Search Results - "Okada , Y"

Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system by Akita, T, Okada, Y

“…Highlights • The VSOR anion channel is expressed in all types of cells in the CNS. • The channel produces a major anion flux during cell volume regulation. •…”
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From the era of genome analysis to the era of genomic drug discovery: a pioneering example of rheumatoid arthritis by Okada, Y.

“…Although we have obtained comprehensive catalogs of genetic risk loci that are linked to human diseases, little is known regarding how to devise a systematic…”
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Blue Light‐Promoted N−H Insertion of Carbazoles, Pyrazoles and 1,2,3‐Triazoles into Aryldiazoacetates by Stivanin, Mateus L., Fernandes, Alessandra A. G., Silva, Amanda F., Okada, Celso Y., Jurberg, Igor D.

“…Blue light irradiation of aryldiazoacetates leads to the formation of free carbenes, which can react with carbazoles, pyrazoles and 1,2,3‐triazoles to afford…”
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Unveiling the Formation of the Massive DR21 Ridge by Bonne, L., Bontemps, S., Schneider, N., Simon, R., Clarke, S. D., Csengeri, T., Chambers, E., Graf, U., Jackson, J. M., Klein, R., Okada, Y., Tielens, A. G. G. M., Tiwari, M.

“…Abstract We present new 13 CO (1−0), C 18 O (1−0), HCO + (1−0), and H 13 CO + (1−0) maps from the IRAM 30 m telescope and a spectrally resolved [C ii ] 158 μ m…”
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Visible-Light-Mediated Strategies to Assemble Alkyl 2‑Carboxylate-2,3,3-Trisubstituted β‑Lactams and 5‑Alkoxy-2,2,4-Trisubstituted Furan-3(2H)-ones Using Aryldiazoacetates and Aryldiazoketones by Munaretto, Laiéli S, dos Santos, Caio Y, Gallo, Rafael D. C, Okada, Celso Y, Deflon, Victor M, Jurberg, Igor D

“…Two new visible-light-mediated strategies are described starting from aryldiazoacetates. The first approach describes their reaction with azides to afford the…”
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Precipitation Changes in a Climate With 2‐K Surface Warming From Large Ensemble Simulations Using 60‐km Global and 20‐km Regional Atmospheric Models by Fujita, M., Mizuta, R., Ishii, M., Endo, H., Sato, T., Okada, Y., Kawazoe, S., Sugimoto, S., Ishihara, K., Watanabe, S.

“…A near‐future, 2‐K warming climate simulation comprising over 3,000 years of ensemble simulations was performed using 60‐km global and 20‐km regional…”
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Photoabsorption improvement in multi-stacked InGaAs/GaAs quantum dot solar cell with a light scattering rear texture by Shoji, Y., Watanabe, K., Okada, Y.

“…A 50-layer stacked InGaAs/GaAs quantum dot solar cell (QDSC) grown on GaAs (100) with a self-organized texture formed on its backside has been fabricated in…”
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Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways by Xin, B, Yamamoto, M, Fujii, K, Ooshio, T, Chen, X, Okada, Y, Watanabe, K, Miyokawa, N, Furukawa, H, Nishikawa, Y

“…MYC activation at modest levels has been frequently found in hepatocellular carcinoma. However, its significance in hepatocarcinogenesis has remained obscure…”
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Safety of tooth extraction in patients receiving direct oral anticoagulant treatment versus warfarin: a prospective observation study by Yoshikawa, H., Yoshida, M., Yasaka, M., Yoshida, H., Murasato, Y., Fukunaga, D., Shintani, A., Okada, Y.

“…The aim of this study was to compare the safety of tooth extraction in patients receiving direct oral anticoagulants (DOACs) or warfarin without cessation of…”
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Cyclin-Dependent Kinase-9 Is a Therapeutic Target in MYC-Expressing Diffuse Large B-Cell Lymphoma by Hashiguchi, Taylor, Bruss, Nur, Best, Scott, Lam, Vi, Danilova, Olga, Paiva, Cody J, Wolf, Joelle, Gilbert, Erin W, Okada, Craig Y, Kaur, Prabhjot, Drew, Lisa, Cidado, Justin, Hurlin, Peter, Danilov, Alexey V

“…Deregulation of the MYC transcription factor is a key driver in lymphomagenesis. MYC induces global changes in gene expression that contribute to cell growth,…”
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Stellar Feedback on the Earliest Stage of Massive Star Formation by Nayak, O., Meixner, M., Okada, Y., Lee, M. Y., Chevance, M., Buchbender, C., Fukui, Y., Onishi, T., Parikka, A., Stutzki, J.

