Search Results - "Oka, Adwait"

γ-secretase inhibitors augment efficacy of BCMA-targeting bispecific antibodies against multiple myeloma cells without impairing T-cell activation and differentiation by Chen, Hailin, Yu, Tengteng, Lin, Liang, Xing, Lijie, Cho, Shih-Feng, Wen, Kenneth, Aardalen, Kimberly, Oka, Adwait, Lam, Joni, Daley, Mike, Lu, Haihui, Munshi, Nikhil, Anderson, Kenneth C., Tai, Yu-Tzu

“…We here defined the impacts of γ-secretase inhibitors (GSIs) on T-cell-dependent BCMA-specific multiple myeloma (MM) cell lysis and immunomodulatory effects…”
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Combination wt-p53 and MicroRNA-125b Transfection in a Genetically Engineered Lung Cancer Model Using Dual CD44/EGFR-targeting Nanoparticles by Talekar, Meghna, Trivedi, Malav, Shah, Parin, Ouyang, Qijun, Oka, Adwait, Gandham, Srujan, Amiji, Mansoor M

“…Mutations in KRAS and p53 signaling pathways contribute to loss of responsiveness to current therapies and a decreased survival in lung cancer. In this study,…”
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Γ-Secretase Inhibitors Enhance the Potency of BCMA-Targeting T Cell Engagers Against Multiple Myeloma Cells without Adverse Impact on T-Cell Activation and Differentiation by Chen, Hailin, Yu, Tengteng, Lin, Liang, Xing, Lijie, Cho, Shih-Feng, Wen, Kenneth, Aardalen, Kimberly, Daley, Mike, Lu, Haihui, Oka, Adwait, Lam, Joni, Munshi, Nikhil C, Anderson, Kenneth C., Tai, Yu-Tzu

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PIT565, a First-in-Class Anti-CD19, Anti-CD3, Anti-CD2 Trispecific Antibody for the Treatment of B Cell Malignancies by Lu, Haihui, Oka, Adwait, Coulson, Michelle, Polli, Joseph Ryan, Aardalen, Kimberly, Ramones, Melissa, Walker, Dana B, Carrion, Ana, Alexander, Dylan, Klopfenstein, Matthieu, Akiyama, Masaki, Rucci, Francesca, Granda, Brian, Pastore, Alessandro

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Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody by Raab, Marc S., Cohen, Yael C., Schjesvold, Fredrik, Aardalen, Kimberly, Oka, Adwait, Spencer, Andrew, Wermke, Martin, Souza, Anita D., Kaufman, Jonathan L., Cafro, Anna Maria, Ocio, Enrique M., Doki, Noriko, Henson, Kristin, Trabucco, Gina, Carrion, Ana, Bender, Florent C., Juif, Pierre-Eric, Fessehatsion, Adonai, Fan, Liqiong, Stonehouse, Jeffrey P., Blankenship, John W., Granda, Brian, De Vita, Serena, Lu, Haihui

“…B-cell maturation antigen (BCMA) is an ideal target in multiple myeloma (MM) due to highly specific expression in malignant plasma cells. BCMA-directed…”
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OAB-009: γ-secretase inhibitors augment efficacy of BCMA-targeting T cell engagers against multiple myeloma cells without impairing T cell effector function by Tai, Yu-Tzu, Chen, Hailin, Yu, Tengteng, Lin, Liang, Xing, Lijie, Cho, Shih-Feng, Wen, Kenneth, Aardalen, Kimberly, Oka, Adwait, Lam, Joni, Daley, Mike, Lu, Haihui, Munshi, Nikhil, Anderson, Kenneth

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Targeted siRNA Delivery Strategy with Water-in-Oil-in-Water Multiple Emulsion for Modulation of Tumor-Associated Macrophage Polarity in Immunotherapy of Cancer by Oka, Adwait

“…Despite greater understanding of the molecular mechanisms and the resulting targeted therapeutic strategies, the mortality rate associated with cancer has not…”
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Targeted siRNA Delivery Strategy with Water-in-Oil-in-Water Multiple Emulsion for Modulation of Tumor-Associated Macrophage Polarity in Immunotherapy of Cancer by Oka, Adwait

“…Despite greater understanding of the molecular mechanisms and the resulting targeted therapeutic strategies, the mortality rate associated with cancer has not…”
Get full text