Search Results - "Okamoto, U"

Structure-inhibitory activity relationship of plasmin and plasma kallikrein inhibitors by Tsuda, Y, Tada, M, Wanaka, K, Okamoto, U, Hijikata-Okunomiya, A, Okamoto, S, Okad, Y

“…Based on the structure of Tra-Tyr(O-Pic)-octylamide, a portion of the octylamine was replaced with moieties bearing hydrophobic, basic or acidic groups…”
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Human leukocyte elastase-like proteinase purified by affinity chromatography with Suc-L-Tyr-D-Leu-D-Val-pNA, and its identification with human spleen fibrinolytic proteinase by Nagamatsu, Y, Okamoto, U, Tsuda, Y, Okada, Y

“…Elastase-like proteinase ( ELP ) extracted with 2 M NaClO4 from human leukocytes was purified by a new affinity chromatography technique with…”
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Proactivator-activator system in human plasma fibrinolysis: studies on the synthetic fibrinolytic system composed of functionally pure fibrinogen, plasminogen and proactivator, separated from human plasma by Okamoto, U

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Demonstration of two types of plasminogen activators in human milk by SDS-PAGE copolymerizing fibrinogen and plasminogen: different variations of the activators in pueriperium by Horie, N, Okamoto, U, Wijngaards, G

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Variation in activities of non-plasmin fibrinolytic proteinase and plasminogen-activator in the lung and spleen induced by bacterial endotoxin in rats with special reference to the effects of MD-805 by Okamoto, U, Nagamatsu, Y, Horie, N, Yamamoto, J, Sasaki, K

“…The behavior of direct fibrinolytic (non-plasmin) proteinase activity and plasminogen-activator activity in the lung and spleen was investigated in rats after…”
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Clearance of modified plasminogen produced in the circulation after strenuous exercise by Yamamoto, J, Morita, S, Okamoto, U

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A new polypeptide substrate, Suc-Tyr-Leu-Val-pNA, specific for spleen fibrinolytic proteinase (SFP) by Okamoto, U, Nagamatsu, Y, Tsuda, Y, Okada, Y

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New modified activated partial thromboplastin time and prothrombin time methods using a synthetic chromogenic substrate in combination with diazotization by Yamamoto, J, Asada, N, Miyatake, Y, Masuya, M, Yamashita, T, Okamoto, U

“…A chromogenic substrate, H-D-Phe-Pip-Arg-pNA (S-2238) is a highly specific substrate to thrombin and releases p-nitroaniline (pNA) by the action of thrombin…”
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Highly selective synthetic inhibitors with regard to plasma-kallikrein activities by Okamoto, S, Okamoto, U, Wanaka, K, Hijikata-Okunomiya, A, Bohgaki, M, Naito, T, Horie, N, Okada, Y

“…The synthetic inhibitors of plasma kallikrein (PK) were found, which are called PKSI-1007, PKSI-0180 and PKSI-0527 in our laboratories. (1) The inhibitors…”
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Human spleen insoluble fibrinolytic proteinase acting at neutral pH: its partial purification and characterization by Okamoto, U, Nagamatsu, Y, Amemiya, T

“…An insoluble fibrinolytic enzyme with a molecular weight of approximately 30,000, was purified from the human spleen. A single protein band possessing…”
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Activation system of fibrinolysis (author's transl) by Okamoto, U

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Fibrinolytic and amidolytic activities of elastase-and chymotrypsin-like proteases in spleen and leukocytes of some mammals by Nagamatsu, Y, Okamoto, U, Yamamoto, J, Tsuda, Y, Okada, Y

“…Nonplasmin-mediated fibrinolytic activities were extracted with 2 M NaCIO4 from the spleen and leukocytes of nine species of mammals. The amidolytic and…”
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Plasminogen-activator in human early milk: its partial purification and characterization by Okamoto, U, Horie, N, Nagamatsu, Y, Yamamoto, J I

“…Milk plasminogen-activator was partially purified from human transitional milk collected at about 10 days after delivery, by a five-step procedure involving…”
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A partially degraded form of human plasminogen in circulating blood by Yamamoto, J, Okamoto, U, Kojima, S, Morita, S, Fujii, K

“…A method for separate measurement of the amounts of the native form and partially degraded form of plasminogen and plasmin in human circulating blood was…”
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The estimation method for plasminogen content using fibrin plate with urokinase (author's transl) by Horie, N, Okamoto, U

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ON THE DISAPPEARANCE OF THE TISSUE PLASMINOGEN ACTIVATOR ACTIVITY IN KIDNEY PRODUCED BY MITOMYCIN C ADMINISTRATION TO RABBITS by OKAMOTO, U, TAKADA, Y

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Fibrinolytic activity of lung and spleen extracts observed in conventional but not in germ-free rats by Okamoto, U, Yamamoto, J I, Nagamatsu, Y, Horie, N

“…Protease-like activity which split plasminogen-free fibrin was demonstrated in 2 M KSCN extracts of the lung and spleen of conventional rats. The activity was…”
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Enzyme-controlling medicines: introduction by Okamoto, S, Hijikata-Okunomiya, A, Wanaka, K, Okada, Y, Okamoto, U

“…A short history of the research work of S. Okamoto and co-workers, for the previous 50 years, is briefly described. In the 1950s, when the physiologic role of…”
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Proceedings: A smaller molecule SK-reactive protein (plasminogen-proactivator) derived from the macromolecule of human plasma fraction I by Okamoto, U, Yamamoto, J

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A method for separation of plasminogen from bovine plasma fraction. I. With reference to some properties of the plasminogen by Okamoto, U, Matumoto, M

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