Search Results - "Okada, Mai"

Morphokinetic analysis of pronuclei using time-lapse cinematography in bovine zygotes by Suzuki, Ryosuke, Okada, Mai, Nagai, Hiroki, Kobayashi, Junichi, Sugimura, Satoshi

“…The morphokinetics of pronuclei (PN) are considered crucial factors affecting embryogenesis in mammals. Whereas, since bovine zygotes contain a large number of…”
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A new subfamily of polyphosphate kinase 2 (class III PPK2) catalyzes both nucleoside monophosphate phosphorylation and nucleoside diphosphate phosphorylation by Motomura, Kei, Hirota, Ryuichi, Okada, Mai, Ikeda, Takeshi, Ishida, Takenori, Kuroda, Akio

“…Inorganic polyphosphate (polyP) is a linear polymer of tens to hundreds of phosphate (Pi) residues linked by "high-energy" phosphoanhydride bonds as in ATP…”
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Abnormal cleavage is involved in the self-correction of bovine preimplantation embryos by Nagai, Hiroki, Okada, Mai, Nagai, Yoko, Sakuraba, Yoshiyuki, Okae, Hiroaki, Suzuki, Ryosuke, Sugimura, Satoshi

“…Chromosome instability leading to aneuploidy during early cleavage is well known in humans and cattle. Partial compaction (PC), which occurs only in some…”
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Direct cleavage during the first mitosis is a sign of abnormal fertilization in cattle by Suzuki, Ryosuke, Yao, Tatsuma, Okada, Mai, Nagai, Hiroki, Khurchabilig, Atchalalt, Kobayashi, Junichi, Yamagata, Kazuo, Sugimura, Satoshi

“…Direct cleavage, a type of abnormal cleavage in which one zygote divides into three or more blastomeres, has been reported in mammals. The incidence of direct…”
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Build-up functionalization of anti-EGFR × anti-CD3 bispecific diabodies by integrating high-affinity mutants and functional molecular formats by Asano, Ryutaro, Hosokawa, Katsuhiro, Taki, Shintaro, Konno, Shota, Shimomura, Ippei, Ogata, Hiromi, Okada, Mai, Arai, Kyoko, Onitsuka, Masayoshi, Omasa, Takeshi, Nakanishi, Takeshi, Umetsu, Mitsuo, Kumagai, Izumi

“…Designing non-natural antibody formats is a practical method for developing highly functional next-generation antibody drugs, particularly for improving the…”
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Time-course colony tracking analysis for evaluating induced pluripotent stem cell culture processes by Yoshida, Kei, Okada, Mika, Nagasaka, Risako, Sasaki, Hiroto, Okada, Mai, Kanie, Kei, Kato, Ryuji

“…Increasing the yield and maintaining a high quality of induced pluripotent stem cells (iPSCs) is necessary for manufacturing iPSCs at the industrial scale…”
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Label-free morphology-based prediction of multiple differentiation potentials of human mesenchymal stem cells for early evaluation of intact cells by Sasaki, Hiroto, Takeuchi, Ichiro, Okada, Mai, Sawada, Rumi, Kanie, Kei, Kiyota, Yasujiro, Honda, Hiroyuki, Kato, Ryuji

“…Precise quantification of cellular potential of stem cells, such as human bone marrow-derived mesenchymal stem cells (hBMSCs), is important for achieving…”
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Stereoselective Alkylation of Oxathiazinane N,O-Ketals for the Construction of Aza-Quaternary Carbon Centers by Yakura, Takayuki, Tanaka, Eri, Okada, Mai, Hirosawa, Chiaki, Noda, Narumi, Fujiwara, Tomoya

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Expression analysis of zinc-metabolizing enzymes in the saliva as a new method of evaluating zinc content in the body: two case reports and a review of the literature by Sakata, Ken-Ichiro, Hashimoto, Ayako, Kambe, Taiho, Sato, Jun, Ohga, Noritaka, Yamazaki, Yutaka, Koyachi, Masahide, Tatsuki, Itagaki, Okada, Mai, Taro, Okura, Hikasa, Hiroshi, Kitagawa, Yoshimasa

“…The activity level of alkaline phosphatase, a zinc-requiring enzyme in the serum, is used to indicate zinc nutritional status; however, it does not correlate…”
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Visualization of morphological categories of colonies for monitoring of effect on induced pluripotent stem cell culture status by Nagasaka, Risako, Matsumoto, Megumi, Okada, Mai, Sasaki, Hiroto, Kanie, Kei, Kii, Hiroaki, Uozumi, Takayuki, Kiyota, Yasujiro, Honda, Hiroyuki, Kato, Ryuji

