Search Results - "Okeke, Malachy Ifeanyi"

Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution by Alakunle, Emmanuel, Moens, Ugo, Nchinda, Godwin, Okeke, Malachy Ifeanyi

“…Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state)…”
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Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus by Diaz-Cánova, Diana, Moens, Ugo, Brinkmann, Annika, Nitsche, Andreas, Okeke, Malachy Ifeanyi

“…Modified vaccinia virus Ankara (MVA) has been widely tested in clinical trials as recombinant vector vaccine against infectious diseases and cancers in humans…”
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Genomic Sequencing and Analysis of a Novel Human Cowpox Virus With Mosaic Sequences From North America and Old World Orthopoxvirus by Diaz-Cánova, Diana, Moens, Ugo L, Brinkmann, Annika, Nitsche, Andreas, Okeke, Malachy Ifeanyi

“…Orthopoxviruses (OPXVs) not only infect their natural hosts, but some OPXVs can also cause disease in humans. Previously, we partially characterized an OPXV…”
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A comprehensive review of monkeypox virus and mpox characteristics by Alakunle, Emmanuel, Kolawole, Daniel, Diaz-Cánova, Diana, Alele, Faith, Adegboye, Oyelola, Moens, Ugo, Okeke, Malachy Ifeanyi

“…Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa,…”
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Genomic Sequencing and Phylogenomics of Cowpox Virus by Diaz-Cánova, Diana, Mavian, Carla, Brinkmann, Annika, Nitsche, Andreas, Moens, Ugo, Okeke, Malachy Ifeanyi

“…Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia,…”
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The epidemiological trend of monkeypox and monkeypox-varicella zoster viruses co-infection in North-Eastern Nigeria by Stephen, Roland, Alele, Faith, Olumoh, Jamiu, Tyndall, Jennifer, Okeke, Malachy Ifeanyi, Adegboye, Oyelola

“…Monkeypox (MPX) is endemic in Nigeria, but it was first reported in Adamawa state, North-Eastern Nigeria, in January 2022. There are currently 172 cases of MPX…”
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A critical evaluation of Nigeria’s response to the first wave of COVID-19 by Jacobs, Ezekiel Damilare, Okeke, Malachy Ifeanyi

“…Background The first wave of the Coronavirus Disease 2019 (COVID-19) pandemic began when the first index case was reported in Nigeria on the 27th of February…”
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Corrigendum: The epidemiological trend of monkeypox and monkeypox-varicella zoster viruses co-infection in North-Eastern Nigeria by Stephen, Roland, Alele, Faith, Olumoh, Jamiu, Tyndall, Jennifer, Okeke, Malachy Ifeanyi, Adegboye, Oyelola

“…[This corrects the article DOI: 10.3389/fpubh.2022.1066589.]…”
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Orthopoxvirus DNA in Eurasian lynx, Sweden by Tryland, Morten, Okeke, Malachy Ifeanyi, Af Segerstad, Carl Hård, Mörner, Torsten, Traavik, Terje, Ryser-Degiorgis, Marie Pierre

“…Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans,…”
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The myth that Nigerians are immune to SARS-CoV-2 and that COVID-19 is a hoax are putting lives at risk by Aiyewumi, Oluwadamilola, Okeke, Malachy Ifeanyi

“…[...]in an effort to quell this tide of disinformation and soothe the fears of ignorant Nigerians buried in conspiracy theories, conventional mass media…”
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Bioinformatic identification of monkeypox virus phylogenetic gene trees that are representative of its whole-genome phylogenetic tree by Akpan, El-Miracle Idorenyin, Diaz-Cánova, Diana, Okeke, Malachy Ifeanyi

“…Phylogenetic analysis based on whole-genome sequences is the gold standard for monkeypox virus (MPXV) phylogeny. However, genomic epidemiology capability and…”
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Phylogenetic and Mutational Analysis of Lassa Virus Strains Isolated in Nigeria: Proposal for an In Silico Study by Kolawole, Daniel, Raji, Hayatu, Okeke, Malachy Ifeanyi

“…In 2018, the total number of Lassa fever cases in Nigeria was significantly higher than that observed in previous years. Hence, studies had attempted to…”
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Survey of attitude to human genome modification in Nigeria by Jibrilla, Maryam, Raji, Hayatu, Okeke, Malachy Ifeanyi

“…Gene editing and mitochondrial replacement therapy (MRT) are biotechnologies used to modify the host nuclear and mitochondrial DNA, respectively. Gene editing…”
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A naturally occurring cowpox virus with an ectromelia virus A-type inclusion protein gene displays atypical A-type inclusions by Okeke, Malachy Ifeanyi, Hansen, Hilde, Traavik, Terje

“…► A cowpox virus from a human patient in Norway produced atypical A-type inclusions. ► The atip gene of the cowpox virus is identical to that of ectromelia…”
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CRISPR/Cas9-Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development by Okoli, Arinze, Okeke, Malachy I, Tryland, Morten, Moens, Ugo

“…The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches. Its…”
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Antibacterial activity of Citrus limonum fruit juice extract by Okeke, Malachy Ifeanyi, Okoli, Arinze Stanley, Eze, Edith Nneka, Ekwume, Grace Chinwe, Okosa, Evangelin Uchena, Iroegbu, Christian Ukwuoma

“…The fruit juice extract of Citrus limonum was investigated for antibacterial activity. The antibacterial activity of the extract on ten strains of bacteria was…”
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Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps? by Okeke, Malachy I, Okoli, Arinze S, Diaz, Diana, Offor, Collins, Oludotun, Taiwo G, Tryland, Morten, Bøhn, Thomas, Moens, Ugo

“…Modified vaccinia virus Ankara (MVA) is the vector of choice for human and veterinary applications due to its strong safety profile and immunogenicity in vivo…”
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Molecular characterization and phylogenetics of Fennoscandian cowpox virus isolates based on the p4c and atip genes by Okeke, Malachy Ifeanyi, Okoli, Arinze Stanley, Nilssen, Øivind, Moens, Ugo, Tryland, Morten, Bøhn, Thomas, Traavik, Terje

“…Cowpox virus (CPXV), a rodent-borne Orthopoxvirus (OPV) that is indigenous to Eurasia can infect humans, cattle, felidae and other animals. Molecular…”
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Comparison and phylogenetic analysis of cowpox viruses isolated from cats and humans in Fennoscandia by Hansen, Hilde, Okeke, Malachy Ifeanyi, Nilssen, Øivind, Traavik, Terje

“…Cowpox virus (CPXV), a member of the genus Orthopoxvirus (OPV), has reservoirs in small mammals and may cause disease in humans, felidae and other animals. In…”
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Modified vaccinia virus Ankara multiplies in rat IEC-6 cells and limited production of mature virions occurs in other mammalian cell lines by Okeke, Malachy Ifeanyi, Nilssen, Oivind, Traavik, Terje

“…1 Department of Microbiology and Virology, Faculty of Medicine, University of Tromsø, N-9037 Tromsø, Norway 2 Department of Medical Genetics, University…”
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