Search Results - "Ojkic, Nikola"

Surface-to-volume scaling and aspect ratio preservation in rod-shaped bacteria by Ojkic, Nikola, Serbanescu, Diana, Banerjee, Shiladitya

“…Rod-shaped bacterial cells can readily adapt their lengths and widths in response to environmental changes. While many recent studies have focused on the…”
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Antibiotic Resistance via Bacterial Cell Shape-Shifting by Ojkic, Nikola, Serbanescu, Diana, Banerjee, Shiladitya

“…Bacteria have evolved to develop multiple strategies for antibiotic resistance by effectively reducing intracellular antibiotic concentrations or antibiotic…”
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Nutrient-Dependent Trade-Offs between Ribosomes and Division Protein Synthesis Control Bacterial Cell Size and Growth by Serbanescu, Diana, Ojkic, Nikola, Banerjee, Shiladitya

“…Cell size control emerges from a regulated balance between the rates of cell growth and division. In bacteria, simple quantitative laws connect cellular growth…”
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Mechanical feedback promotes bacterial adaptation to antibiotics by Banerjee, Shiladitya, Lo, Klevin, Ojkic, Nikola, Stephens, Roisin, Scherer, Norbert F., Dinner, Aaron R.

“…To maximize their fitness, cells must be able to respond effectively to stresses. This demands making trade-offs between processes that conserve resources to…”
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Cell-wall remodeling drives engulfment during Bacillus subtilis sporulation by Ojkic, Nikola, López-Garrido, Javier, Pogliano, Kit, Endres, Robert G

“…When starved, the Gram-positive bacterium forms durable spores for survival. Sporulation initiates with an asymmetric cell division, creating a large mother…”
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Bistable forespore engulfment in Bacillus subtilis by a zipper mechanism in absence of the cell wall by Ojkic, Nikola, López-Garrido, Javier, Pogliano, Kit, Endres, Robert G

“…To survive starvation, the bacterium Bacillus subtilis forms durable spores. The initial step of sporulation is asymmetric cell division, leading to a large…”
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Bacterial cell shape control by nutrient-dependent synthesis of cell division inhibitors by Ojkic, Nikola, Banerjee, Shiladitya

“…By analyzing cell size and shapes of the bacterium Bacillus subtilis under nutrient perturbations, protein depletion, and antibiotic treatments, we find that…”
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Cellular resource allocation strategies for cell size and shape control in bacteria by Serbanescu, Diana, Ojkic, Nikola, Banerjee, Shiladitya

“…Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions via changes in cell morphologies and macromolecular composition…”
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A Roadblock-and-Kill Mechanism of Action Model for the DNA-Targeting Antibiotic Ciprofloxacin by Ojkic, Nikola, Lilja, Elin, Direito, Susana, Dawson, Angela, Allen, Rosalind J, Waclaw, Bartlomiej

“…Fluoroquinolones, antibiotics that cause DNA damage by inhibiting DNA topoisomerases, are clinically important, but their mechanism of action is not yet fully…”
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Phase separation in the outer membrane of Escherichia coli by Benn, Georgina, Mikheyeva, Irina V., Inns, Patrick George, Forster, Joel C., Ojkic, Nikola, Bortolini, Christian, Ryadnov, Maxim G., Kleanthous, Colin, Silhavy, Thomas J., Hoogenboom, Bart W.

“…Gram-negative bacteria are surrounded by a protective outer membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer…”
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Differential growth regulates asymmetric size partitioning in Caulobacter crescentus by Ng, Tin Wai, Ojkic, Nikola, Serbanescu, Diana, Banerjee, Shiladitya

“…Cell size regulation has been extensively studied in symmetrically dividing cells, but the mechanisms underlying the control of size asymmetry in…”
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α-Actinin and fimbrin cooperate with myosin II to organize actomyosin bundles during contractile-ring assembly by Laporte, Damien, Ojkic, Nikola, Vavylonis, Dimitrios, Wu, Jian-Qiu

“…The actomyosin contractile ring assembles through the condensation of a broad band of nodes that forms at the cell equator in fission yeast cytokinesis. The…”
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Kinetics of myosin node aggregation into a contractile ring by Ojkic, Nikola, Vavylonis, Dimitrios

“…We study a stochastic aggregation model for the assembly of the contractile ring from a broad band of nodes during cytokinesis in fission yeast. We found that…”
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Chromosome Translocation Inflates Bacillus Forespores and Impacts Cellular Morphology by Lopez-Garrido, Javier, Ojkic, Nikola, Khanna, Kanika, Wagner, Felix R., Villa, Elizabeth, Endres, Robert G., Pogliano, Kit

“…The means by which the physicochemical properties of different cellular components together determine bacterial cell shape remain poorly understood. Here, we…”
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Reduced adhesion between cells and substrate confers selective advantage in bacterial colonies by Watson, Craig, Hush, Paul, Williams, Joshua, Dawson, Angela, Ojkic, Nikola, Titmuss, Simon, Waclaw, Bartlomiej

“…Microbial colonies cultured on agar Petri dishes have become a model system to study biological evolution in populations expanding in space. Processes such as…”
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Model of the Role of Actin Crosslinker Proteins during Contractile Ring Assembly in Fission Yeast by Ojkic, Nikola, Vavylonis, Dimitrios

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Reduced adhesion between cells and substrate confers selective advantage in bacterial colonies(a)(a) Contribution to the Focus Issue Evolutionary Modeling and Experimental Evolution edited by José Cuesta, Joachim Krug and Susanna Manrubia by Watson, Craig, Hush, Paul, Williams, Joshua, Dawson, Angela, Ojkic, Nikola, Titmuss, Simon, Waclaw, Bartlomiej

“…Microbial colonies cultured on agar Petri dishes have become a model system to study biological evolution in populations expanding in space. Processes such as…”
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Model of myosin node aggregation into a contractile ring: the effect of local alignment by Ojkic, Nikola, Wu, Jian-Qiu, Vavylonis, Dimitrios

“…Actomyosin bundles frequently form through aggregation of membrane-bound myosin clusters. One such example is the formation of the contractile ring in fission…”
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Bistable Forespore Engulfment in Bacillus subtilis by a Zipper Mechanism in Absence of the Cell Wall: e1003912 by Ojkic, Nikola, López-Garrido, Javier, Pogliano, Kit, Endres, Robert G

“…To survive starvation, the bacterium Bacillus subtilis forms durable spores. The initial step of sporulation is asymmetric cell division, leading to a large…”
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Model of Condensation of an Actomyosin Network into a Contractile Ring for Fission Yeast Cell Division: The Effect of Actin Cross-Linkers Alpha-Actinin and Fimbrin by Ojkic, Nikola, Laporte, Damien, Wu, Jian-Qiu, Vavylonis, Dimitrios

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