Search Results - "Ojha, Himanshu"

Estimation of antiradical properties of antioxidants using DPPH assay: A critical review and results by Mishra, Krishnanand, Ojha, Himanshu, Chaudhury, Nabo Kumar

“…► DPPH assay is a common antioxidant assay. ► Variations in antiradical properties using DPPH Assay observed in literature. ► Examples highlighted with case…”
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Biological Evaluation and Binding Mechanism of 5-HT7 Specific Arylpiperazinyl–Alkyl Benzothiazolone: Radiobiology and Photo-physical Studies by Kumari, Neelam, Singh, Deepika, Singh, Priya, Mishra, Akanksha, Gond, Chandraprakash, Ojha, Himanshu, Tiwari, Anjani Kumar

“…Diversely substituted methoxy derivatives of arylpiperazinyl–alkyl benzothiazolone has been evaluated as specific probe for 5HT 7 . To determine the best…”
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Adsorption characteristics of magnetized biochar derived from Citrus limetta peels by Mishra, Ayushi, Ojha, Himanshu, Pandey, Jyoti, Tiwari, Anjani Kumar, Pathak, Mallika

“…Agro-industrial waste is an alarming issue that needs to be addressed. Waste valorization is an effective technique to deal with such effectively. Synthesis of…”
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Binding of ethyl pyruvate to bovine serum albumin: Calorimetric, spectroscopic and molecular docking studies by Pathak, Mallika, Mishra, Rashmi, Agarwala, Paban K., Ojha, Himanshu, Singh, Bhawna, Singh, Anju, Kukreti, Shrikant

“…[Display omitted] •ITC study showed binding of ethyl pyruvate with BSA with high binding affinity.•Ethyl pyruvate binding caused conformation alteration of…”
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Design, synthesis and biological evaluation of antimalarial activity of new derivatives of 2,4,6-s-triazine by Pathak, Mallika, Ojha, Himanshu, Tiwari, Anjani K., Sharma, Deepti, Saini, Manisha, Kakkar, Rita

“…Dihydrofolate reductase (DHFR) is an important enzyme for de novo synthesis of nucleotides in Plasmodium falciparum and it is essential for cell proliferation…”
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Design and in silico screening of aryl allyl mercaptan analogs as potential histone deacetylases (HDAC) inhibitors by Singhal, Sugandha, Pathak, Mallika, Agrawala, Paban K., Ojha, Himanshu

“…The Zn+2 HDACIs show promising anticancer activity. Allyl mercaptan (AM), a metastabilzed monomeric form of diallyl disulphide (DADS) shows better HDACI…”
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Healing efficacy and dermal toxicity of topical silver nanoparticles-loaded hydrogel in Sprague–Dawley rats by Sharma, Deepti, Sharma, Navneet, Bal, Roy, Pathak, Mallika, Kumar, Vinod, Ojha, Himanshu

“…Traumatic wounds are the wounds that damage both the skin and the underlying tissues. Bacterial load in wounded tissue triggers elongation of the inflammation…”
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Interaction of DNA Minor Groove Binder Hoechst 33258 with Bovine Serum Albumin by Ojha, Himanshu, Murari, Bhaskar Mohan, Anand, Sneh, Hassan, Mohd Imtaiyaz, Ahmad, Faizan, Chaudhury, Nabo Kumar

“…Hoechst 33258 belongs to bisbenzimidazole class of molecules having anticancer properties for their ability to inhibit topoisomerase and many other cellular…”
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Medical management of ionizing radiation-induced skin injury by Ojha, Himanshu, Choudhary, Vikram, Sharma, Deepti, Nair, Ashrit, Sharma, Navneet, Pathak, Mallika, Hosakote Shivkumar, Sharma, Rakesh, Kaushik, Vinod, Singhal, Rahul, Goel, Rajeev

“…Skin radiation exposure occurs during planned or unplanned radiation events, such as radiotherapy or nuclear radiation accidents, respectively, resulting into…”
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Multispectroscopic studies of binding interaction of phosmet with bovine hemoglobin by Kaur, Lajpreet, Singh, Anju, Datta, Anupama, Ojha, Himanshu