“…Abstract We report SOFIA/GREAT observations of high- J CO lines and [C ii ] observations of the super star cluster candidate H72.97-69.39 in the Large…”
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Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor by Okada, Y

“…The maintenance of a constant volume in the face of extracellular and intracellular osmotic perturbation is essential for the normal function and survival of…”
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Development and validation of a model to predict the need for emergency front‐of‐neck airway procedures in trauma patients by Okada, Y., Hashimoto, K., Ishii, W., Iiduka, R., Koike, K.

“…Summary The present study aimed to develop and validate a model for predicting the need for emergency front‐of neck airway (eFONA) procedures among trauma…”
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A multi‐emitter fitting algorithm for potential live cell super‐resolution imaging over a wide range of molecular densities by TAKESHIMA, T., TAKAHASHI, T., YAMASHITA, J., OKADA, Y., WATANABE, S.

“…Summary Multi‐emitter fitting algorithms have been developed to improve the temporal resolution of single‐molecule switching nanoscopy, but the molecular…”
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Analysis of induced pluripotent stem cells carrying 22q11.2 deletion by Toyoshima, M, Akamatsu, W, Okada, Y, Ohnishi, T, Balan, S, Hisano, Y, Iwayama, Y, Toyota, T, Matsumoto, T, Itasaka, N, Sugiyama, S, Tanaka, M, Yano, M, Dean, B, Okano, H, Yoshikawa, T

“…Given the complexity and heterogeneity of the genomic architecture underlying schizophrenia, molecular analyses of these patients with defined and large…”
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Creatinine to Cystatin C Ratio as a Marker of Bone Property in Older Adults: The J-Shipp Study by Tabara, Yasuharu, Kohara, K., Okada, Y., Ohyagi, Y., Igase, M.

“…Objectives To clarify whether serum creatinine to cystatin C ratio (CCR), a marker of muscle mass and muscle function may be used as a simple marker of bone…”
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Toward noninvasive monitoring of ongoing electrical activity of human uterus and fetal heart and brain by Lew, S., Hämäläinen, M.S., Okada, Y.

“…•Evaluated a fetal-maternal scanner for monitoring electrical maternal and fetal organ activity.•The simulated scanner can monitor the uterine and fetal heart…”
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Donor cell leukemia arising from preleukemic clones with a novel germline DDX41 mutation after allogenic hematopoietic stem cell transplantation by Kobayashi, S, Kobayashi, A, Osawa, Y, Nagao, S, Takano, K, Okada, Y, Tachi, N, Teramoto, M, Kawamura, T, Horiuchi, T, Kato, S, Maekawa, T, Yamamura, T, Watanabe, J, Harada, Y, Harada, H, Sato, K, Kimura, F

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Reduction of hyaluronan and increased expression of HYBID (alias CEMIP and KIAA1199) correlate with clinical symptoms in photoaged skin by Yoshida, H., Nagaoka, A., Komiya, A., Aoki, M., Nakamura, S., Morikawa, T., Ohtsuki, R., Sayo, T., Okada, Y., Takahashi, Y.

“…Summary Background Hyaluronan (HA) metabolism in skin fibroblasts is mediated by HYBID (hyaluronan binding protein involved in hyaluronan depolymerization,…”
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Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes by Yatabe, T, Mochizuki, S, Takizawa, M, Chijiiwa, M, Okada, A, Kimura, T, Fujita, Y, Matsumoto, H, Toyama, Y, Okada, Y

“…Intra-articular injection of hyaluronan (HA) has been suggested to have a disease-modifying effect in osteoarthritis, but little is known about the possible…”
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