“…From the recent advances, there are growing expectations toward the mass production of induced pluripotent stem cells (iPSCs) for varieties of applications…”
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Impact of the COVID-19 pandemic on patients with mental health problems and the differences among diagnostic categories by Mashima, Yuki, Koizumi, Teruki, Minegishi, Shunta, Miyakoshi, Megumi, Okada, Mai, Ogyu, Kamiyu, Kusudo, Keisuke, Kiyohara, Masataka, Kitada, Shinobu, Koyanagi, Kazuhiro, Suzuki, Hisaomi, Nozaki, Shoko, Oda, Akihiko, Hirai, Shinji, Nakane, Jun, Onaya, Mitsumoto, Oda, Tatsuro, Koreki, Akihiro

“…Background: The coronavirus disease 2019 (COVID-19) pandemic has resulted in a total upending of our daily lives. While anxiety and depression were frequently…”
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In-process evaluation of culture errors using morphology-based image analysis by Imai, Yuta, Yoshida, Kei, Matsumoto, Megumi, Okada, Mai, Kanie, Kei, Shimizu, Kazunori, Honda, Hiroyuki, Kato, Ryuji

“…Advancing industrial-scale manufacture of cells as therapeutic products is an example of the wide applications of regenerative medicine. However, one…”
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Metabolism of steroids by cytochrome P450 2C9 variants by Uno, Tomohide, Nakano, Ryosuke, Kitagawa, Risa, Okada, Mai, Kanamaru, Kengo, Takenaka, Shinji, Uno, Yuichi, Imaishi, Hiromasa

“…CYP2C9 is a human microsomal cytochrome P450c (CYP). Much variation in CYP2C9 levels and activity can be attributed to polymorphisms of this gene. Wild‐type…”
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Gingival and dermal fibroblasts: Their similarities and differences revealed from gene expression by Ebisawa, Katsumi, Kato, Ryuji, Okada, Mai, Sugimura, Tomotaka, Latif, Mazlyzam Abdul, Hori, Yusuke, Narita, Yuji, Ueda, Minoru, Honda, Hiroyuki, Kagami, Hideaki

“…Gene expression profiles in normal human gingival and dermal fibroblasts were investigated using DNA microarrays. Their fundamental characteristics were almost…”
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Domain order of a bispecific diabody dramatically enhances its antitumor activity beyond structural format conversion: the case of the hEx3 diabody by Asano, Ryutaro, Kumagai, Takashi, Nagai, Keisuke, Taki, Shintaro, Shimomura, Ippei, Arai, Kyoko, Ogata, Hiromi, Okada, Mai, Hayasaka, Fumitaka, Sanada, Hideaki, Nakanishi, Takeshi, Karvonen, Teemu, Hayashi, Hiroki, Katayose, Yu, Unno, Michiaki, Kudo, Toshio, Umetsu, Mitsuo, Kumagai, Izumi

“…The domains of bispecific diabodies (BsDbs) can be ordered in four different ways; however, the influence of domain order on the cytotoxicity of BsDbs that…”
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Overproduction of YjbB reduces the level of polyphosphate in Escherichia coli: a hypothetical role of YjbB in phosphate export and polyphosphate accumulation by Motomura, Kei, Hirota, Ryuichi, Ohnaka, Nobuteru, Okada, Mai, Ikeda, Takeshi, Morohoshi, Tomohiro, Ohtake, Hisao, Kuroda, Akio

“…Abstract Intracellular phosphate (Pi) is normally maintained at a fairly constant concentration in Escherichia coli, mainly by Pi transport systems and by the…”
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Rearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokinetics by Asano, Ryutaro, Shimomura, Ippei, Konno, Shota, Ito, Akiko, Masakari, Yosuke, Orimo, Ryota, Taki, Shintaro, Arai, Kyoko, Ogata, Hiromi, Okada, Mai, Furumoto, Shozo, Onitsuka, Masayoshi, Omasa, Takeshi, Hayashi, Hiroki, Katayose, Yu, Unno, Michiaki, Kudo, Toshio, Umetsu, Mitsuo, Kumagai, Izumi

“…One approach to creating more beneficial therapeutic antibodies is to develop bispecific antibodies (bsAbs), particularly IgG-like formats with tetravalency,…”
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Determination of phenolic acids in fruit juices by isocratic column liquid chromatography by Amakura, Yoshiaki, Okada, Mai, Tsuji, Sumiko, Tonogai, Yasuhide

“…A simple and rapid analytical method of five phenolic acids, gallic, chlorogenic, caffeic, ellagic and ferulic acid, which are naturally occurring bioactives,…”
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The interaction of antiemetic dose of droperidol with propofol on QT interval during anesthetic induction by Toyoda, Tomomi, Terao, Yoshiaki, Oji, Makito, Okada, Mai, Fukusaki, Makoto, Sumikawa, Koji

“…Purpose We investigated the effect of low-dose droperidol on heart rate-corrected QT (QTc) interval and interaction with propofol. Methods Seventy-two patients…”
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Statistical Characterization of Nonbonded S···O Interactions in Proteins by Iwaoka, Michio, Takemoto, Shinya, Okada, Mai, Tomoda, Shuji

“…Weak nonbonded S···O interactions were characterized as stabilizing forces of protein structures based on the database analysis of selected heterogeneous…”
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