Search Results - "Okawa, Yumiko"
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Depolarization after resonance energy transfer (DARET): A sensitive fluorescence-based assay for botulinum neurotoxin protease activity
Published in Analytical biochemistry (01-06-2011)“…The DARET (depolarization after resonance energy transfer) assay is a coupled Förster resonance energy transfer (FRET)–fluorescence polarization assay for…”
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Integrities of A/B and C domains of RXR are required for rexinoid-induced caspase activations and apoptosis
Published in The Journal of steroid biochemistry and molecular biology (01-11-2008)“…Here we have delineated regions of the retinoid X receptor α (RXRα) that are required for rexinoid (RXR agonist)-induced growth inhibition and apoptosis…”
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Casein Kinase 1α Interacts with Retinoid X Receptor and Interferes with Agonist-induced Apoptosis
Published in The Journal of biological chemistry (16-07-2004)Get full text
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A retinoid-related molecule that does not bind to classical retinoid receptors potently induces apoptosis in human prostate cancer cells through rapid caspase activation
Published in Cancer research (Chicago, Ill.) (01-05-2004)“…Synthetic retinoid-related molecules, such as N-(4-hydroxyphenyl)retinamide (fenretinide) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid…”
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DARET assays of BoNT proteolytic activity with a fully recombinant substrate
Published in Toxicon (Oxford) (01-06-2008)“…The DARET (Depolarization After Resonance Energy Transfer) assay is a homogenous, coupled FRET-fluorescence polarization (FRET-FP) assay for BoNT/A or /E…”
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Fully active recombinant Bont/E purified from E. coli in high yield
Published in Toxicon (Oxford) (01-06-2008)“…Both rHis6-BoNT/E and rBoNT/E-His6 were produced from a codon optimized gene within Escherichia coli. Similar to native BoNT/E isolated from Clostridium…”
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Casein Kinase 1α Interacts with Retinoid X Receptor and Interferes with Agonist-induced Apoptosis
Published in The Journal of biological chemistry (16-07-2004)“…Agonists of retinoid X receptors (RXRs), which include the natural 9- cis -retinoic acid and synthetic analogs, are potent inducers of growth arrest and…”
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Casein kinase 1alpha interacts with retinoid X receptor and interferes with agonist-induced apoptosis
Published in The Journal of biological chemistry (16-07-2004)“…Agonists of retinoid X receptors (RXRs), which include the natural 9-cis-retinoic acid and synthetic analogs, are potent inducers of growth arrest and…”
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