Get full text

Efficacy of Daratumumab in Combination with Standard of Care Regimens in Lenalidomide-Exposed or -Refractory Patients with Relapsed/Refractory Multiple Myeloma (RRMM): Analysis of the Castor, Pollux, and MMY1001 Studies by Usmani, Saad Z., Mateos, Maria-Victoria, Lentzsch, Suzanne, Quach, Hang, Capra, Marcelo, Ovilla, Roberto, Jo, Jae-Cheol, Shin, Ho-Jin, Sonneveld, Pieter, Qi, Ming, Amin, Himal, Wang, Jianping, Qin, Xiang, Okonkwo, Linda, Ukropec, Jon, Trivedi, Sonali, Suzuki, Kenshi, Dimopoulos, Meletios A, Cavo, Michele, Nooka, Ajay K, Chari, Ajai, Facon, Thierry

“…Introduction: The use of lenalidomide (len) in the treatment of newly diagnosed multiple myeloma (NDMM) as induction and/or maintenance therapy is increasing…”
Get full text

Abstract 3813: Development of JNJ-64164711, a low fucose anti-GITR antibody for enhanced depletion of tumor regulatory T cells (Tregs) by Holland, Cam V., Kehoe, John, Hailey, Judith, Nanjunda, Rupesh, Lacy, Eilyn, Ernst, Robin, Zhang, Di, Wu, Sam, Teplyakov, Alexey, Li, Weimin, Kinder, Michelle, Thompson, Edward W., Wilkinson, Patrick, Wong, Jackson, Chu, Gerald, Okonkwo, Linda, Alvarez, John D., Nguyen, Anhco, Grewal, Iqbal S., Chatterjee-Kishore, Moitreyee, Salvati, Mark, Gottardis, Marco

“…Abstract Background: Checkpoint blockade of PD-1/PDL-1 or CTLA-4 has demonstrated clinical benefit in a subset of cancer patients (pts). To further improve the…”
Get full text

Postoperative adhesion formation in a rabbit model: monopolar electrosurgery versus ultrasonic scalpel by Vetere, Patrick F, Lazarou, George, Apostol, Radu, Khullar, Poonam, Okonkwo, Linda, Nezhat, Farr

“…To determine if surgery using ultrasonic energy for dissection results in less adhesion formation than monopolar electrosurgical energy in the late (8 weeks)…”
Get full text

Megakaryoblastic Myeloid Sarcoma: Case Series of Lytic Bone Lesions With Radiographic and Histologic Correlation by Okonkwo, Linda, Donovan, Virginia, D'Abreo, Nina, Brooks, Michael K.

Get full text

Nonamyloid tumoral light-chain-deposition disease (aggregoma) of the paraspinal region by Singh, Ayushi, Okonkwo, Linda, Hoffmann, Jason C., Mazzie, Joseph P., Baadh, Amanjit S.

“…Aggregomas are rare localized masses of monoclonal nonamyloid immunoglobulin light-chain deposits. To date, there have been only a few reports of isolated…”
Get full text