Search Results - "Okda, Tarek M."

Baicalin; a promising chemopreventive agent, enhances the antitumor effect of 5-FU against breast cancer and inhibits tumor growth and angiogenesis in Ehrlich solid tumor by Shehatta, Nisreen H., Okda, Tarek M., Omran, Gamal A., Abd-Alhaseeb, Mohammad M.

“…Despite considerable advances in cancer treatment, chemotherapy remains a cornerstone in breast cancer therapy. Therefore, reducing chemoresistance and adverse…”
Get full text

Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma by Elsayed, Mahmoud, Okda, Tarek, Atwa, Gamal, Omran, Gamal, Abd Elbaky, Atef, Ramadan, Abd

“…Luteolin (LUT) is a natural flavonoid with low oral bioavailability with restricted clinical applications due to its low solubility. LUT shows significant…”
Get full text

Design and Optimization of Sesamol Nanosuspensions to Potentiate the Anti-Tumor Activity of Epirubicin against Ehrlich Solid Carcinoma-Bearing Mice by Elzanaty, Kholoud A, Omran, Gamal A, Elmahallawy, Ehab Kotb, Albrakati, Ashraf, Saleh, Ayman A, Dahran, Naief, Alhegaili, Alaa S, Salahuddin, Ahmad, Abd-El-Azim, Heba, Noreldin, Ahmed, Okda, Tarek M

“…There is a growing interest in discovering natural sources of anti-cancer drugs. Sesamol (SES) is a phenolic compound with antitumor effects. The present study…”
Get full text

Phytic acid potentiates oxaliplatin effects in colorectal cancer induced by 1,2-DMH: the role of miR-224 and miR-200a by Okda, Tarek M, Katry, Mohamed A, Ragab, Noha M, Shalkami, Abdel-Gawad S

“…The third most frequently diagnosed cancer and one of the highest causes of tumour deaths worldwide is colorectal cancer (CRC). The main objective of this…”
Get full text

Quercetin potentiates 5-fluorouracil effects in human colon cancer cells through targeting the Wnt/β-catenin signalling pathway: the role of miR-27a by Terana, Ghada, Abd-Alhaseeb, Mohamed, Omran, Gamal, M. Okda, Tarek

“…Introduction5-fluorouracil (5-FU) is the most widely used chemotherapeutic drug in treating colorectal cancer. However, its toxicity to normal tissues and…”
Get full text

Insights into HPLC-MS/MS Analysis, Antioxidant and Cytotoxic Activity of Astragalus fruticosus against Different Types of Cancer Cell Lines by Dekinash, Mohamed Fayez, Okda, Tarek M., Elmahallawy, Ehab Kotb, El-Fiky, Fathy Kandil, Omran, Gamal Abd El Hay, Svajdlenka, Emil, Dahran, Naief, El-Khadragy, Manal F., Al-Megrin, Wafa A., El Naggar, El Moataz Bellah Ali

“…Plants from the genus Astragalus are gaining attention for their pharmacological importance. However, the information available regarding the HPLC–MS/MS…”
Get full text

A Novel Role of Galectin-3 and Thyroglobulin in Prognosis and Differentiation of Different Stages of Thyroid Cancer and Elucidation of the Potential Contribution of Bcl-2, IL-8 and TNF-α by Okda, Tarek M, Atwa, Gamal M K, Eldehn, Ahmed Fathy, Dahran, Naief, Alsharif, Khalaf F, Elmahallawy, Ehab Kotb

“…Thyroid cancer is among the most prevalent cancers with different types and stages. New markers are required for the prognosis and diagnosis of the disease…”
Get full text

Prognostic Value of Serum Thyroglobulin and Anti-Thyroglobulin Antibody in Thyroid Carcinoma Patients following Thyroidectomy by Zahra, Hashem O., Omran, Gamal A., Gewely, Ahmed G., Eldehn, Ahmed Fathy, Abdo, Walied, Elmahallawy, Ehab Kotb, Okda, Tarek M.

“…Well-differentiated thyroid cancer (WDTC) is a malignant head and neck tumor with a very high incidence. Thyroidectomized WDTC patients have been referred to…”
Get full text

Ameliorative effect of licorice extract against the detrimental effect of glyphosate-based pesticide: Toxicity and health by Elkattan, Ahmed N., El-saadany, Sayad, Azzazy, Mohamed, Okda, Tarek M., Mamdouh, Maha, Ahmed, Osama, El-Far, Ali H., ElKhayat, Manar, Albadrani, Ghadeer M., Al-Ghadi, Muath Q., Abdel-Daim, Mohamed M., El Daous, Hala

“…This study sheds the light on the potential of licorice (Glycyrrhiza glabra) root aqueous extract as a cornerstone for mitigating and detoxifying the residues…”
Get full text

Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer by Badawi, Waleed A., Okda, Tarek M., Abd El Wahab, Shrouk M., Ezz-ElDien, Eman S., AboulWafa, Omaima M.

“…[Display omitted] •Pyrimidine-based morpholine or piperidine conjugates were designed and synthesized.•Several derivatives were endowed with potent…”
Get full text

Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines by Badawi, Waleed A., Samir, Mohamed, Fathy, Hazem M., Okda, Tarek M., Noureldin, Mohamed H., Atwa, Gamal M.K., AboulWafa, Omaima M.

“…•Pyrimidine-based hydrazones were designed and synthesized.•Novel pyrimidine-based hydrazones were screened against two breast adenocarcinoma cells while the…”
Get full text

Chemopreventive and anticancer activities of indomethacin and vitamin D combination on colorectal cancer induced by 1,2-dimethylhydrazine in rats by Okda, Tarek M, Abd-Elghaffar, Sary K, Katary, Mohamed A, Abd-Alhaseeb, Mohammad M

“…Several studies have revealed that the combination of indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), and vitamin D reduces the risk of common…”
Get full text

Insights into HPLC-MS/MS Analysis, Antioxidant and Cytotoxic Activity of IAstragalus fruticosus/I against Different Types of Cancer Cell Lines by Dekinash, Mohamed Fayez, Okda, Tarek M, Elmahallawy, Ehab Kotb, El-Fiky, Fathy Kandil, Omran, Gamal Abd El Hay, Svajdlenka, Emil, Dahran, Naief, El-Khadragy, Manal F, Al-Megrin, Wafa A, El Naggar, El Moataz Bellah Ali

“…Plants from the genus Astragalus are gaining attention for their pharmacological importance. However, the information available regarding the HPLC–MS/MS…”
Get full text