Search Results - "Okazaki, Kyoko"
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Effects of Bepridil and Pimozide, Existing Medicines Capable of Blocking T-Type Ca2+ Channels, on Visceral Pain in Mice
Published in Biological & pharmaceutical bulletin (01-03-2021)“…T-Type Ca2+ channels (T-channels), particularly Cav3.2, are now considered as therapeutic targets for treatment of intractable pain including visceral pain…”
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2
Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H2S/Cav3.2 Signaling in Mice
Published in Cells (Basel, Switzerland) (22-07-2020)“…Cystitis-related bladder pain involves RAGE activation by HMGB1, and increased Cav3.2 T-type Ca2+ channel activity by H2S, generated by upregulated…”
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Journal Article -
3
Effects of Bepridil and Pimozide, Existing Medicines Capable of Blocking T-Type Ca2+ Channels, on Visceral Pain in Mice
Published in Biological and Pharmaceutical Bulletin (01-03-2021)“…T-Type Ca2+ channels (T-channels), particularly Cav3.2, are now considered as therapeutic targets for treatment of intractable pain including visceral pain…”
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Journal Article -
4
Successful Improvement of Metabolic Disorders, Including Osteopenia, by a Dopamine Agonist in a Male Patient with Macro-Prolactinoma
Published in The American journal of case reports (13-03-2016)“…Bone metabolic disorders in patients with prolactinoma have not been fully characterized. The case presented herein illustrates potential causal associations…”
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5
Partial Improvement of Anterior Pituitary Deficiency Following Steroid Treatment in a Patient with Neurosarcoidosis Accompanied by Central Diabetes Insipidus
Published in Internal Medicine (01-01-2012)“…A 58-year-old woman was admitted due to visual field abnormalities, thirst, polydipsia, polyuria and fever. T1-weighted magnetic resonance imaging revealed an…”
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Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (−)‐N‐(trans‐4‐isopropylcyclohexane‐carbonyl)‐d‐phenylalanine (A‐4166)
Published in British journal of pharmacology (01-01-1997)“…(−)‐N‐(trans‐4‐isopropylcyclohexanecarbonyl)‐d‐phenylalanine (A‐4166), a novel oral hypoglycaemic agent is a non‐sulphonylurea insulin secretagogue. We…”
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Advanced Glycation End Products (AGEs), but not High Glucose, Inhibit the Osteoblastic Differentiation of Mouse Stromal ST2 Cells Through the Suppression of Osterix Expression, and Inhibit Cell Growth and Increasing Cell Apoptosis
Published in Calcified tissue international (01-10-2012)“…Diabetes mellitus is known to be associated with osteoporotic fractures through a decrease in osteoblastic bone formation rather than an increase in…”
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Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion
Published in Endocrinology (Philadelphia) (01-07-2014)“…In diabetic patients, advanced glycation end products (AGEs) cause bone fragility because of deterioration of bone quality. We previously showed that AGEs…”
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Effects of Bepridil and Pimozide, Existing Medicines Capable of Blocking T-Type Ca 2+ Channels, on Visceral Pain in Mice
Published in Biological & pharmaceutical bulletin (2021)“…T-Type Ca channels (T-channels), particularly Ca 3.2, are now considered as therapeutic targets for treatment of intractable pain including visceral pain…”
Get full text
Journal Article -
10
Mixed Corticomedullary Tumors of the Adrenal Gland Harboring Both Medullary and Cortical Properties
Published in Journal of the Endocrine Society (03-05-2021)“…Adrenal cortex and medulla are derived from mesoderm and ectoderm, respectively. Mixed corticomedullary tumors (MCMTs), comprising an intimately admixed…”
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11
The ability of a new hypoglycaemic agent, A‐4166, compared to sulphonylureas, to increase cytosolic Ca 2+ in pancreatic β‐cells under metabolic inhibition
Published in British journal of pharmacology (17-02-2009)“…N ‐( trans ‐4‐isopropylcyclohexanecarbonyl)‐ d ‐phenylalanine (A‐4166) is a new non‐sulphonylurea oral hypoglycaemic agent which stimulates insulin release by…”
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12
SUN-555 Clinical Outcomes of Thyroid Storm at Kurashiki Central Hospital: Effectiveness of Clinical Criteria and Severity Scores
Published in Journal of the Endocrine Society (30-04-2019)“…BACKGROUND: Thyroid storm (TS) is a life-threatening condition requiring emergency treatment. The reported mortality of TS is 10-20%, but there have not been…”
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Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream [H.sub.2]S/[Ca.sub.v]3.2 Signaling in Mice
Published in Cells (Basel, Switzerland) (01-08-2020)“…Cystitis-related bladder pain involves RAGE activation by HMGB1, and increased [Ca.sub.v]3.2 T-type [Ca.sup.2+] channel activity by [H.sub.2]S, generated by…”
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Journal Article -
15
Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H 2 S/Ca v 3.2 Signaling in Mice
Published in Cells (Basel, Switzerland) (22-07-2020)“…Cystitis-related bladder pain involves RAGE activation by HMGB1, and increased Ca 3.2 T-type Ca channel activity by H S, generated by upregulated…”
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Journal Article -
16
Effect of a New Hypoglycemic Agent, A-4166 [(-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine], on Postprandial Blood Glucose Excursion : Comparison with Voglibose and Glibenclamide
Published in Biological & pharmaceutical bulletin (01-04-1997)“…(-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166) is a new nonsulfonylurea hypoglycemic agent that lowers blood glucose by stimulating…”
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Journal Article -
17
The ability of a new hypoglycaemic agent, A‐4166, compared to sulphonylureas, to increase cytosolic Ca2+ in pancreatic β‐cells under metabolic inhibition
Published in British journal of pharmacology (01-04-1997)“…N‐(trans‐4‐isopropylcyclohexanecarbonyl)‐d‐phenylalanine (A‐4166) is a new non‐sulphonylurea oral hypoglycaemic agent which stimulates insulin release by…”
Get full text
Journal Article -
18
BACTERIOLOGICAL STUDIES ON CARFECILLIN, A NEW ORAL CARBENICILLIN
Published in CHEMOTHERAPY (1975)“…1. Antibacterial spectrum of carfecillin is the same as that of CBPC and I-CBPC, and its antibacterial activity is almost similar to that of CBPC, while it is…”
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BACTERIOLOGICAL STUDIES ON CARBENICILLIN INDANYL SODIUM, A NEW ORAL SYNTHETIC PENICILLIN
Published in CHEMOTHERAPY (1975)“…A bacteriological evaluation was performed on carbenicillin indanyl sodium (I-CBPC) using carbenicillin (CBPC) as a control and the following results were…”
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20
Effect of a New Hypoglycemic Agent, A-4166 [(-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine], on Postprandial Blood Glucose Excursion
Published in Biological & pharmaceutical bulletin (01-04-1997)“…(-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166) is a new nonsulfonylurea hypoglycemic agent that lowers blood glucose by stimulating…”
Get full text
Journal Article