Natural course of hepatic focal nodular hyperplasia from childhood to adulthood and review of the literature

Natural course of hepatic focal nodular hyperplasia from childhood to adulthood and review of the literature

Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver and constitutes 4% of all primary hepatic tumors in pediatric population. Imaging characteristics of FNH in adults are well known, but those in children have rarely been reported. Here we describe the natural course...

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Bibliographic Details
Published in:The Turkish journal of gastroenterology Vol. 28; no. 6; pp. 492 - 497
Main Authors: Gürses, Cemil, Okşar, Feyzan Seher, Erol, Bekir, Yalçın, Mustafa, Kahvecioğlu, Nevfel, Alparslan, Ahmet Şükrü
Format: Journal Article
Language:English
Published: Turkey AVES 01-11-2017
Subjects:
Adolescent
Adult
CAT scans
Child
Disease Progression
Enzymes
Female
Focal Nodular Hyperplasia - diagnostic imaging
Focal Nodular Hyperplasia - enzymology
Focal Nodular Hyperplasia - pathology
Humans
Hyperplasia
Liver
Liver - diagnostic imaging
Liver - enzymology
Liver - pathology
Liver Function Tests
Male
Tomography, X-Ray Computed
Young Adult
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Summary:Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver and constitutes 4% of all primary hepatic tumors in pediatric population. Imaging characteristics of FNH in adults are well known, but those in children have rarely been reported. Here we describe the natural course of a giant hepatic FNH, which was followed up from childhood to adulthood for 12 years using computed tomography (CT) imaging and liver enzyme tests (LET). Differences in CT imaging characteristics were demonstrated. Changes were found in the FNH size in CT images and they were correlated with LET findings. The regression of FNH in our case was compared with the findings in the literature. Hepatic capsular retraction was observed in a benign focal liver lesion in the medical literature for the first time.
ISSN:1300-4948
2148-5607
DOI:10.5152/tjg.2017.17227