“…[Display omitted] •The intrinsic fluorescence of BHb is quenched by phosmet via dynamic mechanism.•FTIR and CD study revealed the secondary structural changes…”
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Removal of an organophosphorus pesticide by engineered silylated graphene oxide by Kaur, Lajpreet, Mishra, Ayushi, Sharma, Aanchal, Pathak, Mallika, Ojha, Himanshu

“…The removal of organophosphorus pesticides is the growing concern. The pesticides are biomagnified in food chain, causing greater health hazards to humans and…”
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Synthesis, characterization of 1,2,4-triazole Schiff base derived 3d-metal complexes: Induces cytotoxicity in HepG2, MCF-7 cell line, BSA binding fluorescence and DFT study by Tyagi, Prateek, Tyagi, Monika, Agrawal, Swati, Chandra, Sulekh, Ojha, Himanshu, Pathak, Mallika

“…Two novel Schiff base ligands H2L1 and H2L2 have been synthesized by condensation reaction of amine derivative of 1,2,4-triazole moiety with…”
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Curcumin-loaded liposomes for wound healing: Preparation, optimization, in-vivo skin permeation and bioevaluation by Choudhary, Vikram, Shivakumar, Hosakote, Ojha, Himanshu

“…[Display omitted]…”
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Synthesis and bio-evaluation of newer dihydropyridines and tetrahydropyridines based glycomimetic azasugars by Deswal, Nidhi, Takkar, Priya, Kaur, Lajpreet, Ojha, Himanshu, Kumar, Rakesh

“…[Display omitted] •A flexible strategy for the preparation of azasugars was designed & synthesized.•The synthesized azasugars were evaluated for α-glucosidase…”
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Binding studies of potential amyloid-β inhibiting chalcone derivative with bovine serum albumin by Daksh, Shivani, Gond, Chandraprakash, Kumar, Nikhil, Kaur, Lajpreet, Ojha, Himanshu, Deep, Shashank, Datta, Anupama

“…[Display omitted] •UV–Vis absorption studies reveals the interaction between L1 and BSA.•Intrinsic fluorescence of BSA is quenched by L1 via static quenching…”
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Binding interactions of Vildagliptin with pepsin: A multi-spectroscopic and in-silico approach and a comparative account with metformin by Verma, Piyush, Kaur, Lajpreet, Aswal, Priyanka, Singh, Anju, Pandey, Rashmi, Ojha, Himanshu, Pathak, Mallika

“…[Display omitted] •Vildagliptin binds with pepsin via hydrogen-bonding and Van der Waal interactions.•Thermodynamic parameters suggested exothermic and…”
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Binding studies for the interaction between hazardous organophosphorus compound phosmet and lysozyme: Spectroscopic and In-silico analyses by Kaur, Lajpreet, Rahman, Afreen J., Singh, Anju, Pathak, Mallika, Datta, Anupama, Singhal, Rahul, Ojha, Himanshu

“…[Display omitted] •Fluorescence study confirms non-covalent specific binding of phosmet with lysozyme.•CD and FT-IR studies reveal changes in secondary…”
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Spectroscopic studies of binding interactions of 2-chloroethylphenyl sulphide with bovine serum albumin by Rahman, Afreen Jahan, Kaur, Lajpreet, Pathak, Mallika, Singh, Anju, Verma, Piyush, Singhal, Rahul, Kumar, Vinod, Ojha, Himanshu

“…[Display omitted] •Binding interaction of CEPS with BSA was investigated using various spectroscopic techniques.•The fluorescence quenching of BSA induced by…”
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Spectroscopic and molecular modelling study of binding mechanism of bovine serum albumin with phosmet by Rahman, Afreen Jahan, Sharma, Deepti, Kumar, Deepanshu, Pathak, Mallika, Singh, Anju, Kumar, Vinod, Chawla, Raman, Ojha, Himanshu

“…Phosmet exerts its neurotoxicity by inhibiting acetylcholinesterase that catalyzes the degradation of acetylcholine (a neurotransmitter). Serum proteins are…”
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Design, synthesis, characterization and evaluation of methionine-ABO based TSPO ligand by Srivastava, Pooja, Kaul, Ankur, Yadav, Pankaj, Ojha, Himanshu, Tiwari, Anjani Kumar

“…•Incorporation of methionine methyl ester into ABO structure to enhance TSPO targeting.•Design and validation of halogen-substituted analogs (ABMO-Br and…”
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