Search Results - "Okina, Elena"
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Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention
Published in Journal of experimental & clinical cancer research (01-07-2022)“…Abstract Background One of the most malignant tumors in men is prostate cancer that is still incurable due to its heterogenous and progressive natures. Genetic…”
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Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels
Published in The Journal of cell biology (28-09-2015)“…Transmembrane heparan sulfate proteoglycans regulate multiple aspects of cell behavior, but the molecular basis of their signaling is unresolved. The major…”
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Amino acid transporters within the solute carrier superfamily: Underappreciated proteins and novel opportunities for cancer therapy
Published in Molecular metabolism (Germany) (01-06-2024)“…Solute carrier (SLC) transporters, a diverse family of membrane proteins, are instrumental in orchestrating the intake and efflux of nutrients including amino…”
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Delineating the role of nuclear receptors in colorectal cancer, a focused review
Published in Discover. Oncology (19-02-2024)“…Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally, causing a significant number of deaths, surpassing 0.9 million in the year…”
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Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems
Published in Stem cell reports (11-10-2016)“…A major hurdle for in vitro culturing of primary endothelial cells (ECs) is that they readily dedifferentiate, hampering their use for therapeutic…”
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The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer
Published in Cell death discovery (29-09-2024)“…Lung cancer is a severe challenge to the health care system with intrinsic resistance to first and second-line chemo/radiotherapies. In view of the sterile…”
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