Search Results - "Okita, Akiko"
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Transcriptional silencing of centromere repeats by heterochromatin safeguards chromosome integrity
Published in Current genetics (01-10-2019)“…The centromere region of chromosomes consists of repetitive DNA sequences, and is, therefore, one of the fragile sites of chromosomes in many eukaryotes. In…”
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Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation
Published in Nucleic acids research (15-12-2016)“…Centromeres consist of DNA repeats in many eukaryotes. Non-allelic homologous recombination (HR) between them can result in gross chromosomal rearrangements…”
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Regulation of mitotic recombination between DNA repeats in centromeres
Published in Nucleic acids research (02-11-2017)“…Centromeres that are essential for faithful segregation of chromosomes consist of unique DNA repeats in many eukaryotes. Although recombination is…”
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Regulation of mitotic recombination between DNA repeats in centromeres
Published in Nucleic acids research (16-02-2018)Get full text
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Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription
Published in Communications biology (11-01-2019)“…Heterochromatin, characterized by histone H3 lysine 9 (H3K9) methylation, assembles on repetitive regions including centromeres. Although centromeric…”
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Dietary Intake of Polyunsaturated Fatty Acids and Diabetic Nephropathy: Cohort Analysis of the Tsugaru Study
Published in In vivo (Athens) (01-07-2023)“…Diabetic nephropathy (DN) is the leading cause of end-stage renal failure and its incidence continues to increase. To decrease this, a countermeasure from an…”
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Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription
Published in Communications biology (11-01-2019)“…Heterochromatin, characterized by histone H3 lysine 9 (H3K9) methylation, assembles on repetitive regions including centromeres. Although centromeric…”
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