Search Results - "Okafor, C. C."
-
1
Science and technology of ammonia combustion
Published in Proceedings of the Combustion Institute (2019)“…This paper focuses on the potential use of ammonia as a carbon-free fuel, and covers recent advances in the development of ammonia combustion technology and…”
Get full text
Journal Article -
2
Bile acids and the gut microbiota: metabolic interactions and impacts on disease
Published in Nature reviews. Microbiology (01-04-2023)“…Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human…”
Get full text
Journal Article -
3
Experimental and numerical study of the laminar burning velocity of CH4–NH3–air premixed flames
Published in Combustion and flame (01-01-2018)“…With the renewed interest in ammonia as a carbon-neutral fuel, mixtures of ammonia and methane are also being considered as fuel. In order to develop gas…”
Get full text
Journal Article -
4
Emission characteristics of turbulent non-premixed ammonia/air and methane/air swirl flames through a rich-lean combustor under various wall thermal boundary conditions at high pressure
Published in Combustion and flame (01-12-2019)“…This study is dedicated to understanding the combustion and emission characteristics of turbulent non-premixed ammonia (NH3)/air and methane (CH4)/air swirl…”
Get full text
Journal Article -
5
Towards the development of an efficient low-NOx ammonia combustor for a micro gas turbine
Published in Proceedings of the Combustion Institute (2019)“…Recent studies have demonstrated stable generation of power from pure ammonia combustion in a micro gas turbine (MGT) with a high combustion efficiency, thus…”
Get full text
Journal Article -
6
How nuclear receptors transition between active and inactive forms: An energetic perspective
Published in The Journal of chemical physics (21-03-2024)“…Nuclear receptors regulate transcriptional programs in response to the binding of natural and synthetic ligands. These ligands modulate the receptor by…”
Get more information
Journal Article -
7
Correlation Between the Clinical Diagnosis and Sonographic Diagnosis in Women with First-Trimester Vaginal Bleeding
Published in Nigerian journal of clinical practice (01-02-2024)“…Vaginal bleeding is the most common cause of presentation at the emergency department in the first trimester. Clinical presentation helps determine the likely…”
Get full text
Journal Article -
8
Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites
Published in PLoS pathogens (01-10-2022)“…Plasmodium parasites are reliant on the Apicomplexan AP2 (ApiAP2) transcription factor family to regulate gene expression programs. AP2 DNA binding domains…”
Get full text
Journal Article -
9
Illuminating ligand-induced dynamics in nuclear receptors through MD simulations
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-06-2024)“…Nuclear receptors (NRs) regulate gene expression in critical physiological processes, with their functionality finely tuned by ligand-induced conformational…”
Get full text
Journal Article -
10
Nuclear Receptor Interdomain Communication is Mediated by the Hinge with Ligand Specificity
Published in Journal of molecular biology (15-11-2024)“…[Display omitted] •In this work, we seek to understand interdomain communication in a nuclear receptor.•Simulations reveal ligand-induced interdomain contact…”
Get full text
Journal Article -
11
Structure and assembly of the diiron cofactor in the heme-oxygenase–like domain of the N-nitrosourea–producing enzyme SznF
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2021)“…In biosynthesis of the pancreatic cancer drug streptozotocin, the tridomain nonheme-iron oxygenase SznF hydroxylates N δ and N ω′ of N ω-methyl-L-arginine…”
Get full text
Journal Article -
12
Identification of an Evolutionarily Conserved Allosteric Network in Steroid Receptors
Published in Journal of chemical information and modeling (23-01-2023)“…Allosteric pathways in proteins describe networks comprising amino acid residues which may facilitate the propagation of signals between distant sites. Through…”
Get full text
Journal Article -
13
Interactions governing transcriptional activity of nuclear receptors
Published in Biochemical Society transactions (16-12-2022)“…The key players in transcriptional regulation are transcription factors (TFs), proteins that bind specific DNA sequences. Several mechanisms exist to turn TFs…”
Get more information
Journal Article -
14
Effects of hydrogen concentration on premixed laminar flames of hydrogen–methane–air
Published in International journal of hydrogen energy (04-02-2014)“…The unstretched laminar burning velocities and Markstein numbers of spherically propagating hydrogen–methane–air flames were studied at a mixture pressure of…”
Get full text
Journal Article -
15
Comparative evaluation of biogas production from Poultry droppings, Cow dung and Lemon grass
Published in Bioresource technology (01-04-2014)“…The study explored the production of biogas from Lemon grass, Cow dung and Poultry droppings. The three substrates were pre-fermented according to standard…”
Get full text
Journal Article -
16
Ancestral sequence reconstruction for evolutionary characterization of proteins
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-01-2022)Get full text
Journal Article -
17
The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits
Published in Protein science (01-10-2023)“…Nuclear receptors (NRs) are transcription factors that regulate essential biological processes in response to cognate ligands. An important part of NR function…”
Get full text
Journal Article -
18
Analysis of bacterial communities of three cassava‐based traditionally fermented Nigerian foods (abacha, fufu and garri)
Published in Letters in applied microbiology (01-03-2022)“…Globally, cassava is an important food crop that contributes significantly to food security. In Nigeria, cassava can be traditionally processed into abacha…”
Get full text
Journal Article -
19
The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor
Published in Scientific reports (10-09-2018)“…The glucocorticoid receptor (GR) is a steroid hormone receptor of the nuclear receptor family that regulates gene expression in response to glucocorticoid…”
Get full text
Journal Article -
20
Associations between meniscal tears and various degrees of osteoarthritis among dogs undergoing TPLO for cranial cruciate ligament rupture
Published in BMC research notes (13-03-2023)“…The aim of this study was to evaluate the association between meniscal lesions and severity of osteoarthritis (OA) among dogs that underwent Tibial Plateau…”
Get full text
Journal Article