Search Results - "Okai, Shinsaku"

Integrin CD11b provides a new marker of pre-germinal center IgA+ B cells in murine Peyer’s patches by Gao, Peng, Adachi, Takahiro, Okai, Shinsaku, Morita, Naoki, Kitamura, Daisuke, Shinkura, Reiko

“…Abstract Activated B cells can enter germinal centers (GCs) for affinity maturation to produce high-affinity antibodies. However, which activated B cells will…”
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High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice by Okai, Shinsaku, Usui, Fumihito, Yokota, Shuhei, Hori-i, Yusaku, Hasegawa, Makoto, Nakamura, Toshinobu, Kurosawa, Manabu, Okada, Seiji, Yamamoto, Kazuya, Nishiyama, Eri, Mori, Hiroshi, Yamada, Takuji, Kurokawa, Ken, Matsumoto, Satoshi, Nanno, Masanobu, Naito, Tomoaki, Watanabe, Yohei, Kato, Tamotsu, Miyauchi, Eiji, Ohno, Hiroshi, Shinkura, Reiko

“…Immunoglobulin A (IgA) is the main antibody isotype secreted into the intestinal lumen. IgA plays a critical role in the defence against pathogens and in the…”
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Decreased Taxon-Specific IgA Response in Relation to the Changes of Gut Microbiota Composition in the Elderly by Sugahara, Hirosuke, Okai, Shinsaku, Odamaki, Toshitaka, Wong, Chyn B, Kato, Kumiko, Mitsuyama, Eri, Xiao, Jin-Zhong, Shinkura, Reiko

“…Gut microbiota is known to change with aging; however, the underlying mechanisms have not been well elucidated. Immunoglobulin A (IgA) is the dominant class of…”
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Hypermutated Intestinal IgA Modulates Intestinal Microbiota towards Symbiosis by SHINKURA, Reiko, OKAI, Shinsaku, USUI, Fumihito

“…Dysbiosis of gut microbiota disrupts intestinal homeostasis and not only causes inflammatory bowel diseases but is also involved in other diseases. Intestinal…”
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腸管IgA抗体による腸内細菌制御のメカニズム by 新藏, 礼子, 岡井, 晋作, 臼井, 文人

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Intestinal IgA as a modulator of the gut microbiota by Okai, Shinsaku, Usui, Fumihito, Ohta, Misa, Mori, Hiroshi, Kurokawa, Ken, Matsumoto, Satoshi, Kato, Tamotsu, Miyauchi, Eiji, Ohno, Hiroshi, Shinkura, Reiko

“…Accumulating evidence suggests that dysbiosis plays a role in the pathogenesis of intestinal diseases including inflammatory bowel disease (IBD) as well as…”
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A novel germline mutation in a patient with nevoid basal cell carcinoma syndrome showing cystic lesion in the lung by Miyata, Ryo, Kurosawa, Manabu, Sato, Masaaki, Kono, Tomoya, Takubo, Yasutaka, Okai, Shinsaku, Yamada, Keisuke, Shinkura, Reiko, Date, Hiroshi, Matsuda, Fumihiko

“…Nevoid basal cell carcinoma syndrome (NBCCS) manifests multiple defects involving the skin, endocrine and nervous systems, eyes and bones. Mutations in the…”
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