Search Results - "Okda, Tarek M"
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Baicalin; a promising chemopreventive agent, enhances the antitumor effect of 5-FU against breast cancer and inhibits tumor growth and angiogenesis in Ehrlich solid tumor
Published in Biomedicine & pharmacotherapy (01-02-2022)“…Despite considerable advances in cancer treatment, chemotherapy remains a cornerstone in breast cancer therapy. Therefore, reducing chemoresistance and adverse…”
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2
Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma
Published in Pharmaceutics (02-05-2021)“…Luteolin (LUT) is a natural flavonoid with low oral bioavailability with restricted clinical applications due to its low solubility. LUT shows significant…”
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3
Design and Optimization of Sesamol Nanosuspensions to Potentiate the Anti-Tumor Activity of Epirubicin against Ehrlich Solid Carcinoma-Bearing Mice
Published in Pharmaceutics (13-07-2024)“…There is a growing interest in discovering natural sources of anti-cancer drugs. Sesamol (SES) is a phenolic compound with antitumor effects. The present study…”
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Phytic acid potentiates oxaliplatin effects in colorectal cancer induced by 1,2-DMH: the role of miR-224 and miR-200a
Published in Contemporary oncology (Poznan, Poland) (01-01-2021)“…The third most frequently diagnosed cancer and one of the highest causes of tumour deaths worldwide is colorectal cancer (CRC). The main objective of this…”
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5
Quercetin potentiates 5-fluorouracil effects in human colon cancer cells through targeting the Wnt/β-catenin signalling pathway: the role of miR-27a
Published in Contemporary oncology (Poznan, Poland) (01-01-2022)“…Introduction5-fluorouracil (5-FU) is the most widely used chemotherapeutic drug in treating colorectal cancer. However, its toxicity to normal tissues and…”
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6
Insights into HPLC-MS/MS Analysis, Antioxidant and Cytotoxic Activity of Astragalus fruticosus against Different Types of Cancer Cell Lines
Published in Pharmaceuticals (Basel, Switzerland) (14-11-2022)“…Plants from the genus Astragalus are gaining attention for their pharmacological importance. However, the information available regarding the HPLC–MS/MS…”
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7
A Novel Role of Galectin-3 and Thyroglobulin in Prognosis and Differentiation of Different Stages of Thyroid Cancer and Elucidation of the Potential Contribution of Bcl-2, IL-8 and TNF-α
Published in Biomedicines (01-02-2022)“…Thyroid cancer is among the most prevalent cancers with different types and stages. New markers are required for the prognosis and diagnosis of the disease…”
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Prognostic Value of Serum Thyroglobulin and Anti-Thyroglobulin Antibody in Thyroid Carcinoma Patients following Thyroidectomy
Published in Diagnostics (Basel) (10-11-2021)“…Well-differentiated thyroid cancer (WDTC) is a malignant head and neck tumor with a very high incidence. Thyroidectomized WDTC patients have been referred to…”
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9
Ameliorative effect of licorice extract against the detrimental effect of glyphosate-based pesticide: Toxicity and health
Published in Heliyon (30-05-2024)“…This study sheds the light on the potential of licorice (Glycyrrhiza glabra) root aqueous extract as a cornerstone for mitigating and detoxifying the residues…”
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Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer
Published in Bioorganic chemistry (01-12-2024)“…[Display omitted] •Pyrimidine-based morpholine or piperidine conjugates were designed and synthesized.•Several derivatives were endowed with potent…”
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Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines
Published in Bioorganic chemistry (01-09-2023)“…•Pyrimidine-based hydrazones were designed and synthesized.•Novel pyrimidine-based hydrazones were screened against two breast adenocarcinoma cells while the…”
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12
Chemopreventive and anticancer activities of indomethacin and vitamin D combination on colorectal cancer induced by 1,2-dimethylhydrazine in rats
Published in Biomedical reports (01-02-2021)“…Several studies have revealed that the combination of indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), and vitamin D reduces the risk of common…”
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Insights into HPLC-MS/MS Analysis, Antioxidant and Cytotoxic Activity of IAstragalus fruticosus/I against Different Types of Cancer Cell Lines
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2022)“…Plants from the genus Astragalus are gaining attention for their pharmacological importance. However, the information available regarding the HPLC–MS/MS…”
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